Compounds > sorafenib
Page last updated: 2024-09-05

sorafenib and Thyroid Cancer, Anaplastic

sorafenib has been researched along with Thyroid Cancer, Anaplastic in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (53.85)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Bartsch, DK; Di Fazio, P; Holzer, K; Keber, C; Knauff, F; Manoharan, J; Maurer, E; Roth, S; Wächter, S1
Dongmei, H; Jingtai, Z; Linfei, H; Ning, K; Tianze, Z; Wei, W; Weiwei, Y; Xiangqian, Z; Xiangrui, M; Xianhui, R; Xin, W; Xinwei, Y; Yuyang, Q1
Berglund, H; Hariri, M; Malmberg, C; Mortensen, ACL; Papalanis, E; Spiegelberg, D1
Asano, Y; Ishihara, S; Kashiwagi, S; Morisaki, T; Noda, S; Ohira, M; Onoda, N; Takashima, T; Tauchi, Y1
Chang, H; Chang, HS; Kim, SM; Kim, SY; Lee, YS; Park, CS1
Chang, HJ; Chang, HS; Kim, HJ; Kim, J; Kim, SY; Park, CS; Park, KC; Yun, HJ1
Chou, TC; Huang, YT; J Wong, R; Lin, SF; Lu, YL; Wu, MH1
Ito, KI; Ito, Y; Kabu, K; Onoda, N; Sugitani, I; Takahashi, S; Tsukada, K; Yamaguchi, I1
Arai, S; Fukuda, K; Hirata, E; Matsui, J; Nishiyama, A; Ohtsubo, K; Onoda, N; Taira, S; Takeuchi, S; Taniguchi, H; Tanimoto, A; Wang, R; Yamada, T; Yamashita, K; Yano, S1
Bartsch, DK; Doll, D; Greene, BH; Hoffmann, S; Khoruzhyk, M; Ramaswamy, A; Roth, S; Wunderlich, A1
Abdulghani, J; Cooper, T; Derr, J; Dicker, D; El-Deiry, WS; Finnberg, NK; Gallant, JN; Gokare, P; Goldenberg, D; Liao, J; Liu, J; Whitcomb, T1
Chapman, R; Dowlati, A; Fu, P; Lavertu, P; Nagaiah, G; Remick, SC; Savvides, P; Wasman, J; Wright, JJ1
Cohen, MS; Cohen, SM; Mukerji, R; Samadi, AK; Timmermann, BN1

Trials

2 trial(s) available for sorafenib and Thyroid Cancer, Anaplastic

ArticleYear
Sorafenib in Japanese Patients with Locally Advanced or Metastatic Medullary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma.
    Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:9

    Topics: Adult; Alopecia; Antineoplastic Agents; Carcinoma, Neuroendocrine; Diarrhea; Drug Resistance, Neoplasm; Female; Hand-Foot Syndrome; Humans; Hypertension; Japan; Male; Neoplasm Grading; Niacinamide; Patient Dropouts; Phenylurea Compounds; Protein Kinase Inhibitors; Sorafenib; Survival Analysis; Thyroid Carcinoma, Anaplastic; Thyroid Gland; Thyroid Neoplasms; Tumor Burden

2017
Phase II trial of sorafenib in patients with advanced anaplastic carcinoma of the thyroid.
    Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Drug Eruptions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Sorafenib; Survival Analysis; Thyroid Carcinoma, Anaplastic; Thyroid Gland; Thyroid Neoplasms

2013

Other Studies

11 other study(ies) available for sorafenib and Thyroid Cancer, Anaplastic

ArticleYear
Synergic Induction of Autophagic Cell Death in Anaplastic Thyroid Carcinoma.
    Cancer investigation, 2023, Volume: 41, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Autophagy; Cell Death; Cell Line, Tumor; Humans; Male; Panobinostat; Sorafenib; Spheroids, Cellular; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2023
Targeting Aurora-A inhibits tumor progression and sensitizes thyroid carcinoma to Sorafenib by decreasing PFKFB3-mediated glycolysis.
    Cell death & disease, 2023, 03-29, Volume: 14, Issue:3

    Topics: Adenosine Triphosphate; Aurora Kinase A; Cell Line, Tumor; Humans; Phosphofructokinase-2; Protein Kinase Inhibitors; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Xenograft Model Antitumor Assays

2023
Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer.
    Scientific reports, 2023, 10-06, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Mice; Phenylurea Compounds; Protein Kinase Inhibitors; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Tyrosine Kinase Inhibitors

2023
Sorafenib inhibits vascular endothelial cell proliferation stimulated by anaplastic thyroid cancer cells regardless of BRAF mutation status.
    International journal of oncology, 2019, Volume: 55, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Humans; Mutation; Phosphorylation; Proto-Oncogene Proteins B-raf; Signal Transduction; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2019
Synergistic anticancer activity of sorafenib, paclitaxel, and radiation therapy on anaplastic thyroid cancer in vitro and in vivo.
    Head & neck, 2020, Volume: 42, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Paclitaxel; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2020
Synergistic Anticancer Activity of
    International journal of molecular sciences, 2021, Jan-07, Volume: 22, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Drug Synergism; Female; Heterografts; Humans; Hydroxamic Acids; Male; Mice; Middle Aged; Naphthalenes; Radiotherapy; Sorafenib; Thyroid Carcinoma, Anaplastic

2021
Efficacy of adavosertib therapy against anaplastic thyroid cancer.
    Endocrine-related cancer, 2021, 04-29, Volume: 28, Issue:5

    Topics: Animals; Cell Line, Tumor; Humans; Mice; Pyrazoles; Pyrimidinones; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2021
Distribution and Activity of Lenvatinib in Brain Tumor Models of Human Anaplastic Thyroid Cancer Cells in Severe Combined Immune Deficient Mice.
    Molecular cancer therapeutics, 2019, Volume: 18, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Heterografts; Humans; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Phenylurea Compounds; Protein Kinase Inhibitors; Quinolines; Sorafenib; Thyroid Carcinoma, Anaplastic

2019
Pretherapeutic drug evaluation by tumor xenografting in anaplastic thyroid cancer.
    The Journal of surgical research, 2013, Volume: 185, Issue:2

    Topics: Animals; Apoptosis; Benzazepines; Cell Proliferation; Drug Evaluation, Preclinical; Humans; Male; Mice; Mice, Nude; Middle Aged; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Quinazolines; Random Allocation; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Treatment Outcome; Xenograft Model Antitumor Assays

2013
Sorafenib and Quinacrine Target Anti-Apoptotic Protein MCL1: A Poor Prognostic Marker in Anaplastic Thyroid Cancer (ATC).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; Humans; Mice; Mice, Inbred C57BL; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Niacinamide; Phenylurea Compounds; Prognosis; Protein Kinase Inhibitors; Quinacrine; Sorafenib; Thyroid Carcinoma, Anaplastic; Thyroid Gland; Thyroid Neoplasms; Transcription Factor RelA

2016
A novel combination of withaferin A and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers.
    American journal of surgery, 2012, Volume: 204, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Carcinoma; Carcinoma, Papillary; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Humans; Inhibitory Concentration 50; Niacinamide; Phenylurea Compounds; Pyridines; Sorafenib; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Withanolides

2012