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sorbitol and Albuminuria

sorbitol has been researched along with Albuminuria in 15 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"To assess the therapeutic effect of losartan on type 2 diabetes mellitus (DM2) with gas chromatography (GC)-based metabonomics."7.74[Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics]. ( Gao, P; Lu, X; Shi, XZ; Xu, GW; Yuan, KL, 2007)
"We investigated the role played by sorbitol accumulation in the kidney in the development of diabetic albuminuria."7.72Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency. ( Ii, S; Itakura, M; Kudo, E; Moritani, M; Ohta, M; Tachikawa, T; Yamaoka, T; Yoshimoto, K, 2004)
"Sorbinil treatment completely prevented renal cortical sorbital accumulation, but did not abolish kidney enlargement or the increase in ultrafiltration pressure and glomerular filtration rate."5.28Sorbinil does not prevent hyperfiltration, elevated ultrafiltration pressure and albuminuria in streptozotocin-diabetic rats. ( Aperia, A; Celsi, G; Eklöf, AC; Körner, A; Linné, T; Persson, B, 1992)
"Sodium-glucose co-transporter type 2 inhibitors (luseogliflozin 5 mg/day or canagliflozin 100 mg/day) reduced body weight, HbA1c, albuminuria, estimated glomerular filtration rate and office blood pressure."3.85Sodium-glucose co-transporter type 2 inhibitors reduce evening home blood pressure in type 2 diabetes with nephropathy. ( Kishimoto, M; Ohta, M; Suzuki, H; Takenaka, T; Tomonaga, O, 2017)
" Serum-advanced glycation end-products level, malonaldehyde level, sorbitol concentration of red blood cell, 24 h albuminuria excretion were significantly decreased, whereas activity of serum superoxide dismutase and glutathione peroxidase and creatinine clearance rate were increased by mangiferin."3.76Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats. ( Cui, X; Li, W; Li, X; Sun, X; Zhu, Q, 2010)
"To assess the therapeutic effect of losartan on type 2 diabetes mellitus (DM2) with gas chromatography (GC)-based metabonomics."3.74[Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics]. ( Gao, P; Lu, X; Shi, XZ; Xu, GW; Yuan, KL, 2007)
"We investigated the role played by sorbitol accumulation in the kidney in the development of diabetic albuminuria."3.72Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency. ( Ii, S; Itakura, M; Kudo, E; Moritani, M; Ohta, M; Tachikawa, T; Yamaoka, T; Yoshimoto, K, 2004)
"Epalrestat is an inhibitor of aldose reductase in the polyol pathway and is used for the management of diabetic neuropathy clinically."1.51The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation. ( Aa, JY; Ding, F; Gao, HX; He, J; Sun, RB; Wang, GJ; Wang, JK; Xie, Y; Yang, N; Zeng, CH; Zhang, JW; Zhu, XD, 2019)
"Sorbinil treatment completely prevented renal cortical sorbital accumulation, but did not abolish kidney enlargement or the increase in ultrafiltration pressure and glomerular filtration rate."1.28Sorbinil does not prevent hyperfiltration, elevated ultrafiltration pressure and albuminuria in streptozotocin-diabetic rats. ( Aperia, A; Celsi, G; Eklöf, AC; Körner, A; Linné, T; Persson, B, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's5 (33.33)18.2507
2000's4 (26.67)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takenaka, T1
Kishimoto, M1
Ohta, M2
Tomonaga, O1
Suzuki, H1
He, J1
Gao, HX1
Yang, N1
Zhu, XD1
Sun, RB1
Xie, Y1
Zeng, CH1
Zhang, JW1
Wang, JK1
Ding, F1
Aa, JY1
Wang, GJ1
Yuan, KL1
Shi, XZ1
Lu, X1
Gao, P1
Xu, GW1
Li, X2
Cui, X1
Sun, X1
Zhu, Q1
Li, W1
Ouchi, H1
Isogai, S2
Ii, S1
Kudo, E1
Yamaoka, T1
Tachikawa, T1
Moritani, M1
Itakura, M1
Yoshimoto, K1
Fagius, J1
Jameson, S1
Soulis-Liparota, T1
Cooper, ME1
Dunlop, M1
Jerums, G1
Lever, M1
Sizeland, PC1
Bason, LM1
Hayman, CM1
Robson, RA1
Chambers, ST1
Inokuchi, T1
Ohe, K1
Yoshii, H1
Uchino, H1
Ohmura, C1
Watanabe, K1
Tanaka, Y1
Kawamori, R1
Brownlee, M1
Körner, A1
Celsi, G1
Eklöf, AC1
Linné, T1
Persson, B1
Aperia, A1
Tilton, RG1
Chang, K1
Pugliese, G1
Eades, DM1
Province, MA1
Sherman, WR1
Kilo, C1
Williamson, JR1
Kowluru, A1
Kowluru, R1
Bitensky, MW1
Corwin, EJ1
Solomon, SS1
Johnson, JD1

Reviews

1 review available for sorbitol and Albuminuria

ArticleYear
[Diabetic nephropathy--predictive methods].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10

    Topics: Albuminuria; Animals; Biomarkers; Collagen Type IV; Diabetic Nephropathies; Fibronectins; Fructose;

2002

Trials

2 trials available for sorbitol and Albuminuria

ArticleYear
Effects of aldose reductase inhibitor treatment in diabetic polyneuropathy - a clinical and neurophysiological study.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:11

    Topics: Adult; Albuminuria; Aldehyde Reductase; Autonomic Nervous System; Clinical Trials as Topic; Diabetic

1981
Abnormal glycine betaine content of the blood and urine of diabetic and renal patients.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Oct-14, Volume: 230, Issue:1

    Topics: Adult; Albuminuria; Betaine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Fe

1994

Other Studies

12 other studies available for sorbitol and Albuminuria

ArticleYear
Sodium-glucose co-transporter type 2 inhibitors reduce evening home blood pressure in type 2 diabetes with nephropathy.
    Diabetes & vascular disease research, 2017, Volume: 14, Issue:3

    Topics: Albuminuria; Biomarkers; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Canag

2017
The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation.
    Acta pharmacologica Sinica, 2019, Volume: 40, Issue:1

    Topics: Albuminuria; Aldehyde Reductase; Animals; Diabetic Nephropathies; Enzyme Inhibitors; Fructose; Inosi

2019
[Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2007, Volume: 29, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Biomarkers; Chromatography, Gas; Creatinine; Deoxyguanosin

2007
Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:6

    Topics: Albuminuria; Animals; Blood Glucose; Cell Proliferation; Cells, Cultured; Collagen Type IV; Creatini

2010
Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency.
    Diabetologia, 2004, Volume: 47, Issue:3

    Topics: Albuminuria; Aldehyde Reductase; Animals; Diabetic Nephropathies; Humans; L-Iditol 2-Dehydrogenase;

2004
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat.
    Diabetologia, 1995, Volume: 38, Issue:4

    Topics: Albuminuria; Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Body Weight; Butylated Hydrox

1995
Effect of an aldose reductase inhibitor on glomerular basement membrane anionic sites in streptozotocin-induced diabetic rats.
    Diabetes research and clinical practice, 1995, Volume: 30, Issue:2

    Topics: Administration, Oral; Albuminuria; Aldehyde Reductase; Animals; Anions; Basement Membrane; Blood Glu

1995
Clinical usefulness of measuring urinary polyol excretion by gas-chromatography/mass-spectrometry in type 2 diabetes to assess polyol pathway activity.
    Diabetes research and clinical practice, 2001, Volume: 51, Issue:2

    Topics: Adult; Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retino

2001
Glycosylation of proteins and microangiopathy.
    Hospital practice (Office ed.), 1992, Volume: 27 Suppl 1

    Topics: Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diglycerides; Dogs; Gl

1992
Sorbinil does not prevent hyperfiltration, elevated ultrafiltration pressure and albuminuria in streptozotocin-diabetic rats.
    Diabetologia, 1992, Volume: 35, Issue:5

    Topics: Albuminuria; Aldehyde Reductase; Analysis of Variance; Animals; Diabetes Mellitus, Experimental; Glo

1992
Prevention of hemodynamic and vascular albumin filtration changes in diabetic rats by aldose reductase inhibitors.
    Diabetes, 1989, Volume: 38, Issue:10

    Topics: Albuminuria; Aldehyde Reductase; Animals; Cardiac Output; Diabetes Mellitus, Experimental; Fluorenes

1989
Suggested mechanism for the selective excretion of glucosylated albumin. The effects of diabetes mellitus and aging on this process and the origins of diabetic microalbuminuria.
    The Journal of experimental medicine, 1987, Nov-01, Volume: 166, Issue:5

    Topics: Adolescent; Adult; Aging; Albuminuria; Animals; Cations; Child; Diabetes Mellitus, Experimental; Dia

1987