sodium-pertechnetate-tc-99m and Renal-Artery-Obstruction

Radio-active plastic microspheres with an average diameter of 15 mu were used in eight dogs to measure renal perfusion and the results compared with time-activity curves before and after constriction of the left renal artery. It was shown that the values obtained for renal blood flow by functional scintigraphy are not accurate, particularly for moderate or low blood flow. The reason for this is primarily the distortion of the intravenously injected radio-active bolus and the consequent deviation from the so-called delta function.

Topics: Animals; Dogs; Microspheres; Radionuclide Imaging; Renal Artery; Renal Artery Obstruction; Sodium Pertechnetate Tc 99m; Technetium

Radionuclide studies were sued in three patients to evaluate renal perfusion and function within 24 hours following transluminal dilatation. In one patient, technetium-99 m pertechnetate showed good renal perfusion one and 12 hours after a post-dilatation arteriogram had shown a renal artery intimal defect. Improved clearance of iodine-131 ortho-iodohippurate from the blood demonstrated an increase in renal function 18 hours following dilatation of a stenosis at a renal allograft anastomosis in the second patient, while technetium-99 m-labeled DTPA showed an improved total glomerular filtration rate 24-hours after dilatation of a saphenous vein bypass graft in the third patient. It was concluded that renal radionuclide studies are of benefit in evaluating patients in the immediate post-dilatation period.

Topics: Adult; Aged; Angioplasty, Balloon; Evaluation Studies as Topic; Female; Glomerular Filtration Rate; Humans; Iodine Radioisotopes; Male; Middle Aged; Pentetic Acid; Radionuclide Imaging; Renal Artery Obstruction; Sodium Pertechnetate Tc 99m; Technetium; Technetium Tc 99m Pentetate