sorbitol has been researched along with Alcoholic Cirrhosis in 5 studies
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In patients with various liver diseases, it was correlated more closely to the fractional clearance of indocyanine green (r = 0." | 3.67 | Steady-state extrarenal sorbitol clearance as a measure of hepatic plasma flow. ( Bircher, J; Bosch, J; Chesta, J; Eggers, R; Lange, H; Loesgen, H; Navasa, M; Pohl, S; Zeeh, J, 1988) |
| "Levetiracetam is an antiepileptic drug approved for use as adjunctive therapy in adults with partial-onset seizures." | 2.71 | Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): characterization by dynamic liver function tests. ( Brockmöller, J; Coupez, R; Lochs, H; Roots, I; Thomsen, T; Wittstock, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brockmöller, J | 1 |
| Thomsen, T | 1 |
| Wittstock, M | 1 |
| Coupez, R | 1 |
| Lochs, H | 1 |
| Roots, I | 1 |
| McClain, CJ | 1 |
| Kromhout, JP | 1 |
| Zieve, L | 1 |
| Duane, WC | 1 |
| Lotterer, E | 1 |
| Gressner, AM | 1 |
| Kropf, J | 1 |
| Grobe, E | 1 |
| von Knebel, D | 1 |
| Bircher, J | 2 |
| Molino, G | 1 |
| Avagnina, P | 1 |
| Ballarè, M | 1 |
| Torchio, M | 1 |
| Niro, AG | 1 |
| Aurucci, PE | 1 |
| Grosso, M | 1 |
| Fava, C | 1 |
| Zeeh, J | 1 |
| Lange, H | 1 |
| Bosch, J | 1 |
| Pohl, S | 1 |
| Loesgen, H | 1 |
| Eggers, R | 1 |
| Navasa, M | 1 |
| Chesta, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake[NCT01168687] | 46 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome of this study is to determine the effect of levetiracetam on alcohol consumption as measured by change in # of drinks during each treatment period. (NCT01168687)
Timeframe: During each 14 day treatment period
| Intervention | number of drinks per treatment period (Mean) |
|---|---|
| All Subjects (n = 46) Placebo | 41.2 |
| All Subjects (n = 46) Levetiracetam | 45.4 |
2 trials available for sorbitol and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): characterization by dynamic liver function tests.
Topics: Adult; Anticonvulsants; Caffeine; Humans; Kidney Function Tests; Levetiracetam; Lidocaine; Liver Cir | 2005 |
Effect of sorbitol on psychomotor function: its use in alcoholic cirrhosis.
Topics: Humans; Intestine, Small; Lactulose; Liver Cirrhosis, Alcoholic; Male; Mental Processes; Sorbitol | 1981 |
3 other studies available for sorbitol and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Higher levels of serum aminoterminal type III procollagen peptide, and laminin in alcoholic than in nonalcoholic cirrhosis of equal severity.
Topics: Adult; Aged; Biomarkers; Female; Galactose; Humans; Laminin; Liver Cirrhosis; Liver Cirrhosis, Alcoh | 1992 |
Combined evaluation of total and functional liver plasma flows and intrahepatic shunting.
Topics: Adult; Blood Flow Velocity; Catheterization, Peripheral; Clinical Protocols; Female; Hepatic Veins; | 1991 |
Steady-state extrarenal sorbitol clearance as a measure of hepatic plasma flow.
Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Cholestasis, Extrahepatic; Female; Hepatitis; Humans; | 1988 |