solufenum and Hemolysis

solufenum has been researched along with Hemolysis* in 1 studies

Other Studies

1 other study(ies) available for solufenum and Hemolysis

ArticleYear
Comparison of different ibuprofen-amino acid compounds with respect to emulsifying and cytotoxic properties.
    International journal of pharmaceutics, 2004, Apr-15, Volume: 274, Issue:1-2

    Sodium ibuprofen (Ibu-Na) and different ibuprofen-amino acid compounds, lysinate (Ibu-Lys), arginate (Ibu-Arg) and histidinate (Ibu-His), were evaluated for emulsifying, haemolytic and cytotoxic properties. The highest reduction of surface tension was obtained with Ibu-Lys which shows good emulsifying qualities. At the same time, Ibu-Lys reveals the highest haemolytic activity and affects porcine cornea integrity. However, incorporation of Ibu-Lys into an emulsion system significantly decreases haemolysis. On the contrary Ibu-Arg, which shows a lower surface tension reduction, allows, unlike Ibu-Na and Ibu-His, for comparably stable emulsions with comparable erythrocyte damage.

    Topics: Adult; Animals; Arginine; Cornea; Drug Combinations; Drug Stability; Emulsifying Agents; Emulsions; Erythrocytes; Hemolysis; Humans; Ibuprofen; Lysine; Male; Surface Tension; Swine

2004