sodium-pertechnetate-tc-99m and Ovarian-Neoplasms

A case of hyperthyroid disease after total thyroidectomy is reported. An initial scintigraph with Tc-99m sodium pertechnetate confirmed the absence of uptake in the neck. The view of the pelvis revealed a rounded area of increased uptake on the left, near the sacroiliac joint (results of bone scintigraphy were negative). A wholebody scan with iodine-131 confirmed a struma ovarii that was bilateral, which occurs in 5% to 10% of patients with this condition.

Topics: Aged; Diagnosis, Differential; Female; Humans; Hyperthyroidism; Iodine Radioisotopes; Ovarian Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Struma Ovarii; Thyroidectomy

Sixty eight women, operated for ovarian carcinoma, were studied by monoclonal antibodies anti-CA-125 labeled with 131I. 99m-Tc was used for the scintigraphy. Ninety-one metastases were discovered as 73 of them were established surgically. 52/61 were confirmed in the pelvis, 19/24 in the abdominal cavity and 3/6 in the liver. Higher precision of immunoscintigraphy was found in the diagnosis of liver metastasis, when it was compared with echographic and computed tomographic examinations.

Topics: Adult; Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Carcinoma; Evaluation Studies as Topic; Female; Humans; Iodine Radioisotopes; Lymphatic Metastasis; Middle Aged; Ovarian Neoplasms; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Technetium Tc 99m Aggregated Albumin; Tomography, X-Ray Computed; Ultrasonography

A rare case of struma ovarii producing hyperthyroidism in a postmenopausal woman is reported. The ovarian tumor demonstrated uptake of both [99mTc]pertechnetate and 131I, allowing preoperative diagnosis of the condition. In females with unexplained hyperthyroidism and low 131I uptake by the cervical thyroid gland, imaging of the pelvis should be considered.

Topics: Aged; Aged, 80 and over; Female; Humans; Hypertension; Iodine Radioisotopes; Menopause; Ovarian Neoplasms; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Struma Ovarii