Page last updated: 2024-11-06

sorbitol and Ache

sorbitol has been researched along with Ache in 18 studies

D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).

Research Excerpts

ExcerptRelevanceReference
"This study examined the effects of hyperglycemia and treatment with the aldose reductase inhibitor, Tolrestat, on the pain behavior evoked by injection of formalin into the dorsum of a single hind paw."7.69Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats. ( Calcutt, NA; Malmberg, AB; Yaksh, TL; Yamamoto, T, 1994)
"Pain on injection is the most commonly reported adverse event after propofol injection."5.08Pharmacokinetics and pharmacodynamics of propofol in a new solvent. ( Babl, J; Doenicke, AW; Klotz, U; Kugler, J; O'Connor, M; Rau, J; Roizen, MF, 1997)
"This study examined the effects of hyperglycemia and treatment with the aldose reductase inhibitor, Tolrestat, on the pain behavior evoked by injection of formalin into the dorsum of a single hind paw."3.69Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats. ( Calcutt, NA; Malmberg, AB; Yaksh, TL; Yamamoto, T, 1994)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199012 (66.67)18.7374
1990's4 (22.22)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Cucurnia, I1
Pudda, A1
Madonna, V1
Berruto, M1
Zaffagnini, S1
Liu, QS1
Pang, ZR1
Liu, R1
He, GR1
Cui, J1
Yin, XY1
Hyams, JS1
Calcutt, NA1
Malmberg, AB1
Yamamoto, T1
Yaksh, TL1
Doenicke, AW1
Roizen, MF1
Rau, J1
O'Connor, M1
Kugler, J1
Klotz, U1
Babl, J1
Albrechtsson, U1
Wiesenfeld-Hallin, Z1
Xu, XJ1
Hughes, J1
Horwell, DC1
Hökfelt, T1
Doenicke, A1
Kugler, A1
Vollmann, N1
Pitts, NE1
Vreeland, F1
Shaw, GL1
Peterson, MJ1
Mehta, DJ1
Collier, J1
Gundersen, K1
Sovak, M1
Halkovich, CA1
Foster, SJ1
Jain, NK1
Rosenberg, DB1
Ulahannan, MJ1
Glasser, MJ1
Pitchumoni, CS1
De Marzi, S1
Morini, V1
Stillman, AE1
Haase, J1
Jepsen, BV1
Bech, H1
Langeback, E1
Nepomuceno, CS1
Miller, JM1
Ortner, WD1
Kubin, H1
Kollar, WA1
Occleshaw, JV1
Holyland, JN1
Jaisle, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Observational Study to Evaluate the Prevalence of Rotator Cuff Tears in Hemiplegic Shoulders[NCT00998868]51 participants (Actual)Observational2008-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Muscle Strength, Measured by Physical Examination, Per Medical Research Council Muscle Strength Grading System

"Muscle strength was measured for forward flexion and abduction of the shoulder per Medical Research Council (MRC) scale in each participants. Their mean +/- SD were calculated in each group.~MRC scale:~Grade 5: Normal and can move against full resistance. Grade 4: Reduced but can move against resistance. Grade 3: Can move only against gravity Grade 2: Can move without gravity Grade 1: Only a trace of movement Grade 0: No movement." (NCT00998868)
Timeframe: within one month after enrollment

InterventionUnits on a scale (minimum 0, maximum 5) (Mean)
Hemiplegia1.96

Rotator Cuff Tear of the Hemiplegic Shoulder, Confirmed by Ultrasonography

All patients underwent ultrasonography (USG) for the both, affected and unaffected, shoulders. USG routinely examined biceps, subscapularis, supraspinatus, and infraspinatus tendons as for the partial or complete tears, calcifications, bony irregularity and bursal swellings. (NCT00998868)
Timeframe: within one month after enrollment

Interventionparticipants (Number)
Hemiplegia29

Rotator Cuff Tear of the Unaffected Shoulder, Confirmed by Ultrasonography

All patients were performed ultrasonography (USG) for the both, affected and unaffected, shoulders. USG routinely examined biceps, subscapularis, supraspinatus, and infraspinatus tendons as for the partial or complete tears, calcifications, bony irregularity and bursal swellings. (NCT00998868)
Timeframe: within one month after enrollment

Interventionparticipants (Number)
Hemiplegia18

Subluxation of the Glenohumeral Joint, Confirmed by Physical Examination

The glenohumeral joint subluxation was examined by palpating the subacromial regions of the both sides and comparing the affected side with the unaffected side while patients are seated and relaxed. If the palpated space between the acromion and the humeral head was wider on the affected side by one half finger breath or more, it was judged to be subluxation. (NCT00998868)
Timeframe: within one month after enrollment

Interventionparticipants (Number)
Hemiplegia21

Trials

3 trials available for sorbitol and Ache

ArticleYear
Pharmacokinetics and pharmacodynamics of propofol in a new solvent.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Combinations; E

1997
Clinical experience with sorbinil--an aldose reductase inhibitor.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:4 Suppl 1

    Topics: Aldehyde Reductase; Animals; Autonomic Nervous System Diseases; Blood Glucose; Clinical Trials as To

1986
Comparative study of the effects of Conray 280 and Dimer X in lumbar radiculography.
    The British journal of radiology, 1971, Volume: 44, Issue:528

    Topics: Acetamides; Adult; Contrast Media; Headache; Humans; Hypotension; Intervertebral Disc Displacement;

1971

Other Studies

15 other studies available for sorbitol and Ache

ArticleYear
Patient-reported outcomes of intra-articular hyaluronic acid for osteoarthritis of the knee: a prospective and multicentric case series.
    Musculoskeletal surgery, 2022, Volume: 106, Issue:3

    Topics: Humans; Hyaluronic Acid; Injections, Intra-Articular; Osteoarthritis, Knee; Pain; Pain Measurement;

2022
Effective compounds group of Mongolian prescriptions BAIMAI-SAN protect against peripheral neuropathy in lower limbs of rats through neuro protective effect.
    Journal of ethnopharmacology, 2011, Jun-01, Volume: 135, Issue:3

    Topics: Animals; Brain; Cell Culture Techniques; Cell Survival; Cells, Cultured; Diabetes Complications; Dia

2011
Chronic abdominal pain caused by sorbitol malabsorption.
    The Journal of pediatrics, 1982, Volume: 100, Issue:5

    Topics: Abdomen; Child, Preschool; Chronic Disease; Female; Humans; Malabsorption Syndromes; Pain; Sorbitol

1982
Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats.
    Pain, 1994, Volume: 58, Issue:3

    Topics: Aldehyde Reductase; Animals; Behavior, Animal; Body Weight; Diabetes Mellitus, Experimental; Female;

1994
Side-effects at phlebography with ionized and non-ionized contrast medium.
    Diagnostic imaging, 1979, Volume: 48, Issue:4

    Topics: Humans; Iodobenzoates; Leg; Meglumine; Metrizamide; Metrizoic Acid; Pain; Phlebography; Sorbitol; Th

1979
PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:18

    Topics: Analgesics; Animals; Cholecystokinin; Drug Synergism; Female; Galanin; Indoles; Injections, Spinal;

1990
Venous tolerance to etomidate in lipid emulsion or propylene glycol (hypnomidate)
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:7

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Drug Combinations; Emulsions; Ethylene Glycols; Et

1990
Current contrast media and ioxilan. Comparative evaluation of vascular pain by aversion conditioning.
    Investigative radiology, 1988, Volume: 23 Suppl 1

    Topics: Animals; Conditioning, Psychological; Contrast Media; Female; Iohexol; Iopamidol; Osmolar Concentrat

1988
Sorbitol intolerance in adults.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:9

    Topics: Abdomen; Adult; Black People; Breath Tests; Colonic Diseases, Functional; Diagnosis, Differential; D

1985
[Use of meglumine indomethacin in the treatment of pain due to neoplastic diseases].
    La Clinica terapeutica, 1972, Jul-19, Volume: 62, Issue:2

    Topics: Adult; Aged; Amino Sugars; Analgesics; Female; Humans; Indomethacin; Male; Middle Aged; Neoplasm Met

1972
Hepatotoxic reaction to iodipamide meglumine injection.
    JAMA, 1974, Jun-10, Volume: 228, Issue:11

    Topics: Acute Disease; Aged; Amino Sugars; Aspartate Aminotransferases; Chemical and Drug Induced Liver Inju

1974
Spinal fracture following radiculography using meglumine iothalamate (Conray).
    Neuroradiology, 1973, Volume: 6, Issue:2

    Topics: Adipates; Adult; Contrast Media; Diazepam; Female; Fractures, Bone; Humans; Hypesthesia; Iothalamic

1973
Shoulder arthrography in hemiplegic patients.
    Archives of physical medicine and rehabilitation, 1974, Volume: 55, Issue:2

    Topics: Adult; Aged; Amino Sugars; Contrast Media; Diatrizoate; Female; Hemiplegia; Humans; Injections, Intr

1974
[Lumbar function myelography with water soluble contrast media in diskopathies].
    Der Radiologe, 1972, Volume: 12, Issue:2

    Topics: Adipates; Adult; Arachnoiditis; Contrast Media; Headache; Humans; Hypotension; Intervertebral Disc D

1972
[Effects and side-effects of lipid and phospatide infusions at the end of gravidity].
    Archiv fur Gynakologie, 1967, Volume: 204, Issue:2

    Topics: Adult; Animals; Cottonseed Oil; Emulsions; Female; Gestational Age; Humans; Infusions, Parenteral; L

1967