sodium-pertechnetate-tc-99m and Neurofibromatoses

Three soft tissue tumors were studied with 99mTc-pertechnetate scintigraphy, 67Ga-citrate scintigraphy and MRI. These tumors included schwannoma, neurofibromatosis and malignant fibrous histiocytoma. On 99mTc-pertechnetate scintigram all patients showed more increased accumulation corresponding to the tumor than on 67Ga-citrate scintigram. In conclusion, 99mTc-pertechnetate scintigraphy may be useful in detection of soft tissue tumors.

Topics: Adolescent; Citrates; Citric Acid; Evaluation Studies as Topic; Female; Histiocytoma, Benign Fibrous; Humans; Middle Aged; Neurilemmoma; Neurofibromatoses; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Soft Tissue Neoplasms

Neurofibromatosis (von Recklinghausen's disease) is a neuroectodermal disorder characterized by pigmentary changes of the skin (café-au-lait spots), cutaneous and visceral tumors (neurofibromas) and systemic abnormalities. The involvement of gastrointestinal tract in neurofibromatosis is not common. The most common symptoms, refer able to lesions in the gut, are hematemesis, melena and abdominal pain. We experienced a case of intestinal neurofibroma in von Recklinghausen's disease. The patient was a 39 year-old female who had suffered from chronic iron deficiency anemia and recurrent gastrointestinal hemorrhage due to two neurofibromas of jejunum for 3 years, which was diagnosed by superior mesenteric and ileal arteriogram and 99mTc pertechnetate-labelled RBC scan, and treated by segmental resection of jejunum with end to end anastomosis.

Topics: Adult; Anemia, Hypochromic; Chronic Disease; Female; Gastrointestinal Hemorrhage; Humans; Jejunal Neoplasms; Mesenteric Artery, Superior; Neurofibromatoses; Radiography; Radionuclide Imaging; Recurrence; Sodium Pertechnetate Tc 99m