somatotropin-(177-191) and Weight-Gain

somatotropin-(177-191) has been researched along with Weight-Gain* in 1 studies

Other Studies

1 other study(ies) available for somatotropin-(177-191) and Weight-Gain

Article	Year
Reduction of cumulative body weight gain and adipose tissue mass in obese mice: response to chronic treatment with synthetic hGH 177-191 peptide. Biochemistry and molecular biology international, 1994, Volume: 33, Issue:5 The effects of long-term treatment of C57BL/6J (ob/ob) mice with a synthetic carboxylterminal sequence of human growth hormone, hGH 177-191, were investigated. Results indicate that the hGH 177-191 reduced the cumulative body weight gain, and decreased the adipose tissue mass. The lipogenesis in adipose tissues was significantly inhibited by the treatment with hGH 177-191. These findings support the suggestion that hGH 177-191 is the functional domain of hGH for the antilipogenic actions of the intact hormone both in vivo and in vitro. The hGH 177-191 peptide has the potential to be an effective compound for the treatment of human obesity and for the improvement of meat qualities in farm animals. Topics: Adipose Tissue; Amino Acid Sequence; Animals; Cholesterol; Eating; Female; Growth Hormone; Lipids; Male; Mice; Mice, Obese; Molecular Sequence Data; Obesity; Peptide Fragments; Sex Factors; Triglycerides; Weight Gain	1994

Article

Year

Reduction of cumulative body weight gain and adipose tissue mass in obese mice: response to chronic treatment with synthetic hGH 177-191 peptide.

Biochemistry and molecular biology international, 1994, Volume: 33, Issue:5

The effects of long-term treatment of C57BL/6J (ob/ob) mice with a synthetic carboxylterminal sequence of human growth hormone, hGH 177-191, were investigated. Results indicate that the hGH 177-191 reduced the cumulative body weight gain, and decreased the adipose tissue mass. The lipogenesis in adipose tissues was significantly inhibited by the treatment with hGH 177-191. These findings support the suggestion that hGH 177-191 is the functional domain of hGH for the antilipogenic actions of the intact hormone both in vivo and in vitro. The hGH 177-191 peptide has the potential to be an effective compound for the treatment of human obesity and for the improvement of meat qualities in farm animals.

Topics: Adipose Tissue; Amino Acid Sequence; Animals; Cholesterol; Eating; Female; Growth Hormone; Lipids; Male; Mice; Mice, Obese; Molecular Sequence Data; Obesity; Peptide Fragments; Sex Factors; Triglycerides; Weight Gain

1994