sodium-pertechnetate-tc-99m and Histiocytoma--Benign-Fibrous

Topics: Adult; Erythrocytes; False Positive Reactions; Female; Histiocytoma, Benign Fibrous; Humans; Liver; Liver Neoplasms; Sodium Pertechnetate Tc 99m; Tomography, Emission-Computed, Single-Photon

Tc-99m pertechnetate scintigraphy was compared with Tl-201 chloride and Ga-67 citrate to evaluate the avidity of Tc-99m pertechtate for malignant soft-tissue tumors. Twenty-three patients with malignant soft-tissue tumors underwent scintigraphic studies. All 23 received Tc-99m and Tl-201, whereas 14 also were injected with Ga-67. In 21 (91%) of the 23 patients, Tc-99m accumulated extensively in the tumors. Tl-201 accumulated in 12 (52%) of the 23 tumors. Ga-67 accumulated in only 5 (36%) of the 14 tumors. The avidity of Tc-99m for myxoid tumors was markedly different from the other two agents. Tc-99m accumulated in all eight myxoid tumors, while neither Tl-201 or Ga-67 showed marked accumulation except for one patient with increased accumulation of Tl-201. This study shows that Tc-99m pertechnetate has the potential to localize malignant soft-tissue tumors and may be useful in the evaluation of these tumors.

Topics: Extremities; Female; Gallium Radioisotopes; Histiocytoma, Benign Fibrous; Humans; Liposarcoma; Male; Middle Aged; Radionuclide Imaging; Retrospective Studies; Sodium Pertechnetate Tc 99m; Soft Tissue Neoplasms; Thallium Radioisotopes

The purpose of this study was to investigate the accumulation of technetium-99m pertechnetate (99mTc) in malignant soft-tissue tumors. Twenty-one patients with malignant soft-tissue tumors were subjected to 99mTc scintigraphic studies. In 19 of 21 patients (90%), 99mTc accumulated extensively in the tumors. 99mTc accumulation was especially thorough in all cases of MFH and liposarcoma. Therefore, 99mTc is useful for the local evaluation of malignant soft-tissue tumors.

Topics: Adolescent; Adult; Aged; Female; Histiocytoma, Benign Fibrous; Humans; Liposarcoma; Male; Middle Aged; Neurilemmoma; Radionuclide Imaging; Rhabdomyosarcoma; Sodium Pertechnetate Tc 99m; Soft Tissue Neoplasms

Three soft tissue tumors were studied with 99mTc-pertechnetate scintigraphy, 67Ga-citrate scintigraphy and MRI. These tumors included schwannoma, neurofibromatosis and malignant fibrous histiocytoma. On 99mTc-pertechnetate scintigram all patients showed more increased accumulation corresponding to the tumor than on 67Ga-citrate scintigram. In conclusion, 99mTc-pertechnetate scintigraphy may be useful in detection of soft tissue tumors.

Topics: Adolescent; Citrates; Citric Acid; Evaluation Studies as Topic; Female; Histiocytoma, Benign Fibrous; Humans; Middle Aged; Neurilemmoma; Neurofibromatoses; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Soft Tissue Neoplasms