sodium-pertechnetate-tc-99m and Lingual-Thyroid

Topics: Adult; Choristoma; Female; Humans; Lingual Thyroid; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Thyroid Gland

Lingual thyroid is a rare abnormality of thyroid development that is usually treated conservatively with levothyroxine replacement. Rarely, it becomes large enough to cause obstructive symptoms in the oral cavity, requiring definitive treatment.. This study reports on three patients with lingual thyroid treated with radioactive iodine-131 ((131)I) with successful radioablation of their ectopic thyroid tissues. Measurement of 24-hour radioactive iodine uptake within thyroidal tissues and hybrid single-photon emission computed tomography/computed tomography imaging using either iodine-123 or technetium-99m pertechnetate scans were performed in all patients demonstrating the location and size of lingual thyroid and absence of an orthotopic thyroid gland.. The aim of this study was to describe nonsurgical management of obstructive lingual thyroid tissue with (131)I therapy for lingual thyroid radioablation. Patients were prepared with a low-iodine diet and levothyroxine withdrawal prior to radioablation for optimizing (131)I uptake in ectopic thyroid tissues. Hybrid single-photon emission computed tomography/computed tomography measurement of anatomic size of lingual thyroid tissue and radioactive iodine uptake guided the selection of therapeutic doses, resulting in administration of 10.7, 17.5, and 15.4 mCi of (131)I, respectively. There were no post-therapy complications, and clinical follow-up demonstrated resolution of obstructive oropharyngeal symptoms.. Ectopic lingual thyroid tissue is rarely associated with obstructive oropharyngeal symptoms due to progressive enlargement. Radioiodine therapy with (131)I is an effective treatment modality for ablation of ectopic thyroid tissue as an alternative to surgery.

Topics: Adult; Female; Humans; Iodine Radioisotopes; Lingual Thyroid; Middle Aged; Single Photon Emission Computed Tomography Computed Tomography; Sodium Pertechnetate Tc 99m; Thyroid Dysgenesis; Thyroid Gland; Thyroid Neoplasms; Thyroxine; Treatment Outcome; Young Adult

A 51-year-old woman with a personal history of vitiligo, normal thyroid hormone studies, a simple hysterectomy for multiple uterine myomas at age 35 years, and childhood adenotonsillectomy was seen for progressive hearing loss. She reported mild asthenia, cold intolerance, mild dysphagia with frequent choking while eating and drinking, and a progressive increase in inspiratory effort, especially in the supine position. Her partner described a progressively worsening history of snoring and witnessed apneic episodes, mostly in the supine position. Mild to moderate daytime sleepiness was also present.

Topics: Antithyroid Agents; Female; Goiter, Nodular; Hearing Loss; Humans; Hyperthyroidism; Lingual Thyroid; Magnetic Resonance Imaging; Methimazole; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals; Sleep Apnea, Obstructive; Sodium Pertechnetate Tc 99m; Supine Position; Tomography, X-Ray Computed

This case study presents an incidental noting of a lingual thyroid on thyroid scintigraphy that had implications in later breast surgery. This information changed patient management and mitigated risk during intubation for breast cancer surgery.

Topics: Aged; Female; Humans; Incidental Findings; Lingual Thyroid; Sodium Pertechnetate Tc 99m; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

Dual ectopic lingual and sublingual thyroid gland is an extraordinarily rare condition. We present 1 patient with subclinical hypothyroidism. The clinical examination revealed that the thyroid gland was not palpable in its usual cervical location, whereas ultrasonography confirmed an empty thyroid bed without any ectopic thyroid tissue in the rest of the neck. The final diagnosis of dual ectopic lingual and sublingual thyroid was established by ultrasound examination through the mouth floor and confirmed by scintigraphy and CT thereafter.

Topics: Choristoma; Female; Humans; Lingual Thyroid; Middle Aged; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Thyroid Gland; Tomography, X-Ray Computed; Ultrasonography

Topics: Adolescent; Airway Obstruction; Child; Child, Preschool; Congenital Hypothyroidism; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Infant, Newborn; Lingual Thyroid; Male; Radionuclide Imaging; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Thyrotropin; Thyroxine

Topics: Contrast Media; Humans; Iodine Radioisotopes; Lingual Thyroid; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Thyroid Neoplasms; Thyroxine; Tomography, X-Ray Computed; Tongue Neoplasms