sophocarpine has been researched along with Disease Models, Animal in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Du, X; Hu, K; Li, Y; Liu, Q; Liu, Y; Sun, T; Wang, C; Zhang, H; Zhi, W; Zong, S | 1 |
| Hao, Q; Ma, C; Shen, Y; Ye, JY; Zhang, Z; Zong, Y | 1 |
| Chen, G; Deng, X; Li, Y; Liu, W; Shi, Y; Sun, Y; Wang, F; Wu, W; Zeng, Q; Zhang, B; Zhou, L | 1 |
| Cao, L; Chen, X; Cui, J; Hu, H; Liu, C; Pan, P; Su, J; Weng, W; Zhao, Q; Zhi, X; Zhou, Q | 1 |
| Chen, ZX; Heng, BC; Hu, B; Jiang, S; Meng, JH; Parkman, VA; Shen, WL; Shi, ZL; Wu, HB; Yan, SG; Yang, YT; Yu, W; Zhao, CC; Zhou, CH; Zhu, HX | 1 |
| Hong, H; Li, X; Liu, Z; Luo, C; Wang, M; Yang, R | 1 |
| Huang, H; Kang, X; Pan, J; Wu, D; Yu, J; Zhang, X; Zhu, X | 1 |
| Chen, YX; Fang, JQ; Qian, H; Sheng, X; Shi, J; Song, CY; Wang, Y; Zeng, X; Zhang, Y; Zheng, JM | 1 |
| Deng, G; Guo, M; Li, C; Qiu, C; Wang, D; Xu, N; Yang, S; Zhang, Z | 1 |
| Fu, C; Gao, Y; Li, B; Li, C; Li, G; Li, M; Zhu, X | 1 |
| Chen, SW; Chen, YX; Hu, PF; Ning, BF; Shi, J; Song, CY; Xie, WF; Zeng, X; Zheng, ZW | 1 |
| Bin, W; Bing, L; Weiqiao, Z; Xiaojie, L; Yifeng, M; Yongming, Q | 1 |
13 other study(ies) available for sophocarpine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Proteome profiling reveals the efficacy and targets of sophocarpine against asthma.
Topics: Alkaloids; Allergens; Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Disease Models, Animal; Female; Humans; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Targeted Therapy; Ovalbumin; Proteome; Th2 Cells | 2021 |
Sophocarpine Attenuates Cognitive Impairment and Promotes Neurogenesis in a Mouse Model of Alzheimer's Disease.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Disease Models, Animal; Mice; Mice, Transgenic; Neurogenesis | 2021 |
Targeting miR-21 with Sophocarpine Inhibits Tumor Progression and Reverses Epithelial-Mesenchymal Transition in Head and Neck Cancer.
Topics: Alkaloids; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice; MicroRNAs; Mutation; p38 Mitogen-Activated Protein Kinases; Xenograft Model Antitumor Assays | 2017 |
Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis.
Topics: Acetates; Alkaloids; Animals; Benzopyrans; Bone Density; Bone Density Conservation Agents; Bone Marrow Cells; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Macrophage Colony-Stimulating Factor; Mesenchymal Stem Cells; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoclasts; Osteogenesis; Osteoporosis, Postmenopausal; Ovariectomy; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Primary Cell Culture; Proto-Oncogene Proteins c-akt; RANK Ligand; Ribosomal Proteins; Signal Transduction | 2017 |
Sophocarpine attenuates wear particle-induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF-κB signalling pathway in a rat model.
Topics: Alkaloids; Animals; Bone Resorption; Disease Models, Animal; Male; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Prosthesis Failure; RANK Ligand; Rats; Rats, Sprague-Dawley; Signal Transduction; Sophora | 2018 |
Sophocarpine attenuates murine lupus nephritis via inhibiting NLRP3 inflammasome and NF-κB activation.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antigen-Antibody Complex; Cytokines; Disease Models, Animal; Female; Humans; Inflammation Mediators; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction | 2018 |
The protective effect of sophocarpine in osteoarthritis: An in vitro and in vivo study.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Disease Models, Animal; Female; Humans; Inflammation Mediators; Interleukin-1beta; Male; Osteoarthritis; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sophora | 2019 |
Sophocarpine attenuates toll-like receptor 4 in steatotic hepatocytes to suppress pro-inflammatory cytokines synthesis.
Topics: Alkaloids; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Expression; Hepatocytes; Inflammation Mediators; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oleic Acid; Polymerase Chain Reaction; Rats, Sprague-Dawley; Signal Transduction; Sophora; Toll-Like Receptor 4; Up-Regulation | 2015 |
RETRACTED: Sophocarpine displays anti-inflammatory effect via inhibiting TLR4 and TLR4 downstream pathways on LPS-induced mastitis in the mammary gland of mice.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mammary Glands, Human; Mastitis; Mice; Mice, Inbred BALB C; NF-kappa B; Signal Transduction; Sophora; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Anti-nociceptive and anti-inflammatory activity of sophocarpine.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Inflammation; Male; Mice; Mice, Inbred Strains; Pain; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Sophora; Xylenes | 2009 |
Sophocarpine alleviates non-alcoholic steatohepatitis in rats.
Topics: Adipokines; Alkaloids; Animals; Anti-Inflammatory Agents; Cytokines; Cytoprotection; Disease Models, Animal; Down-Regulation; Fatty Liver; Inflammation Mediators; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Organ Size; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors; Transaminases | 2011 |
Neuroprotective effect of sophocarpine against transient focal cerebral ischemia via down-regulation of the acid-sensing ion channel 1 in rats.
Topics: Acid Sensing Ion Channels; Alkaloids; Animals; Apoptosis; Brain Infarction; Brain Ischemia; Disease Models, Animal; Down-Regulation; Infarction, Middle Cerebral Artery; Male; Nerve Tissue Proteins; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Channels; Treatment Outcome | 2011 |