Page last updated: 2024-08-25

sofosbuvir and Hepatitis E

sofosbuvir has been researched along with Hepatitis E in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	11 (64.71)	24.3611
2020's	6 (35.29)	2.80

Authors

Authors	Studies
Dai, L; He, Q; Liang, Z; Lu, F; Shu, J; Wang, L; Zhang, F	1
Hon, KLE; Leung, AKC; Sridhar, S; Wong, AHC	1
Behrendt, P; Cornberg, M; Gömer, A; Hardtke, S; Horvatits, T; Jagst, M; Klöhn, M; Müller, T; Nocke, MK; Pischke, S; Schulze Zur Wiesch, J; Steinmann, E; Todt, D; Wedemeyer, H	1
Costa, J; Forns, X; García-López, M; Lens, S; Navasa, M; Pérez-Del-Pulgar, S; Sastre, L	1
Behrendt, P; Benckert, J; Cornberg, M; Hardtke, S; Koch, A; Lohse, A; Manns, MP; Müller, T; Papkalla, A; Piecha, F; Pischke, S; Steinmann, E; Todt, D; von Karpowitz, M; Wedemeyer, H	1
Akhavan, S; Calin, R; Demeret, S; Jaspard, M; Katlama, C; Mallet, V; Peytavin, G; Pourcher, V; Poynard, T; Roque-Afonso, AM; Thibault, V; Todesco, E	1
Abravanel, F; Akhavan, S; Calmus, Y; Conti, F; Guillemain, R; Lecuyer, L; Marcelin, AG; Mazzola, A; Peytavin, G; Poynard, T; Roque-Afonso, AM; Todesco, E	1
Biliotti, E; De Angelis, M; Esvan, R; Franchi, C; Garbuglia, AR; Palazzo, D; Spaziante, M; Taliani, G; Volpicelli, L	1
Drinane, M; Jing Wang, X; Watt, K	1
Kamar, N; Pan, Q	1
Drinane, M	1
Bock, CT; Eurich, D; Gerlach, UA; Hofmann, J; Maurer, MM; Mueller, T; Papp, CP; Schulz, M	1
Chtioui, H; Fraga, M; Gouttenoire, J; Marcu, C; Moradpour, D; Pascual, M; Sahli, R; Vionnet, J	1
Wahid, B	1
Dao Thi, VL; Debing, Y; Gouttenoire, J; Moradpour, D; Neyts, J; Rice, CM; Wu, X	1
Kater, AP; Schinkel, J; van der Valk, M; Zaaijer, HL	1
de Ruiter, PE; Hakim, MS; Huang, F; Nair, VP; Pan, Q; Peppelenbosch, MP; Sprengers, D; Surjit, M; Van Der Laan, LJ; Wang, W	1

Reviews

1 review(s) available for sofosbuvir and Hepatitis E

Article	Year
Hepatitis E virus and Zoonosis: Recent Advances and Therapeutic Implications. Recent advances in inflammation & allergy drug discovery, 2023, Volume: 17, Issue:1 Topics: Animals; Female; Hepatitis A; Hepatitis E; Hepatitis E virus; Humans; Pregnancy; Rats; Ribavirin; Sofosbuvir; Zoonoses	2023

Trials

1 trial(s) available for sofosbuvir and Hepatitis E

Article	Year
Sofosbuvir monotherapy fails to achieve HEV RNA elimination in patients with chronic hepatitis E - The HepNet SofE pilot study. Journal of hepatology, 2020, Volume: 73, Issue:3 Topics: Adult; Antiviral Agents; Female; Follow-Up Studies; Germany; Hepatitis E; Hepatitis E virus; Hepatitis, Chronic; Humans; Male; Middle Aged; Pilot Projects; Prospective Studies; RNA, Viral; Sofosbuvir; Treatment Failure; Young Adult	2020

Article

Year

Sofosbuvir monotherapy fails to achieve HEV RNA elimination in patients with chronic hepatitis E - The HepNet SofE pilot study.

Journal of hepatology, 2020, Volume: 73, Issue:3

Topics: Adult; Antiviral Agents; Female; Follow-Up Studies; Germany; Hepatitis E; Hepatitis E virus; Hepatitis, Chronic; Humans; Male; Middle Aged; Pilot Projects; Prospective Studies; RNA, Viral; Sofosbuvir; Treatment Failure; Young Adult

2020

Other Studies

15 other study(ies) available for sofosbuvir and Hepatitis E

Article	Year
High dose sofosbuvir and sofosbuvir-plus-ribavirin therapy inhibit Hepatitis E Virus (HEV) replication in a rabbit model for acute HEV infection. Antiviral research, 2022, Volume: 199 Topics: Animals; Antiviral Agents; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis E; Hepatitis E virus; Humans; Rabbits; Ribavirin; Sofosbuvir; Treatment Outcome	2022
Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hepatitis E patients. Hepatology (Baltimore, Md.), 2023, Dec-01, Volume: 78, Issue:6 Topics: Antiviral Agents; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis E; Humans; Sofosbuvir; Sustained Virologic Response; Treatment Outcome	2023
The challenge of chronic hepatitis E in liver transplant recipients: Failure of sofosbuvir plus ribavirin therapy. Gastroenterologia y hepatologia, 2020, Volume: 43, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Burkitt Lymphoma; Common Variable Immunodeficiency; Drug Therapy, Combination; Fatal Outcome; Focal Nodular Hyperplasia; Hepatitis E; Hepatitis E virus; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Kidney Transplantation; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Postoperative Complications; Recurrence; Ribavirin; RNA, Viral; Sofosbuvir	2020
Chronic hepatitis E in HIV/HBV coinfected patient: lack of power of sofosbuvir-ribavirin. AIDS (London, England), 2017, 06-01, Volume: 31, Issue:9 Topics: Alanine Transaminase; Antiviral Agents; Coinfection; Hepatitis B; Hepatitis E; Hepatitis E virus; Hepatitis, Chronic; HIV Infections; Humans; Male; Middle Aged; Ribavirin; Sofosbuvir; Treatment Failure; Viral Load	2017
Chronic hepatitis E in a heart transplant patient: sofosbuvir and ribavirin regimen not fully effective. Antiviral therapy, 2018, Volume: 23, Issue:5 Topics: Antiviral Agents; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; Heart Transplantation; Hepatitis E; Hepatitis E virus; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Middle Aged; Ribavirin; Sofosbuvir; Treatment Failure	2018
Autochthonous acute hepatitis E: treatment with sofosbuvir and ribavirin. Infection, 2018, Volume: 46, Issue:5 Topics: Acute-On-Chronic Liver Failure; Biomarkers; Coinfection; Drug Therapy, Combination; Fatal Outcome; Hepatitis E; Humans; Liver Function Tests; Male; Middle Aged; Ribavirin; Shock, Septic; Sofosbuvir; Treatment Outcome; Viral Load	2018
Sofosbuvir and Ribavirin Eradication of Refractory Hepatitis E in an Immunosuppressed Kidney Transplant Recipient. Hepatology (Baltimore, Md.), 2019, Volume: 69, Issue:5 Topics: Antiviral Agents; Drug Therapy, Combination; Hepatitis E; Humans; Immunosuppression Therapy; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Ribavirin; Sofosbuvir	2019
No Clear Evidence for an Effect of Sofosbuvir Against Hepatitis E Virus in Organ Transplant Patients. Hepatology (Baltimore, Md.), 2019, Volume: 69, Issue:4 Topics: Antiviral Agents; Hepatitis E; Hepatitis E virus; Humans; Kidney Transplantation; Ribavirin; Sofosbuvir	2019
Reply. Hepatology (Baltimore, Md.), 2019, Volume: 69, Issue:4 Topics: Hepatitis E; Humans; Kidney Transplantation; Ribavirin; Sofosbuvir	2019
Combination therapy of sofosbuvir and ribavirin fails to clear chronic hepatitis E infection in a multivisceral transplanted patient. Journal of hepatology, 2019, Volume: 71, Issue:1 Topics: Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis E; Hepatitis E virus; Humans; Immunosuppressive Agents; Male; Multiple Organ Failure; Organ Transplantation; Ribavirin; Sofosbuvir; Treatment Failure	2019
Sofosbuvir add-on to ribavirin for chronic hepatitis E in a cirrhotic liver transplant recipient: a case report. BMC gastroenterology, 2019, May-24, Volume: 19, Issue:1 Topics: Antiviral Agents; Chronic Disease; Drug Therapy, Combination; Hepatitis E; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Postoperative Period; Ribavirin; Sofosbuvir	2019
Successful treatment of HBV, HCV, & HEV, with 12-week long use of tenofovir, sofosbuvir, daclatasvir, and ribavirin: A case report. Journal of infection and public health, 2020, Volume: 13, Issue:1 Topics: Aged; Antiviral Agents; Asthma; Carbamates; Coinfection; Diabetes Complications; Drug Administration Schedule; Drug Therapy, Combination; Hepatitis B; Hepatitis C, Chronic; Hepatitis E; Humans; Imidazoles; Male; Pyrrolidines; Ribavirin; Sofosbuvir; Tenofovir; Treatment Outcome; Valine; Viral Load	2020
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin. Gastroenterology, 2016, Volume: 150, Issue:1 Topics: Antiviral Agents; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Hepatitis E; Hepatitis E virus; Humans; In Vitro Techniques; Ribavirin; RNA, Viral; Sofosbuvir; Virus Replication	2016
Sofosbuvir shows antiviral activity in a patient with chronic hepatitis E virus infection. Journal of hepatology, 2017, Volume: 66, Issue:1 Topics: Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis E; Hepatitis E virus; Hepatitis, Chronic; Humans; Male; Middle Aged; Ribavirin; Sofosbuvir	2017
Distinct Antiviral Potency of Sofosbuvir Against Hepatitis C and E Viruses. Gastroenterology, 2016, Volume: 151, Issue:6 Topics: Antiviral Agents; Cell Line, Tumor; DNA, Viral; Dose-Response Relationship, Drug; Genotype; HEK293 Cells; Hepacivirus; Hepatitis C, Chronic; Hepatitis E; Hepatitis E virus; Hepatocytes; Humans; RNA, Viral; Sofosbuvir; Virus Replication	2016