Page last updated: 2024-09-05

sorafenib and Experimental Neoplasms

sorafenib has been researched along with Experimental Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's14 (77.78)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Jiao, Y; Lu, X; Tang, W; Wu, J; Xin, BT; Zhang, Y; Zheng, Y; Zhou, X1
Chen, Y; Gu, Y; Han, W; Lu, T; Qian, W; Tang, W; Yang, W; Zhang, F; Zhou, X1
Chao, YS; Chen, CH; Chen, CP; Chen, CT; Chou, LH; Hsu, JT; Hsu, T; Huang, CL; Huang, YL; Jiaang, WT; Kuo, PC; Lin, WH; Liu, HE; Lu, CT; Song, JS; Yeh, TK; Yen, KJ; Yen, SC1
Cao, YX; He, YY; Mao, S; Xiao, X; Xie, XX; Xin, MH; Xuan, W; Zhang, S; Zhang, SQ; Zuo, SJ1
Di, D; Han, Y; Li, R; Li, W; Liu, J; Xin, A; Yan, Q; Zhang, Y1
Chen, K; Huang, SZ; Jiang, XJ; Li, LL; Li, WM; Li, YS; Luo, YF; Wang, YL; Wei, YQ; Xiang, R; Yan, HX; Yang, J; Yang, QY; Yang, SY; Yang, W; Zhang, G; Zhu, JQ1
Deng, Y; Dong, S; Han, W; Han, Y; Li, Z; Liu, S; Luo, Z; Ni, D; Niu, L; Pi, R; Song, L; Sun, D; Wei, Q; Zhao, Y; Zhu, T1
Chen, B; Dai, R; Feng, M; Li, M; Liu, J; Tang, J; Xiao, S; Zhang, X1
Cai, Y; Cao, Z; Han, W; Lu, M; Ran, J; Song, C; Tang, C; Wei, Z; Zhang, G; Zou, H1
Jiang, W; Li, L; Lian, ZX; Liu, QZ; Long, J; Wang, YC; Yan, K; Yang, JB; Zhao, YY; Zhao, ZB1
Alba, G; Carlson, T; Chen, A; Coberly, S; Dai, K; Eksterowicz, J; Hollenback, D; Huard, J; Kamb, A; Keegan, K; Li, C; Li, Z; Liang, L; Liu, L; Lo, MC; Ma, J; McGee, LR; Medina, J; Ngo, R; Orf, J; Quéva, C; Ragains, M; Wang, X; Weidner, M; Wickramasinghe, D; Zhao, S1
Coplin, MA; Donahue, RN; Farsaci, B; Grenga, I; Hodge, JW; Lepone, LM; Molinolo, AA1
De Velasco, MA; Hatanaka, Y; Kura, Y; Minami, T; Nishio, K; Nozawa, M; Oki, T; Ozeki, T; Shimizu, N; Uemura, H; Yamamoto, Y; Yoshikawa, K; Yoshimura, K1
Gao, M; Hua, H; Jiang, Y; Kong, Q; Luo, T; Wang, J; Yin, Y1
Booth, L; Dent, P; Poklepovic, A; Roberts, JL1
Bian, S; Cai, H; Cui, Y; Fan, Y; Liang, J; Sui, J; Sun, Y; Xu, Z; Zhang, X; Zhou, L1
Dabora, SL; Lee, N; Messina, MP; Nobil, AM; Rauktys, AE; Woodrum, CL1
Bouzin, C; Calderon, PB; Charette, N; Danhier, P; Feron, O; Gallez, B; Grégoire, V; Jordan, BF; Karroum, O; Kengen, J; Magat, J; Mignion, L; Sonveaux, P; Starkel, P; Verrax, J1

Other Studies

18 other study(ies) available for sorafenib and Experimental Neoplasms

ArticleYear
Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents.
    European journal of medicinal chemistry, 2015, Jan-27, Volume: 90

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Imidazoles; MCF-7 Cells; Mice; Mice, Nude; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridines; Sorafenib; Structure-Activity Relationship

2015
Design, synthesis and biological evaluation of bis-aryl ureas and amides based on 2-amino-3-purinylpyridine scaffold as DFG-out B-Raf kinase inhibitors.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Amides; Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Purines; Structure-Activity Relationship; Urea

2015
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations.
    European journal of medicinal chemistry, 2015, Jul-15, Volume: 100

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; fms-Like Tyrosine Kinase 3; Humans; Male; Mice; Mice, Inbred ICR; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Point Mutation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles

2015
Combination of 4-anilinoquinazoline, arylurea and tertiary amine moiety to discover novel anticancer agents.
    Bioorganic & medicinal chemistry, 2016, Jan-15, Volume: 24, Issue:2

    Topics: Amines; Aniline Compounds; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Quinazolines; Structure-Activity Relationship; Urea

2016
Design, synthesis, and anticancer properties of isocorydine derivatives.
    Bioorganic & medicinal chemistry, 2017, 12-15, Volume: 25, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; Aporphines; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship

2017
Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Amines; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Structure; Mutation; Neoplasms, Experimental; NIH 3T3 Cells; Proto-Oncogene Proteins c-ret; Structure-Activity Relationship

2018
Novel 2-phenyl-3-(Pyridin-2-yl) thiazolidin-4-one derivatives as potent inhibitors for proliferation of osteosarcoma cells in vitro and in vivo.
    European journal of medicinal chemistry, 2022, Jan-15, Volume: 228

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Osteosarcoma; Pyridines; Structure-Activity Relationship; Thiazolidines

2022
Multifunctional FeS
    Biomaterials science, 2021, Dec-21, Volume: 10, Issue:1

    Topics: Animals; Cell Line, Tumor; Mice; Nanoparticles; Neoplasms, Experimental; Photochemotherapy; Photothermal Therapy; Serum Albumin, Bovine; Sorafenib

2021
Novel NIR-II semiconducting molecule incorporating sorafenib for imaging guided synergetic cancer phototherapy and anti-angiogenic therapy.
    Journal of materials chemistry. B, 2021, 04-14, Volume: 9, Issue:14

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Drug Screening Assays, Antitumor; Humans; Infrared Rays; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Neoplasms, Experimental; Optical Imaging; Photochemotherapy; Semiconductors; Sorafenib

2021
Adaptive immune cells are necessary for the enhanced therapeutic effect of sorafenib-loaded nanoparticles.
    Biomaterials science, 2018, Mar-26, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Homeodomain Proteins; Immunity, Cellular; Lymphocytes; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Polyesters; Polyethylene Glycols; Sorafenib

2018
Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:4

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 4; Dose-Response Relationship, Drug; fms-Like Tyrosine Kinase 3; Heterocyclic Compounds, 3-Ring; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Nude; Naphthyridines; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Sorafenib; U937 Cells; Xenograft Model Antitumor Assays

2014
Immune consequences of decreasing tumor vasculature with antiangiogenic tyrosine kinase inhibitors in combination with therapeutic vaccines.
    Cancer immunology research, 2014, Volume: 2, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Cancer Vaccines; Cell Line, Tumor; Combined Modality Therapy; Female; Flow Cytometry; Humans; Indoles; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sorafenib; Sunitinib; Vaccines, Synthetic

2014
Evaluation of in vivo responses of sorafenib therapy in a preclinical mouse model of PTEN-deficient of prostate cancer.
    Journal of translational medicine, 2015, May-08, Volume: 13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Disease Models, Animal; Everolimus; Genetic Engineering; Homozygote; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Prostatic Neoplasms; PTEN Phosphohydrolase; Signal Transduction; Sorafenib

2015
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
    Oncotarget, 2016, Mar-29, Volume: 7, Issue:13

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Aspirin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Sorafenib; TOR Serine-Threonine Kinases; Up-Regulation; Xenograft Model Antitumor Assays

2016
PDE5 inhibitors enhance the lethality of [pemetrexed + sorafenib].
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Drug Synergism; Humans; Lung Neoplasms; Mice; Neoplasms, Experimental; Niacinamide; Pemetrexed; Phenylurea Compounds; Phosphodiesterase 5 Inhibitors; Sildenafil Citrate; Sorafenib; Xenograft Model Antitumor Assays

2017
Synergistic chemotherapeutic effect of sorafenib-loaded pullulan-Dox conjugate nanoparticles against murine breast carcinoma.
    Nanoscale, 2017, Feb-23, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Female; Glucans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Sorafenib

2017
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models.
    BMC pharmacology, 2009, Apr-15, Volume: 9

    Topics: Animals; Atorvastatin; Benzenesulfonates; Cystadenoma; Disease Models, Animal; Doxycycline; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Heptanoic Acids; Immunosuppressive Agents; Interferon-gamma; Kidney Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Neoplasms, Experimental; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Burden; Tumor Suppressor Proteins

2009
Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1

    Topics: Angiogenesis Inducing Agents; Animals; Apoptosis; Benzamides; Blotting, Western; Diphenylamine; Electron Spin Resonance Spectroscopy; Fibrosarcoma; Glutathione; Liver Neoplasms, Experimental; Mice; Neoplasms, Experimental; Niacinamide; Oxygen Consumption; Phenylurea Compounds; Protein Kinase Inhibitors; Radiation Tolerance; Sorafenib

2012