sodium-pertechnetate-tc-99m and Bone-Diseases

Sixteen patients with primary fibromyalgia syndrome were assessed blindly by multiphase skeletal scintigraphy to detect possible subclinical synovitis and uptake abnormalities at tender point sites. Results were normal in 14 of the 16 patients. Mild and localized abnormalities were found in 2 patients and were possibly due to the trauma of overuse. Our multiphase skeletal scintigraphy study showed that synovitis, other evidence of arthritis, or abnormalities at tender point sites were not increased above normal expectation among our sample of patients studied with fibromyalgia.

Topics: Adolescent; Adult; Bone Diseases; Child; Connective Tissue Diseases; Female; Fibromyalgia; Humans; Male; Radionuclide Imaging; Single-Blind Method; Sodium Pertechnetate Tc 99m; Synovitis; Technetium Tc 99m Medronate

Radionuclide imaging (99mTc bone scans, 99mTc S colloid scans, 99mTc brain scans and 67gallium scans) and bone radiographs were done in 54 children with histiocytosis X. The results are discussed, compared with the literature and indications for the different nuclear medicine studies are given.

Topics: Adolescent; Bone and Bones; Bone Diseases; Child; Child, Preschool; Diphosphonates; Female; Gallium Radioisotopes; Histiocytosis, Langerhans-Cell; Humans; Infant; Liver; Male; Radiography; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Spleen; Technetium; Technetium Compounds; Technetium Tc 99m Sulfur Colloid

The nuclear medical diagnostic procedures listed in this article demonstrate the continual change in the significance of modern and recent techniques. The definition of the current status may be as short-lived as some radioisotopes. The tendencies are determined by aspects of radiological hygiene and the development of new technical procedures and the preference of in-vitro-examinations over in-vivo-diagnostic. On the other hand progress in immunology using labelled antibodies opens new possibilities in diagnosis and therapy. Although these possibilities are still somewhat visionary, they have already been translated into reality by experiment. For examination of thyroids further progress in sonography can be expected. In special problems tests using iodine isotopes with short half-lives and consequently lower radiation exposure will be used. At the moment the combination of technetium scintigram with sonography seems optimal and should if possible applied by the same hand. Scintigraphy of salivary gland and of cerebrospinal fluid have their unquestioned position. Brain scintigraphy has lost its importance but may reappear as an examination method using specially labelled agents for research of cerebral metabolism. The position of bone scintigraphy is similar. Its use is still justified when searching for skeletal changes which may not be seen in classical radiology. The knowledge of disturbance of local osseous metabolical disturbances does not give a specific information on the cause but demonstrates the site of disorder. Contrary its present ranking, important developments are to be expected from tumour scintigraphy. Isotope angiography, isotope lymphography and ventilation scintigraphy are to be employed when special questions arise, especially in fundamental research and for controls of therapeutic concepts.

Topics: Angiography; Bone Diseases; Brain Diseases; Cerebrospinal Fluid Otorrhea; Cerebrospinal Fluid Rhinorrhea; Diagnosis, Differential; Humans; Iodine Radioisotopes; Lymphoscintigraphy; Otorhinolaryngologic Diseases; Otorhinolaryngologic Neoplasms; Salivary Gland Diseases; Sodium Pertechnetate Tc 99m; Thyroid Diseases