sodium-pertechnetate-tc-99m and Aortic-Aneurysm

Platelet-related phenomena at the blood-surface interface of randomly placed knitted Dacron (n = 6) and polytetrafluoroethylene (ePTFE) (n = 6) interposition aortic grafts were studied in patients undergoing abdominal aortic aneurysmectomy. Luminal accumulation of platelets was assessed by infusing indium-111-oxine (400 microCi) labeled autologous platelets and imaging grafts at 1 week, 3 months, and 6 months after surgery. Image analysis included an indium ratio technique (comparing aortic graft radioactivity to that of an iliac artery) and a red blood cell technetium subtraction technique (excluding blood pool radioactivity from graft radioactivity, with the heart or iliac artery serving as reference regions). Plasma levels of beta-thromboglobulin and platelet factor 4 were correlated with platelet accumulations on the aortic prostheses. Differences in graft radioactivity or platelet-release products were not evident 1 week after surgery. Three months after implantation, Dacron and ePTFE conduits exhibited 87% and 47% (p less than 0.05) more radioactivity with the indium ratio technique than the iliac artery. Similarly, increased Dacron compared with ePTFE graft radioactivity was noted using technetium subtraction techniques: 71% vs 30% with a heart reference and 26% vs 11% with an iliac artery reference, respectively. Increases in graft radioactivity correlated with increases in both plasma beta-thromboglobulin and platelet factor 4 at 3 months (r = 0.6 to 0.9; p less than 0.05 to 0.001 depending on the imaging technique used). At 6 months, differences did not persist. In fact, technetium subtraction techniques suggested less Dacron conduit reactivity. It is speculated that differences in platelet accumulation and activation associated with different graft substrates may prove clinically important.

Topics: Adult; Aged; Aorta, Abdominal; Aortic Aneurysm; Blood Platelets; Blood Vessel Prosthesis; Erythrocytes; Humans; Indium Radioisotopes; Middle Aged; Platelet Aggregation; Polyethylene Terephthalates; Polytetrafluoroethylene; Prospective Studies; Radionuclide Imaging; Random Allocation; Sodium Pertechnetate Tc 99m

Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Erythrocytes; Gastrointestinal Hemorrhage; Humans; Male; Radionuclide Imaging; Sodium Pertechnetate Tc 99m

Radionuclide angiography and ultrasonic echolocation were used for the examination of 38 patients with aneurysms. Isotope angiography was fulfilled in all the 38 patients, ultrasonography was used in 20 patients. Radionuclide angiography and ultrasonography are thought to be sufficiently effective methods of diagnosis of vessel aneurysms.

Topics: Adult; Aneurysm; Aorta, Abdominal; Aortic Aneurysm; Female; Femoral Artery; Humans; Iliac Artery; Male; Middle Aged; Popliteal Artery; Preoperative Care; Sodium Pertechnetate Tc 99m; Ultrasonography

Topics: Aged; Aneurysm; Aorta, Thoracic; Aortic Aneurysm; Brachiocephalic Trunk; Erythrocytes; Humans; Male; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Technetium

Topics: Aortic Aneurysm; Aortic Dissection; Humans; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Technetium

We perform scinti-angiography regularly in suspected cases of dissecting aneurysms. In our experience, the dissection is well demonstrated by this method. In correctly selected cases, scinti-angiography is a method which is well tolerated by the patient and which carries very little risk, since the complications due to contrast media are absent.

Topics: Aortic Aneurysm; Aortic Dissection; Aortography; Arteriosclerosis; Diagnosis, Differential; Hematoma; Humans; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Technetium; Tomography, X-Ray Computed