sodium-pertechnetate-tc-99m and Sarcoma

Topics: Female; Head and Neck Neoplasms; Humans; Middle Aged; Organotechnetium Compounds; Radionuclide Imaging; Sarcoma; Sodium Pertechnetate Tc 99m; Succimer; Sulfhydryl Compounds; Technetium Tc 99m Dimercaptosuccinic Acid; Thyroid Gland

Right ventricular rupture is rare. We report its identification by radionuclide ventriculography and subsequent confirmation by contrast angiography and at operation. The aetiology in this case was a primary cardiac malignancy.

Topics: Heart Neoplasms; Heart Rupture; Heart Ventricles; Humans; Male; Middle Aged; Radionuclide Imaging; Sarcoma; Sodium Pertechnetate Tc 99m

Primary myocardial sarcomas are rare. We report the scintigraphic findings observed with TI-201, Ga-67, Tc-99m pyrophosphate, and Tc-99m pertechnetate labeled red cell gated cardiac imaging in a patient with this tumor. We found that thallium and gated blood pool imaging can be used both in the diagnosis of these tumors and the assessment of the effects of chemotherapy on the tumor and normal myocardium. The thallium study was particularly helpful in identifying the malignant nature of the tumor by showing extensive infiltration into surrounding areas.

Topics: Adult; Diphosphates; Echocardiography; Erythrocytes; Gallium Radioisotopes; Heart Neoplasms; Humans; Male; Radioisotopes; Radionuclide Imaging; Sarcoma; Sodium Pertechnetate Tc 99m; Technetium; Technetium Tc 99m Pyrophosphate; Thallium

A non-invasive method of detecting intraocular mass lesions is described which uses 67gallium citrate and 99m-technetium pertechnetate. It was used in 33 cases. In 73.7% of the patients with malignant melanoma of the eye there was a significant increase in the storage of the tracer. There was no difference in the results obtained with 67gallium citrate and 99m-technetium pertechnetate. Small, flat and peripheral tumors may not be detected. In some cases old intraocular hemorrhages may also lead to false-positive results. In contrast to the 32P-test the method described can be used in cases with opaque media. The radiation dose is about one-tenth of that given with the 32P-test.

Topics: Adolescent; Adult; Aged; Choroid Neoplasms; Diagnosis, Differential; Eye Neoplasms; Female; Gallium Radioisotopes; Humans; Iris Diseases; Male; Melanoma; Middle Aged; Nevus; Radionuclide Imaging; Sarcoma; Sodium Pertechnetate Tc 99m; Technetium; Uveal Neoplasms

Two classes of radiopharmaceuticals may be used for imaging tumors of the musculoskeletal system. The first is comprised of soft tissue or tumor specific agents such as gallium-67, bleomycin, and radionuclide-labeled antibodies, which may be useful for detecting and localizing these tumors. The other class of tracer is comprised of those with avidity for bone. The 99mTc-labeled-phosphate skeletal imaging compounds have been found to localize in a variety of soft tissue lesions, including benign and malignant tumors. In 1972, Enneking began to include bone scans in the preoperative evaluation of soft tissue masses. Later, he and his associates reported that these scans were useful in planning operative treatment of sarcomas by detecting involvement of bone by the tumors. Nearly all malignant soft tissue tumors take up bone-seeking radiopharmaceuticals, and bone involvement was indicated in two-thirds of the scans we reviewed. About half of benign soft tissue lesions had normal scans, but the other half showed uptake within the lesion and a few also showed bone involvement. Careful, thorough imaging technique is essential to proper evaluation. Multiple, high-resolution static gamma camera images in different projections are necessary to adequately demonstrate the presence or absence of soft tissue abnormality and to define the precise relationship of the tumor to the adjacent bone.

Topics: Bleomycin; Bone Neoplasms; Diphosphonates; Gallium Radioisotopes; Humans; Methods; Radionuclide Imaging; Sarcoma; Sodium Pertechnetate Tc 99m; Soft Tissue Neoplasms; Technetium; Technetium Compounds