Page last updated: 2024-08-25

sofosbuvir and Pregnancy

sofosbuvir has been researched along with Pregnancy in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (35.29)24.3611
2020's11 (64.71)2.80

Authors

AuthorsStudies
Cao, Z; Chen, Z; Gao, D; Khan, IM; Luo, L; Tong, X; Wang, Y; Xu, T; Zhang, D; Zhang, L; Zhang, M; Zhang, Y1
Chen, ZM; Cui, GL; Dong, XP; Ji, F; Lv, J; Wang, B; Yu, ZJ; Zeng, QL; Zhang, HX1
Gowda, C; Honegger, JR1
Hon, KLE; Leung, AKC; Sridhar, S; Wong, AHC1
Abdel-Aziz, MM; Hafez, HA; Kamel, MA; Khafaga, RHM; Mahmoud, SA; Shaker, SA1
Alhmoud, JF; Hafez, HA; Kamel, MA; Khafaga, RHM; Mahmoud, SA; Shaker, SA1
Mandimika, C; Ogbuagu, O1
Alves, AMB; Andrade, MCR; Bentes, GA; Bottino, FO; Castro, MP; Fonseca, LB; Freire, MS; Gardinali, NR; Kugelmeier, T; Lima, SMB; Linhares, JHR; Lopes, CAA; Marchevsky, RS; Melgaço, JG; Miranda, EH; Moran, J; Motta, MCVA; Nudelman, RF; Oliveira, JM; Pelajo-Machado, M; Perea, JAS; Pereira, HM; Pinto, DP; Pinto, MA; Salvador Castro Faria, SB; Sarges, K; Schmidt-Chanasit, J; Silva, ACA; Silva, MCC; Silva, SA; Soares-Bezerra, RJ; Soriano, A; Souza, TML; Trindade, GF; Vilhena, LS1
Burger, DM; Colbers, A; Drenth, JPH; Freriksen, JJM; Greupink, R; Meijerhof, M; Russel, FGM; van Drongelen, J1
Bogen, DL; Bunge, KE; Chappell, CA; Gaggar, A; Hillier, SL; Kirby, BJ; Krans, EE; Macio, IS; Meyn, LA; Scarsi, KK; Suri, V1
Antala, S; Grobman, WA; Jhaveri, R; Murphy, M; Shah, SK; Yee, LM1
AbdAllah, M; Abdel-Razek, W; Alalfy, M; Alboraie, M; Ammar, I; Doss, W; El Akel, W; El-Bendary, M; El-Sayed, MH; El-Serafy, M; Elbaz, T; Esmat, G; Gomaa, A; Hassany, M; Hefny, Z; Kamal, E; Okasha, A; Shaaban, E1
Fraser, H; Havens, JR; Hoven, A; Lofwall, M; Schaninger, T; Staton, M; Vickerman, P; Walsh, SL; Young, AM1
Goebel, S; Kalkeri, R; Koide, F; Ptak, R; Snyder, B1
Brown, RS; Camus, G; Copans, A; Ghali, P; Guyer, B; Haubrich, R; Kang, M; Luetkemeyer, AF; Mantry, PS; Ni, L; Rossaro, L; Satapathy, SK; Shen, X; Tam, E1
Cervino, L; Hynicka, LM1
Domalakes, E; He, L; Lee, GT; Mason, CW; Parrott, J; Pfeifer, E; Zhou, H1

Reviews

2 review(s) available for sofosbuvir and Pregnancy

ArticleYear
Defer no more: advances in the treatment and prevention of chronic hepatitis C virus infection in children.
    Current opinion in infectious diseases, 2022, 10-01, Volume: 35, Issue:5

    Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Infant, Newborn; Pregnancy; Sofosbuvir

2022
Hepatitis E virus and Zoonosis: Recent Advances and Therapeutic Implications.
    Recent advances in inflammation & allergy drug discovery, 2023, Volume: 17, Issue:1

    Topics: Animals; Female; Hepatitis A; Hepatitis E; Hepatitis E virus; Humans; Pregnancy; Rats; Ribavirin; Sofosbuvir; Zoonoses

2023

Trials

3 trial(s) available for sofosbuvir and Pregnancy

ArticleYear
Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study.
    The Lancet. Microbe, 2020, Volume: 1, Issue:5

    Topics: Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C; Humans; Infant; Pregnancy; Pregnant Women; Sofosbuvir; Treatment Outcome

2020
Eliminating hepatitis C in a rural Appalachian county: protocol for the Kentucky Viral Hepatitis Treatment Study (KeY Treat), a phase IV, single-arm, open-label trial of sofosbuvir/velpatasvir for the treatment of hepatitis C.
    BMJ open, 2021, 07-05, Volume: 11, Issue:7

    Topics: Antiviral Agents; Carbamates; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Kentucky; Pregnancy; Sofosbuvir; Treatment Outcome

2021
Ledipasvir/sofosbuvir for treatment of hepatitis C virus in sofosbuvir-experienced, NS5A treatment-naïve patients: Findings from two randomized trials.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:6

    Topics: Adult; Aged; Antiviral Agents; Benzimidazoles; Coinfection; Fatigue; Female; Fluorenes; Headache; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Liver Cirrhosis; Male; Middle Aged; Pregnancy; Ribavirin; Sofosbuvir; Sustained Virologic Response; Uridine Monophosphate

2018

Other Studies

12 other study(ies) available for sofosbuvir and Pregnancy

ArticleYear
Vitrification of murine mature metaphase II oocytes perturbs DNA methylation reprogramming during preimplantation embryo development.
    Cryobiology, 2019, Volume: 87

    Topics: 5-Methylcytosine; Animals; Blastocyst; Cryopreservation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Female; Fertilization in Vitro; Metaphase; Mice; Morula; Oocytes; Oogenesis; Pregnancy; Proto-Oncogene Proteins; Vitrification

2019
Sofosbuvir-based therapy for late pregnant women and infants with severe chronic hepatitis C: A case series study.
    Journal of medical virology, 2022, Volume: 94, Issue:9

    Topics: Antiviral Agents; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Infant, Newborn; Pregnancy; Pregnant Women; Sofosbuvir; Treatment Outcome

2022
The pre-conception maternal exposure to Sofosbuvir affects the mitochondrial biogenesis in prenatal fetal tissues: Experimental study on rats.
    Molecular medicine (Cambridge, Mass.), 2023, 06-06, Volume: 29, Issue:1

    Topics: Animals; DNA, Mitochondrial; Female; Fetus; Genotype; Hepatitis C; Humans; Male; Maternal Exposure; Organelle Biogenesis; Placenta; Pregnancy; Rats; Sofosbuvir

2023
The Intergeneration Long-Lasting Consequences of Pre-Conceptional Exposure to Sofosbuvir on the Ovarian Tissues of F1 Offspring: Experimental Study on Rats.
    International journal of molecular sciences, 2023, Sep-05, Volume: 24, Issue:18

    Topics: Animals; Cell Communication; Female; Fertilization; Hepatitis C; Humans; Male; Pregnancy; Rats; Reproduction; Sofosbuvir

2023
Successful sofosbuvir lead-in monotherapy for the treatment of hepatitis C virus (HCV) infection in a pregnant woman living with HIV.
    BMJ case reports, 2019, Oct-23, Volume: 12, Issue:10

    Topics: Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Carbamates; Female; Hepatitis C; Herpes Genitalis; Heterocyclic Compounds, 4 or More Rings; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Sofosbuvir

2019
Sofosbuvir shows a protective effect against vertical transmission of Zika virus and the associated congenital syndrome in rhesus monkeys.
    Antiviral research, 2020, Volume: 182

    Topics: Animals; Antibodies, Viral; Antiviral Agents; Brazil; Female; Infectious Disease Transmission, Vertical; Macaca mulatta; Pregnancy; Pregnancy Complications, Infectious; Sofosbuvir; Translational Research, Biomedical; Viremia; Zika Virus; Zika Virus Infection

2020
Transfer of daclatasvir and sofosbuvir's main metabolite, GS-331007, across the human placenta ex vivo.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Antiviral Agents; Carbamates; Female; Hepatitis C; Humans; Imidazoles; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidines; Sofosbuvir; Uridine; Valine

2020
Responsible Inclusion of Pregnant Individuals in Eradicating HCV.
    Hepatology (Baltimore, Md.), 2021, Volume: 74, Issue:3

    Topics: Antiviral Agents; Benzimidazoles; Biomedical Research; Female; Fluorenes; Hepatitis C, Chronic; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Sofosbuvir

2021
Pregnancy outcome of anti-HCV direct-acting antivirals: Real-life data from an Egyptian cohort.
    Liver international : official journal of the International Association for the Study of the Liver, 2021, Volume: 41, Issue:7

    Topics: Antiviral Agents; Drug Therapy, Combination; Egypt; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Infant, Newborn; Pregnancy; Pregnancy Outcome; Ribavirin; Sofosbuvir; Sustained Virologic Response; Treatment Outcome

2021
Synergistic antiviral activity of Sofosbuvir and type-I interferons (α and β) against Zika virus.
    Journal of medical virology, 2018, Volume: 90, Issue:1

    Topics: Africa; Antiviral Agents; Asia; Cell Line, Tumor; Cytoprotection; Female; Fluorescent Antibody Technique; Hepatocytes; Humans; Interferon-alpha; Interferon-beta; Pregnancy; Proof of Concept Study; Sofosbuvir; Zika Virus; Zika Virus Infection

2018
Direct-Acting Antivirals to Prevent Vertical Transmission of Viral Hepatitis C: When Is the Optimal Time to Treat?
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:11

    Topics: Antiviral Agents; Drug Administration Schedule; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Ribavirin; Sofosbuvir; Time Factors

2018
Regulation of human placental drug transporters in HCV infection and their influence on direct acting antiviral medications.
    Placenta, 2018, Volume: 69

    Topics: Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Female; Guanine; Hepatitis C; Humans; Placenta; Pregnancy; Sofosbuvir; Solute Carrier Proteins; Tenofovir; Trophoblasts

2018