Page last updated: 2024-08-25

sofosbuvir and Congenital Zika Syndrome

sofosbuvir has been researched along with Congenital Zika Syndrome in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Amendoeira, FC; Bortolini, RG; Coelho, EF; da Fonseca, LB; da Silva, LSFV; da Silveira, GPE; de Araújo, JFGM; de Assis Nascimento, V; de Azevedo da Silva, AC; Dias da Silva, DM; Dos Santos, VGV; Estrela Marins, RCE; Pereira, HM; Pinto, DP; Souza, TML; Vilhena, LS1
Chahroudi, A; Kovacs-Balint, Z; Mavigner, M; Medina, A; Raper, J; Richardson, R; Rusnak, R; Sanchez, M; Schoof, N; Suthar, M; Zimmerman, MG1
Alves, AMB; Andrade, MCR; Bentes, GA; Bottino, FO; Castro, MP; Fonseca, LB; Freire, MS; Gardinali, NR; Kugelmeier, T; Lima, SMB; Linhares, JHR; Lopes, CAA; Marchevsky, RS; Melgaço, JG; Miranda, EH; Moran, J; Motta, MCVA; Nudelman, RF; Oliveira, JM; Pelajo-Machado, M; Perea, JAS; Pereira, HM; Pinto, DP; Pinto, MA; Salvador Castro Faria, SB; Sarges, K; Schmidt-Chanasit, J; Silva, ACA; Silva, MCC; Silva, SA; Soares-Bezerra, RJ; Soriano, A; Souza, TML; Trindade, GF; Vilhena, LS1
Barbosa-Lima, G; Bozza, FA; Bozza, PT; Brüning, K; Campanati, L; de Castro Faria Neto, HC; Ferreira, AC; Mattos, M; Reis, PA; Sacramento, C; Silva, PP; Souza, TML; Tanuri, A; Vieira, YR; Zaverucha-do-Valle, C1
Goebel, S; Kalkeri, R; Koide, F; Ptak, R; Snyder, B1
Beltrão-Braga, PCB; de A Zanotto, PM; Fernandes, IR; LaRock, CN; Macia, A; Mesci, P; Muotri, AR; Nizet, V; Suarez, NA; Tejwani, L1
Bullard-Feibelman, KM; Diamond, MS; Geiss, BJ; Govero, J; Salazar, V; Veselinovic, M; Zhu, Z1
Abrantes, JL; Barbosa-Lima, G; Bastos, MM; Boechat, N; Bozza, FA; Bozza, PT; Brüning, K; de Filippis, AM; de Freitas, CS; de Mello Volotão, E; de Melo, GR; Ferreira, AC; Fintelman-Rodrigues, N; Hoelz, LV; Leomil, L; Loiola, EC; Marttorelli, A; Miranda, M; Nunes, EP; Rehen, SK; Rocha, N; Sacramento, CQ; Souza, TM; Thompson, FL; Trindade, P; Tschoeke, DA; Vieira, YR1

Reviews

1 review(s) available for sofosbuvir and Congenital Zika Syndrome

ArticleYear
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020

Trials

1 trial(s) available for sofosbuvir and Congenital Zika Syndrome

ArticleYear
Development and validation of LC-MS/MS methods for the simultaneous quantification of sofosbuvir and its major metabolite (GS-331007) in blood plasma and cerebrospinal and seminal fluid: Application to a pilot clinical trial with a focus on Zika.
    Biomedical chromatography : BMC, 2023, Volume: 37, Issue:5

    Topics: Animals; Chromatography, Liquid; Humans; Limit of Detection; Plasma; Reproducibility of Results; Sofosbuvir; Tandem Mass Spectrometry; Zika Virus; Zika Virus Infection

2023

Other Studies

7 other study(ies) available for sofosbuvir and Congenital Zika Syndrome

ArticleYear
Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques.
    Journal of neuroimmunology, 2023, 08-15, Volume: 381

    Topics: Animals; Antiviral Agents; Macaca mulatta; Sofosbuvir; Zika Virus; Zika Virus Infection

2023
Sofosbuvir shows a protective effect against vertical transmission of Zika virus and the associated congenital syndrome in rhesus monkeys.
    Antiviral research, 2020, Volume: 182

    Topics: Animals; Antibodies, Viral; Antiviral Agents; Brazil; Female; Infectious Disease Transmission, Vertical; Macaca mulatta; Pregnancy; Pregnancy Complications, Infectious; Sofosbuvir; Translational Research, Biomedical; Viremia; Zika Virus; Zika Virus Infection

2020
Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae.
    Scientific reports, 2017, 08-25, Volume: 7, Issue:1

    Topics: Animals; Animals, Newborn; Antiviral Agents; Chlorocebus aethiops; Memory; Mice; Reflex, Righting; RNA, Viral; Sofosbuvir; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection

2017
Synergistic antiviral activity of Sofosbuvir and type-I interferons (α and β) against Zika virus.
    Journal of medical virology, 2018, Volume: 90, Issue:1

    Topics: Africa; Antiviral Agents; Asia; Cell Line, Tumor; Cytoprotection; Female; Fluorescent Antibody Technique; Hepatocytes; Humans; Interferon-alpha; Interferon-beta; Pregnancy; Proof of Concept Study; Sofosbuvir; Zika Virus; Zika Virus Infection

2018
Modeling neuro-immune interactions during Zika virus infection.
    Human molecular genetics, 2018, 01-01, Volume: 27, Issue:1

    Topics: Cell Line; Humans; Induced Pluripotent Stem Cells; Microglia; Models, Biological; Neural Stem Cells; Sofosbuvir; Zika Virus; Zika Virus Infection

2018
The FDA-approved drug sofosbuvir inhibits Zika virus infection.
    Antiviral research, 2017, Volume: 137

    Topics: Administration, Oral; Animals; Antiviral Agents; Cell Line; Drug Approval; Drug Evaluation, Preclinical; Humans; Mice; Sofosbuvir; United States; United States Food and Drug Administration; Zika Virus; Zika Virus Infection

2017
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.
    Scientific reports, 2017, 01-18, Volume: 7

    Topics: Antiviral Agents; Cell Line; Cell Survival; DNA-Directed RNA Polymerases; Genome, Viral; Humans; Mutation; Sofosbuvir; Viral Proteins; Virus Replication; Zika Virus; Zika Virus Infection

2017