solanesol has been researched along with Disease-Models--Animal* in 1 studies
1 other study(ies) available for solanesol and Disease-Models--Animal
| Article | Year |
|---|---|
Novel class of hybrid natural products as antidiabetic agents.
A number of O-alkylated xanthone, carbazoles and coumarins have been synthesised and screened for their in vitro anti-diabetic activity, such as glucose-6-phosphatase, glycogen phosphorylase and alpha glucosidase inhibitors. Compounds which were showing significant percentage inhibition were also tested for in vivo anti-hyperglycemic activity in sucrose loaded normal and streptozotocin (STZ)-induced diabetic rats. These compounds show 22.1, 24.4 and 26.7% and 20.8, 25.0, 20.5% lowering in sucrose loaded normal rats and STZ-induced diabetic rats at a dose of 100 mg kg(-1). Topics: Animals; Biological Products; Carbazoles; Coumarins; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose-6-Phosphatase; Glycogen Phosphorylase; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Rats; Streptozocin; Terpenes; Xanthones | 2009 |