Page last updated: 2024-09-05

sorafenib and Hypertension, Portal

sorafenib has been researched along with Hypertension, Portal in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, Y; Li, A; Luo, R; Zhu, Y1
Bosch, J; Fernandez, M; Garcia-Pras, E; Mejias, M; Miquel, R; Tiani, C1
Bruix, J; Shah, VH1
Heller, J; Hennenberg, M; Kohistani, AZ; Sauerbruch, T; Stark, C; Trebicka, J1
Angermayr, B; Gangl, A; Mitterhauser, M; Peck-Radosavljevic, M; Reiberger, T; Rohr-Udilova, N; Schwabl, P1
Fischer, HP; Granzow, M; Heller, J; Hennenberg, M; Klein, S; Kohistani, Z; Körner, C; Krämer, B; Nischalke, HD; Sauerbruch, T; Stark, C; Trebicka, J1
Blanchet, B; Chaussade, S; Coriat, R; Goldwasser, F; Gouya, H; Legmann, P; Mir, O; Pol, S; Ropert, S; Sogni, P; Vignaux, O1
Ferlitsch, A; Peck-Radosavljevic, M; Pinter, M; Reiberger, T; Rohr-Udilova, N; Sieghart, W1
Abraldes, JG; Bosch, J; D'Amico, M; Fernández, M; García-Pagán, JC; García-Pras, E; Mejías, M1
Chang, CC; Chen, YC; Hsin, IF; Hsu, SJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Lin, YL1

Reviews

1 review(s) available for sorafenib and Hypertension, Portal

ArticleYear
[Therapeutic effect of sorafenib on portal hypertension: research progress and mechanisms].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:1

    Topics: Animals; Humans; Hypertension, Portal; Niacinamide; Phenylurea Compounds; Sorafenib

2014

Trials

1 trial(s) available for sorafenib and Hypertension, Portal

ArticleYear
Reversible decrease of portal venous flow in cirrhotic patients: a positive side effect of sorafenib.
    PloS one, 2011, Feb-14, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Disease Progression; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Liver Neoplasms; Magnetic Resonance Angiography; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Portal Vein; Protein Kinase Inhibitors; Pyridines; Regional Blood Flow; Sorafenib; Survival Analysis

2011

Other Studies

8 other study(ies) available for sorafenib and Hypertension, Portal

ArticleYear
Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:4

    Topics: Animals; Benzenesulfonates; Collateral Circulation; Enteritis; Heme Oxygenase-1; Hepatitis; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Neovascularization, Physiologic; Niacinamide; Nitric Oxide Synthase Type III; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Sorafenib; Splanchnic Circulation

2009
Antiangiogenic therapy: not just for cancer anymore?
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzenesulfonates; Humans; Hypertension, Portal; Liver Cirrhosis; Niacinamide; Phenylurea Compounds; Pyridines; Sorafenib

2009
Sorafenib targets dysregulated Rho kinase expression and portal hypertension in rats with secondary biliary cirrhosis.
    British journal of pharmacology, 2009, Volume: 157, Issue:2

    Topics: Animals; Aorta; Benzenesulfonates; Blotting, Western; Hypertension, Portal; Liver; Liver Cirrhosis, Biliary; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Sorafenib

2009
Sorafenib attenuates the portal hypertensive syndrome in partial portal vein ligated rats.
    Journal of hepatology, 2009, Volume: 51, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Benzenesulfonates; Cell Proliferation; Cytokines; Down-Regulation; Hemodynamics; Hypertension, Portal; Ligation; Male; Neovascularization, Pathologic; Niacinamide; Nitric Oxide Synthase Type III; Phenylurea Compounds; Portal Vein; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sorafenib; Splanchnic Circulation

2009
Hepatic and HSC-specific sorafenib effects in rats with established secondary biliary cirrhosis.
    Laboratory investigation; a journal of technical methods and pathology, 2011, Volume: 91, Issue:2

    Topics: Actins; Animals; Apoptosis; Benzenesulfonates; Caspase 3; Colorimetry; DNA Fragmentation; Hepatic Stellate Cells; Histological Techniques; Hypertension, Portal; Immunohistochemistry; Liver; Liver Cirrhosis, Biliary; Niacinamide; Phenylurea Compounds; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Pyridines; Rats; Sorafenib; Vascular Resistance

2011
The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma--a pilot study.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:1

    Topics: Aged; Benzenesulfonates; Carcinoma, Hepatocellular; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Pilot Projects; Portal Pressure; Protein Kinase Inhibitors; Pyridines; Real-Time Polymerase Chain Reaction; Sorafenib; Syndrome; Treatment Outcome

2012
Effects of the combined administration of propranolol plus sorafenib on portal hypertension in cirrhotic rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, May-15, Volume: 302, Issue:10

    Topics: Animals; Antihypertensive Agents; Benzenesulfonates; Drug Therapy, Combination; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Niacinamide; Phenylurea Compounds; Propranolol; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Sorafenib

2012
The influence of sorafenib on hepatic encephalopathy and the mechanistic survey in cirrhotic rats.
    European journal of clinical investigation, 2012, Volume: 42, Issue:12

    Topics: Animals; Disease Models, Animal; Hepatic Encephalopathy; Humans; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Niacinamide; Oxidative Stress; Phenylurea Compounds; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sorafenib

2012