Page last updated: 2024-09-05

sorafenib and Fibrosis

sorafenib has been researched along with Fibrosis in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's5 (50.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Deng, X; Guo, X; Huang, X; Li, X; Lin, J; Lu, Y; Tan, W; Wang, C; Xie, Y1
Chao, CH; Chen, LH; Chen, Y; Chen, YT; Cheng, HT; Huang, HC; Huang, KH; Huang, KW; Jin, PR; Juang, IP; Lee, TY; Liao, YH; Lin, SL; Lin, TC; Liu, ZY; Sheng, YH; Su, CT; Sung, YC; Wang, HC; Wang, J1
Bi, J; Cao, Y; Li, J; Li, Y; Liang, Q; Liu, J; Liu, Y; Yang, J; Zhou, L1
Barbisan, LF; Cogliati, B; Da Silva, TC; de Albuquerque Landi, MF; Morais, JÁ; Oliveira, CP; Romualdo, GR; Vinken, M1
D'Angelo, S; De Cristofano, R; Secondulfo, M; Sorrentino, P1
Noguchi, S; Takizawa, H; Yamauchi, Y1
Chen, SW; Chiou, JF; Kuo, CC; Kuo, YC; Liang, JA; Lin, LC1
Chen, Z; Duan, Z; Fu, R; Ge, H; Gui, B; Han, J; Jia, L; Ma, X; Ou, Y; Tian, L; Wang, L1
He, C; Li, Q; Liu, C; Liu, Q; Ma, W; Tao, L; Wang, X; Xue, D; Zhang, J; Zhang, W1
Daniele, B; Di Maio, M; Perrone, F1

Reviews

1 review(s) available for sorafenib and Fibrosis

ArticleYear
Novel therapeutic strategies for fibrotic lung disease: a review with a focus on epithelial-mesenchymal transition.
    Recent patents on inflammation & allergy drug discovery, 2014, Volume: 8, Issue:1

    Topics: Airway Remodeling; Animals; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Inflammation Mediators; Lung; Lung Diseases; Myofibroblasts; Niacinamide; Patents as Topic; Phenylurea Compounds; Protein Kinase Inhibitors; Respiratory Mucosa; Sorafenib; Stromal Cells; Transforming Growth Factor beta

2014

Trials

1 trial(s) available for sorafenib and Fibrosis

ArticleYear
Phase 2 study of combined sorafenib and radiation therapy in patients with advanced hepatocellular carcinoma.
    International journal of radiation oncology, biology, physics, 2014, Apr-01, Volume: 88, Issue:5

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemoradiotherapy; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Female; Fibrosis; Hand-Foot Syndrome; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Portal Vein; Radiation Dosage; Sorafenib; Time Factors; Treatment Outcome; Venous Thrombosis

2014

Other Studies

8 other study(ies) available for sorafenib and Fibrosis

ArticleYear
Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis.
    Neoplasia (New York, N.Y.), 2022, Volume: 28

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Fibroblast Growth Factor 1; Fibrosis; Humans; Liver Neoplasms; Mice; Myeloid-Derived Suppressor Cells; Sorafenib; Up-Regulation

2022
Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 346

    Topics: Animals; Collagen; Disease Models, Animal; Drug Carriers; Fibrosis; Kidney; Kidney Diseases; Ligands; Mice; Mice, Inbred C57BL; Myofibroblasts; Nanoparticles; Sorafenib; Ureteral Obstruction

2022
Collagenase-I decorated co-delivery micelles potentiate extracellular matrix degradation and hepatic stellate cell targeting for liver fibrosis therapy.
    Acta biomaterialia, 2022, 10-15, Volume: 152

    Topics: Collagen; Collagenases; Cytokines; Extracellular Matrix; Fibrosis; Glycyrrhetinic Acid; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Micelles; Prodrugs; Prospective Studies; Sorafenib

2022
Sorafenib reduces steatosis-induced fibrogenesis in a human 3D co-culture model of non-alcoholic fatty liver disease.
    Environmental toxicology, 2021, Volume: 36, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Survival; Coculture Techniques; Fibrosis; Hepatic Stellate Cells; Hepatocytes; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Sorafenib; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1

2021
Selection and management of hepatocellular carcinoma patients with sorafenib: recommendations and opinions from an Italian liver unit.
    Future oncology (London, England), 2013, Volume: 9, Issue:4

    Topics: Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Diarrhea; Dose-Response Relationship, Drug; Fibrosis; Hepatitis B; Hepatitis C; Humans; Hypertension; Italy; Liver Cirrhosis; Liver Neoplasms; Middle Aged; Niacinamide; Patient Selection; Phenylurea Compounds; Sorafenib; Weight Loss

2013
Sorafenib ameliorates renal fibrosis through inhibition of TGF-β-induced epithelial-mesenchymal transition.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Actins; Animals; Apoptosis; Cadherins; Cell Line; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Immunohistochemistry; Kidney Diseases; Male; Niacinamide; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Rats; Smad3 Protein; Sorafenib; Transforming Growth Factor beta; Ureteral Obstruction

2015
Sorafenib Inhibits Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Inhibition of Macrophage Infiltration.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:5

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents; Cell Adhesion; Cell Movement; Chemokine CCL2; Chemokine CXCL11; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Humans; Kidney Tubules; Macrophages; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; Niacinamide; Phenylurea Compounds; Receptors, CXCR3; RNA, Messenger; Signal Transduction; Sorafenib; Transforming Growth Factor beta1; Ureter; Ureteral Obstruction

2016
Targeted therapies: Role of sorafenib in HCC patients with compromised liver function.
    Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:9

    Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Clinical Trials, Phase III as Topic; Fibrosis; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Practice Guidelines as Topic; Pyridines; Randomized Controlled Trials as Topic; Sorafenib; Survival Analysis; Time Factors

2009