Page last updated: 2024-08-18

soman and Poisoning

soman has been researched along with Poisoning in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19905 (8.62)18.7374
1990's38 (65.52)18.2507
2000's9 (15.52)29.6817
2010's5 (8.62)24.3611
2020's1 (1.72)2.80

Authors

AuthorsStudies
Armstrong, SJ; Cadieux, CL; Capacio, BR; Cerasoli, DM; Hodgins, SM; Kasten, SA; Lee-Stubbs, RB; Lenz, DE; Otto, TC; Reeves, TE1
Bird, M; Docx, CJ; Fairhall, SJ; Flint, DP; Green, AC; Poole, SJC; Price, ME; Rice, H; Tattersall, JEH; Timperley, CM; Whiley, L1
Berend, S; Kuca, K; Radić, B; Vrdoljak, AL1
Adler, M; Akkerman, M; Albuquerque, EX; Aracava, Y; Pereira, EF1
Carpentier, P; Dorandeu, F; Foquin, A1
Langston, JL; Myers, TM1
Bird, M; Chad, JE; Green, AC; Price, M; Tattersall, JE; Timperley, CM; Turner, SR1
Cho, Y; Ha, YC; Hur, GH; Kim, WS1
Couzin, J1
Cabal, J; Dohnal, V; Kuca, K; Sevelová-Bartosová, L1
Hassel, B1
Adler, M; Albuquerque, EX; Aracava, Y; Fawcett, WP; Hamilton, TA; Kan, RK; Oliveira, M; Pereira, EF; Randall, WR; Romano, JA1
Kassa, J6
Wetherell, JR1
Algers, G; Fredriksson, SA; Karlsson, B; Sellström, A1
Ashani, Y; Doctor, BP; Grunwald, J; Raveh, L1
Koplovitz, I; Stewart, JR1
Kaveeshwar, U; Purshottam, T1
Szinicz, L; Worek, F1
Sket, D1
Blick, DW; Kerenyi, SZ; Miller, SA; Murphy, MR1
Bajgar, J; Krs, O; Pospísilová, B; Slízová, D1
Bajgar, J; Kassa, J1
Bruijnzeel, PL; Busker, RW; Melchers, BP; van Helden, HP1
Baubichon, D; Blanchet, G; Brochier, G; Clarencon, D; Galonnier, M; Lallement, G; Mestries, JC1
Bajgar, J1
Ashani, Y; Cohen, E; Grauer, E; Grunwald, J; Raveh, L1
Allon, N; Ashani, Y; Cohen, E; Gilat, E; Grunwald, J; Raveh, L1
Bruijnzeel, PL; Groen, B; Moor, E; van Helden, HP; Westerink, BH1
Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Peoc'h, M1
Kassa, J; Koupilová, M1
Byers, CE; Capacio, BR; McDonough, JH; Whalley, CE1
Tattersall, JE; Wood, SJ1
Clason-van der Wiel, HJ; Nickolson, VJ; Wolthuis, OL1
Löffler, W; Schenk, J; Weger, N1
Anderson, DR; Harris, LW; Lennox, WJ; Murrow, ML; Solana, RP; Wade, JV1
Anderson, DR; Harris, LW; Lennox, WJ; Woodard, CL1
Bajgar, J; Skopec, F2
Boulet, CA; Hand, BT; Hansen, AS; Lundy, PM1
Holmstedt, B; Karlén, B; Kimland, M; Nordgren, I; Palmér, L1
Das Gupta, S; Dube, SN; Jaiswal, DK; Kumar, D; Sikder, AK; Sikder, N1
Castro, CA; De La Hoz, DM; Doctor, BP; Gentry, MK; Gold, MB; Maxwell, DM; Solana, RP; Wolfe, AD1
Busker, RW; de Lange, J; Melchers, BP; van der Wiel, HJ; van Helden, HP; Wolthuis, OL1
Capacio, BR; Koviak, TA; Shih, TM1
Bajgar, J; Fusek, J; Jakl, A; Patocka, J1
Bottoms, GD; Fessler, JF; Johnson, M; Pfeifer, CA; Roesel, OF; Voorhees, WD1
French, MC; Wetherell, JR1
Broomfield, CA; Castro, CA; Finger, AV; Lenz, DE; Maxwell, DM; Solana, RP1
Ashani, Y; Doctor, BP; Levy, D; Raveh, L; Shapira, S; Wolfe, AD1
Brzin, M; Dekleva, A; Sket, D; Sketelj, J1
Okonek, S1
Meeter, E1

Reviews

2 review(s) available for soman and Poisoning

ArticleYear
Pharmacological effects of oximes: how relevant are they?
    Archives of toxicology, 1996, Volume: 70, Issue:12

    Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Pyridinium Compounds; Receptors, Cholinergic; Respiration; Soman; Synaptic Transmission

1996
Present views on toxidynamics of soman poisoning.
    Acta medica (Hradec Kralove), 1996, Volume: 39, Issue:3

    Topics: Animals; Chemical Warfare Agents; Humans; Poisoning; Soman

1996

Other Studies

56 other study(ies) available for soman and Poisoning

ArticleYear
Butyrylcholinesterase, a stereospecific in vivo bioscavenger against nerve agent intoxication.
    Biochemical pharmacology, 2020, Volume: 171

    Topics: Animals; Area Under Curve; Butyrylcholinesterase; Chemical Warfare Agents; Guinea Pigs; Humans; Injections, Intramuscular; Injections, Intravenous; Lethal Dose 50; Male; Metabolic Clearance Rate; Nerve Agents; Neuroprotective Agents; Organothiophosphorus Compounds; Poisoning; Soman; Stereoisomerism

2020
Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig.
    Toxicology letters, 2016, Feb-26, Volume: 244

    Topics: Animals; Anticonvulsants; Antidotes; Atropine; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Lethal Dose 50; Male; Muscarinic Antagonists; Nerve Agents; Nicotinic Antagonists; Poisoning; Pyridinium Compounds; Soman

2016
New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning.
    Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3

    Topics: Animals; Chemical Warfare Agents; Enzyme Reactivators; Humans; In Vitro Techniques; Lethal Dose 50; Male; Mice; Mice, Inbred BALB C; Organophosphate Poisoning; Organophosphates; Oximes; Poisoning; Pyridinium Compounds; Soman

2008
Effectiveness of donepezil, rivastigmine, and (+/-)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamine.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Acetylcholinesterase; Alkaloids; Animals; Antidotes; Chemical Warfare Agents; Donepezil; Dose-Response Relationship, Drug; Galantamine; Guinea Pigs; Indans; Lethal Dose 50; Male; Phenylcarbamates; Piperidines; Poisoning; Rivastigmine; Sesquiterpenes; Soman; Time Factors; Toxicity Tests, Acute

2009
Hypertonic mannitol in mice poisoned by a convulsive dose of soman: antilethal activity without neuroprotection.
    Toxicology, 2010, Jan-31, Volume: 268, Issue:1-2

    Topics: Animals; Convulsants; Male; Mannitol; Mice; Osmolar Concentration; Poisoning; Seizures; Soman

2010
Diet composition modifies the toxicity of repeated soman exposure in rats.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: Animal Nutritional Physiological Phenomena; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Chemical Warfare Agents; Choline; Cholinesterase Inhibitors; Diet; Diet, Ketogenic; Dietary Carbohydrates; Glucose; Lethal Dose 50; Male; Nutritional Status; Poisoning; Rats; Rats, Sprague-Dawley; Soman; Time Factors

2011
Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist.
    Toxicology letters, 2011, Sep-25, Volume: 206, Issue:1

    Topics: Animals; Cell Line, Tumor; Chemical Warfare Agents; Diaphragm; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ion Channel Gating; Male; Muscle Contraction; Nicotinic Antagonists; Organophosphate Poisoning; Organophosphates; Poisoning; Pyridinium Compounds; Sarin; Soman

2011
Minimum effective drug concentrations of a transdermal patch system containing procyclidine and physostigmine for prophylaxis against soman poisoning in rhesus monkeys.
    Environmental toxicology and pharmacology, 2012, Volume: 33, Issue:1

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Muscarinic Antagonists; Oximes; Physostigmine; Poisoning; Procyclidine; Pyridinium Compounds; Soman; Transdermal Patch

2012
Clinical trials. New rule triggers debate over best way to test drugs.
    Science (New York, N.Y.), 2003, Mar-14, Volume: 299, Issue:5613

    Topics: Advisory Committees; Animals; Biological Warfare; Chemical Warfare Agents; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; Humans; Military Personnel; Persian Gulf Syndrome; Poisoning; Pyridostigmine Bromide; Soman; United States; United States Food and Drug Administration; Vaccines

2003
Cyclodextrines as functional agents for decontamination of the skin contaminated by nerve agents.
    Acta medica (Hradec Kralove), 2004, Volume: 47, Issue:2

    Topics: Animals; beta-Cyclodextrins; Chemical Warfare Agents; Cholinesterase Inhibitors; Cyclodextrins; Decontamination; Male; Poisoning; Rats; Rats, Wistar; Skin Absorption; Soman

2004
Nicotinic mechanisms contribute to soman-induced symptoms and lethality.
    Neurotoxicology, 2006, Volume: 27, Issue:4

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Behavior, Animal; Chemical Warfare Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperkinesis; Lethal Dose 50; Mecamylamine; Mice; Muscarinic Antagonists; Muscle Rigidity; Nicotine; Nicotinic Antagonists; Poisoning; Scopolamine; Soman; Time Factors; Tremor

2006
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-29, Volume: 103, Issue:35

    Topics: Acetylcholinesterase; Alkaloids; Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Lethal Dose 50; Neurons; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Poisoning; Pyridostigmine Bromide; Sarin; Sesquiterpenes; Soman; Time Factors

2006
Comparison of efficacy of two oximes (HI-6 and obidoxime) in soman poisoning in rats.
    Toxicology, 1995, Aug-25, Volume: 101, Issue:3

    Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Cholinesterase Reactivators; Cortisone; Female; Liver; Obidoxime Chloride; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tyrosine Transaminase

1995
Continuous administration of low dose rates of physostigmine and hyoscine to guinea-pigs prevents the toxicity and reduces the incapacitation produced by soman poisoning.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:12

    Topics: Acetylcholinesterase; Animals; Cerebellum; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Guinea Pigs; Hippocampus; Infusion Pumps, Implantable; Male; Medulla Oblongata; Mesencephalon; Osmosis; Physostigmine; Poisoning; Scopolamine; Soman

1994
The protective effect of nimodipine, a calcium antagonist, and its influence on soman clearance in the anaesthetized rabbit.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:2

    Topics: Acetylcholinesterase; Anesthesia; Animals; Calcium; Cholinesterases; Gas Chromatography-Mass Spectrometry; Injections, Intraperitoneal; Nimodipine; Poisoning; Rabbits; Soman; Tissue Distribution

1994
Huperzine A as a pretreatment candidate drug against nerve agent toxicity.
    Life sciences, 1994, Volume: 54, Issue:14

    Topics: Acetylcholinesterase; Alkaloids; Animals; Antidotes; Binding Sites; Brain; Cholinesterase Inhibitors; Injections, Intraperitoneal; Kinetics; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Physostigmine; Poisoning; Sesquiterpenes; Soman; Time Factors

1994
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
    Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms

1994
Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats.
    Indian journal of experimental biology, 1993, Volume: 31, Issue:4

    Topics: Acetylcholinesterase; Animals; Cholinesterases; Dichlorvos; Dose-Response Relationship, Drug; Male; Poisoning; Rats; Rats, Wistar; Soman

1993
Atropine and oxime treatment in lethal soman poisoning of anaesthetized guinea-pigs: HLö 7 dimethanesulfonate versus HI 6 dichloride.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:1

    Topics: Acetylcholinesterase; Anesthesia; Animals; Antidotes; Atropine; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Female; Guinea Pigs; Hemodynamics; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Respiration; Soman

1993
Efficacy of antidotes against soman poisoning in female physostigmine-protected rats.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:1

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Diazepam; Drug Therapy, Combination; Female; Muscles; Oximes; Physostigmine; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Soman

1993
Efficacy of physostigmine as a pretreatment for organophosphate poisoning.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:2

    Topics: Animals; Cholinesterases; Lethal Dose 50; Male; Physostigmine; Poisoning; Rats; Rats, Sprague-Dawley; Soman

1993
Changes in microvascularization of some rat organs following soman poisoning.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1995, Volume: 38, Issue:3

    Topics: Adrenal Glands; Animals; Brain; Corrosion Casting; Kidney; Male; Microcirculation; Microscopy, Electron, Scanning; Poisoning; Rats; Rats, Wistar; Soman; Thymus Gland

1995
[Comparison of the effect of HI-6 oxime and its derivatives in combination with benactyzine on cholinergic and stress effects of soman in rats].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 1996, Volume: 45, Issue:3

    Topics: Animals; Antidotes; Benactyzine; Cholinesterase Inhibitors; Cholinesterases; Corticosterone; Drug Therapy, Combination; Male; Oximes; Parasympatholytics; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tyrosine Transaminase

1996
The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats.
    Human & experimental toxicology, 1996, Volume: 15, Issue:5

    Topics: Animals; Antidotes; Benactyzine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Corticosterone; Diaphragm; Drug Therapy, Combination; Liver; Male; Muscarinic Antagonists; Obidoxime Chloride; Oximes; Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl; Tyrosine Transaminase

1996
Efficacy of atropine/pralidoxime/diazepam or atropine/HI-6/prodiazepam in primates intoxicated by soman.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2

    Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electrocardiography; Electroencephalography; Macaca fascicularis; Male; Oximes; Poisoning; Pralidoxime Compounds; Prodrugs; Pyridinium Compounds; Soman

1997
The stoichiometry of protection against soman and VX toxicity in monkeys pretreated with human butyrylcholinesterase.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Animals; Behavior, Animal; Biological Availability; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Humans; Injections, Intramuscular; Injections, Intravenous; Lethal Dose 50; Macaca mulatta; Models, Biological; Organothiophosphorus Compounds; Poisoning; Random Allocation; Soman; Spatial Behavior; Statistics as Topic

1997
[Comparison of the effect of selected cholinesterase reactivators combined with atropine on soman and fosdrin toxicity in mice].
    Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 1995, Volume: 38, Issue:1

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Insecticides; Male; Mevinphos; Mice; Poisoning; Soman

1995
[The effect of pharmacologic prophylaxis with Panpal on acetylcholinesterase activity in the diaphragm and various parts of the brain in rats during treated and untreated Soman poisoning].
    Casopis lekaru ceskych, 1998, May-18, Volume: 137, Issue:10

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Benactyzine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Drug Combinations; Male; Oximes; Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl

1998
A comparison of the efficacy of new asymmetric bispyridinium oxime BI-6 with other oximes (obidoxime, HI-6) against soman in rats.
    Human & experimental toxicology, 1998, Volume: 17, Issue:6

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Drug Therapy, Combination; Liver; Male; Obidoxime Chloride; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Soman; Tyrosine Transaminase

1998
Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 43, Issue:2

    Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Guinea Pigs; Humans; Inhalation Exposure; Male; Poisoning; Premedication; Respiration; Soman

1998
New generic approach to the treatment of organophosphate poisoning: adenosine receptor mediated inhibition of ACh-release.
    Drug and chemical toxicology, 1998, Volume: 21 Suppl 1

    Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Chemistry; Cholinesterase Inhibitors; Dinucleoside Phosphates; Injections, Intramuscular; Injections, Subcutaneous; Poisoning; Purinergic P1 Receptor Agonists; Rats; Soman; Survival Rate; Time Factors

1998
Acute soman poisoning in primates neither pretreated nor receiving immediate therapy: value of gacyclidine (GK-11) in delayed medical support.
    Archives of toxicology, 1999, Volume: 73, Issue:2

    Topics: Animals; Anticonvulsants; Antidotes; Atropine; Brain; Cerebellum; Cerebral Cortex; Chemical Warfare Agents; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Therapy, Combination; Electrocardiography; Excitatory Amino Acid Antagonists; Haplorhini; Macaca fascicularis; Male; Piperidines; Poisoning; Pralidoxime Compounds; Seizures; Soman; Time Factors

1999
Neuroprotective effects of antidotes in soman-poisoned rats.
    Acta medica (Hradec Kralove), 1999, Volume: 42, Issue:4

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Male; Nervous System; Obidoxime Chloride; Poisoning; Rats; Rats, Wistar; Soman

1999
[Effect of diazepam on the effectiveness of antidote therapy in eliminating the acute lethal effects of soman in mice].
    Casopis lekaru ceskych, 2001, Volume: 140, Issue:16

    Topics: Acute Disease; Animals; Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Male; Mice; Mice, Inbred Strains; Oximes; Poisoning; Pyridinium Compounds; Soman

2001
Intramuscular diazepam pharmacokinetics in soman-exposed guinea pigs.
    Journal of applied toxicology : JAT, 2001, Volume: 21 Suppl 1

    Topics: Adsorption; Animals; Anticonvulsants; Chemical Warfare Agents; Diazepam; Dose-Response Relationship, Drug; Guinea Pigs; Injections, Intramuscular; Male; Military Medicine; Poisoning; Soman

2001
An improved brain slice model of nerve agent-induced seizure activity.
    Journal of applied toxicology : JAT, 2001, Volume: 21 Suppl 1

    Topics: Animals; Anticonvulsants; Chemical Warfare Agents; Culture Techniques; Disease Models, Animal; Electrophysiology; Entorhinal Cortex; Guinea Pigs; Hippocampus; Male; Poisoning; Seizures; Soman

2001
Further studies on the therapy of organophosphorous anti-cholinesterase intoxication with veratrinic compounds; the role of calcium.
    European journal of pharmacology, 1975, Volume: 30, Issue:2

    Topics: Animals; Anthracenes; Atropine; Calcium; Carboxylic Acids; Cholinesterase Inhibitors; Edetic Acid; Male; Muscles; Organophosphate Poisoning; Poisoning; Postmortem Changes; Rats; Rats, Inbred Strains; Respiratory Paralysis; Soman; Veratrine

1975
Therapeutic effects of HS-3, HS-6, benactyzine, and atropine in soman poisoning of dogs.
    Archives of toxicology, 1976, Sep-15, Volume: 36, Issue:1

    Topics: Animals; Antidotes; Aspartate Aminotransferases; Atropine; Benactyzine; Creatine Kinase; Dogs; Drug Administration Schedule; Drug Therapy, Combination; Kinetics; Male; Organophosphate Poisoning; Poisoning; Pralidoxime Compounds; Soman

1976
Successful pretreatment/therapy of soman, sarin and VX intoxication.
    Drug and chemical toxicology, 1992, Volume: 15, Issue:4

    Topics: Animals; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Organothiophosphorus Compounds; Phenylpropionates; Physostigmine; Poisoning; Sarin; Soman; Trihexyphenidyl; Tropanes

1992
The effect of pyridostigmine pretreatment on oxime efficacy against intoxication by soman or VX in rats.
    Drug and chemical toxicology, 1992, Volume: 15, Issue:4

    Topics: Animals; Antidotes; Cholinesterase Inhibitors; Male; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Soman

1992
Changes of acetylcholinesterase activity in hepatectomized rats following soman poisoning.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1992, Volume: 35, Issue:3

    Topics: Acetylcholinesterase; Animals; Hepatectomy; Male; Poisoning; Rats; Rats, Wistar; Soman

1992
Liver and brain DNA contents in acute soman intoxication.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1992, Volume: 35, Issue:3

    Topics: Acute Disease; Animals; Brain Chemistry; DNA; Female; Liver; Poisoning; Rats; Rats, Wistar; Soman

1992
Comparison of several oximes against poisoning by soman, tabun and GF.
    Toxicology, 1992, Volume: 72, Issue:1

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Soman

1992
Intoxications with anticholinesterases: effect of different combinations of antidotes on the dynamics of acetylcholine in mouse brain.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:5 Pt 1

    Topics: Acetylcholine; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Drug Therapy, Combination; Male; Mice; Oximes; Poisoning; Pyridinium Compounds; Soman

1992
Therapeutic efficacy of bis-pyridinium oximes against diisopropyl fluorophosphate (DFP) and soman intoxication in rodents.
    Die Pharmazie, 1992, Volume: 47, Issue:1

    Topics: Animals; Cholinesterase Reactivators; Isoflurophate; Mice; Neuromuscular Blocking Agents; Oximes; Phrenic Nerve; Poisoning; Pyridinium Compounds; Rats; Respiratory Muscles; Soman

1992
Protection of rhesus monkeys against soman and prevention of performance decrement by pretreatment with acetylcholinesterase.
    Toxicology and applied pharmacology, 1992, Volume: 115, Issue:1

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Lethal Dose 50; Macaca mulatta; Male; Poisoning; Premedication; Soman

1992
Therapeutic efficacy of HI-6 in soman-poisoned marmoset monkeys.
    Toxicology and applied pharmacology, 1992, Volume: 115, Issue:1

    Topics: Acetylcholinesterase; Animals; Atropine; Brain; Butyrylcholinesterase; Callithrix; Cholinesterase Inhibitors; Cholinesterases; Chromatography, High Pressure Liquid; Diaphragm; Diazepam; Enzyme Activation; Oximes; Poisoning; Pyridinium Compounds; Soman

1992
Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms.
    Neuroscience and biobehavioral reviews, 1991,Fall, Volume: 15, Issue:3

    Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidotes; Atropine; Brain Chemistry; Choline; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Gas Chromatography-Mass Spectrometry; Male; Oximes; Parasympatholytics; Poisoning; Pyridinium Compounds; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Seizures; Soman

1991
Efficacy of various pretreatment and therapy regimens against soman lethality in mice.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1991, Volume: 34, Issue:3

    Topics: Animals; Atropine; Diazepam; Female; Male; Mice; Obidoxime Chloride; Poisoning; Pyridostigmine Bromide; Soman; Trihexyphenidyl; Trimedoxime

1991
The effects of soman poisoning in combination with hypovolemic shock.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:4

    Topics: Acetylcholinesterase; Animals; Blood Cell Count; Blood Chemical Analysis; Blood Circulation; Brain; Butyrylcholinesterase; Dogs; Erythrocytes; Female; Hemodynamics; Male; Poisoning; Respiration; Respiratory Muscles; Shock; Soman

1991
A comparison of the decarbamoylation rates of physostigmine-inhibited plasma and red cell cholinesterases of man with other species.
    Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3

    Topics: Acetylcholinesterase; Animals; Callitrichinae; Cholinesterase Inhibitors; Cholinesterases; Erythrocyte Volume; Erythrocytes; Female; Guinea Pigs; Humans; Macaca mulatta; Male; Physostigmine; Plasma; Plasma Cells; Poisoning; Soman; Species Specificity; Time Factors

1991
Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Animals; Behavior, Animal; Butyrylcholinesterase; Learning; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Poisoning; Sarin; Soman

1991
Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice.
    Biochemical pharmacology, 1991, Jan-01, Volume: 41, Issue:1

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Interactions; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Poisoning; Quinolinium Compounds; Soman; Time Factors

1991
Attenuation of soman-induced lesions of skeletal muscle by acetylcholinesterase reactivating and non-reactivating antidotes.
    Acta neuropathologica, 1989, Volume: 79, Issue:2

    Topics: Acetylcholinesterase; Animals; Antidotes; Male; Muscles; Organophosphate Poisoning; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Inbred Strains; Soman

1989
[Gaschromatographic studies on direct reaction of soman and paraoxon with Pyridinium aldoximes in vitro].
    Archiv fur Toxikologie, 1972, Volume: 29, Issue:3

    Topics: Antidotes; Blood; Chemical Phenomena; Chemistry; Cholinesterase Reactivators; Chromatography, Gas; Humans; Hydrolysis; Insecticides; Kinetics; Nitrophenols; Obidoxime Chloride; Oximes; Paraoxon; Poisoning; Pyridinium Compounds; Soman; Time Factors

1972
Investigation of the rapid recovery of rat thermoregulation from soman poisoning.
    European journal of pharmacology, 1973, Volume: 24, Issue:1

    Topics: Animals; Body Temperature Regulation; Carbachol; Cerebral Ventricles; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hypothalamus; Injections; Male; Organophosphate Poisoning; Poisoning; Rats; Soman; Time Factors

1973