Page last updated: 2024-09-05

sorafenib and Neuroblastoma

sorafenib has been researched along with Neuroblastoma in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
He, YQ; Li, DJ; Ni, CX; Qiu, YS; Shen, FM; Zhou, CC1
Fujisaki, H; Hara, J; Nakano, Y; Nitani, C; Okada, K; Yamasaki, K1
Banik, NL; Karmakar, S; Ray, SK; Roy Choudhury, S1
Brown, RE; Chai, H; Luo, AZ; Weerasinghe, P1
Chlenski, A; Cohn, SL; Guerrero, LJ; Kakodkar, NC; Maitland, ML; Peddinti, RR; Salwen, HR; Tian, Y; Yang, Q1
Bull, VH; Rajalingam, K; Thiede, B1
Ara, T; Buettner, R; DeClerck, YA; Jove, R; Jove, V; Nam, S; Seeger, R; Wang, Y; Wu, J; Xin, H; Xu, Y; Yang, F; Yu, H1

Other Studies

7 other study(ies) available for sorafenib and Neuroblastoma

ArticleYear
Zinc supplementation ameliorates sorafenib-induced cognitive impairment through ROS/JNK signaling pathway.
    Biological trace element research, 2023, Volume: 201, Issue:1

    Topics: Animals; Anisomycin; Apoptosis; Cell Line, Tumor; Cognitive Dysfunction; Dietary Supplements; Humans; MAP Kinase Signaling System; Mice; Neuroblastoma; Oxidative Stress; Reactive Oxygen Species; Sorafenib; Zinc

2023
Sorafenib treatment in children with relapsed and refractory neuroblastoma: an experience of four cases.
    Cancer medicine, 2016, Volume: 5, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Male; Neuroblastoma; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Recurrence; Retreatment; Sorafenib; Treatment Outcome

2016
Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplifi
    Investigational new drugs, 2010, Volume: 28, Issue:6

    Topics: Angiogenesis Inducing Agents; Apoptosis; bcl-2-Associated X Protein; Benzenesulfonates; Caspase 3; Cell Cycle; Cell Proliferation; Cell Shape; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Drug Synergism; Flow Cytometry; Gene Amplification; Genistein; Humans; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neuroblastoma; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Pyridines; Signal Transduction; Sorafenib; Telomerase; Treatment Outcome; Tumor Suppressor Protein p53; Up-Regulation

2010
Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line.
    International journal of clinical and experimental pathology, 2010, Apr-23, Volume: 3, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Cell Line, Tumor; Cell Survival; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Humans; In Situ Nick-End Labeling; Neuroblastoma; Niacinamide; Oncogene Protein v-akt; Phenylurea Compounds; Phosphorylation; Pyridines; Signal Transduction; Sorafenib; STAT3 Transcription Factor

2010
Sorafenib inhibits neuroblastoma cell proliferation and signaling, blocks angiogenesis, and impairs tumor growth.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzenesulfonates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; MAP Kinase Signaling System; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Neuroblastoma; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Sorafenib

2012
Sorafenib-induced mitochondrial complex I inactivation and cell death in human neuroblastoma cells.
    Journal of proteome research, 2012, Mar-02, Volume: 11, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzenesulfonates; Cell Line, Tumor; Cell Shape; Cytochromes c; Down-Regulation; Enzyme Activation; Humans; Membrane Potential, Mitochondrial; Mitochondria; NADH Dehydrogenase; Neuroblastoma; Niacinamide; Phenylurea Compounds; Protein Interaction Maps; Proteolysis; Proteome; Pyridines; Reactive Oxygen Species; Signal Transduction; Sorafenib; Superoxide Dismutase

2012
Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.
    Cancer biology & therapy, 2012, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Janus Kinase 2; Lysophospholipids; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinases; Neuroblastoma; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyridines; Signal Transduction; Sorafenib; Sphingosine; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2012