sodium-oxybate and Hand-Dermatoses

Topics: 4-Butyrolactone; Allergens; Dermatitis, Allergic Contact; Dermatitis, Occupational; Glycosides; Hand Dermatoses; Humans; Hydrolysis; Magnoliopsida; Occupational Exposure; Sodium Oxybate

Alstroemerias are one of the most common plants that cause allergic contact dermatitis in floral workers. This colorful plant has gained great popularity among florists and their patrons. This concise review will help dermatologists to gain familiarity with this plant and show how to diagnose problems that it may cause.

Topics: 4-Butyrolactone; Adult; Allergens; Dermatitis, Allergic Contact; Glucosides; Glycosides; Hand Dermatoses; Humans; Male; Occupational Diseases; Occupational Exposure; Patch Tests; Plant Extracts; Plants; Sodium Oxybate

Astroemeria is an increasingly common cause of allergic contact dermatitis. We report a case of occupational contact dermatitis that was transferred with job duties. When advising patients about their risk, it is advisable to discuss the risk to others in the setting as well.

Topics: Allergens; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Glycosides; Hand Dermatoses; Humans; Male; Middle Aged; Plants; Sodium Oxybate

Betaxolol ophthalmic solution has been associated with periocular skin hyperpigmentation. We report a case of a woman with hyperpigmentation of the fingers associated with oral betaxolol. Based on case reports associated with the topical ophthalmic product, we believe the hyperpigmentation was likely caused by oral betaxolol.

Topics: Administration, Oral; Allergens; Antihypertensive Agents; Betaxolol; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Fingers; Glycosides; Hand Dermatoses; Humans; Hyperpigmentation; Middle Aged; Plants; Sodium Oxybate

Concern about the increasing incidence of hand dermatitis in floral shop workers in the United States and its possible association to the plant Alstroemeria, a flower that has become popular since its introduction in 1981, prompted investigation of the prevalence and cause of hand dermatitis in a sample of floral workers. Fifty-seven floral workers were surveyed, and 15 (26%) reported hand dermatitis within the previous 12 months. Sixteen floral workers (eight with dermatitis) volunteered to be patch tested to the North American Contact Dermatitis Group Standard and Perfume Trays, a series of eight pesticides and 20 plant allergens. Of four of seven floral designers and arrangers who reported hand dermatitis, three reacted positively to patch tests to tuliposide A, the allergen in Alstroemeria. Patch test readings for all other plant extracts were negative. A positive reading for a test to one pesticide, difolatan (Captafol), was noted, the relevance of which is unknown.

Topics: Adolescent; Adult; Allergens; Dermatitis, Contact; Dermatitis, Occupational; Female; Glycosides; Hand Dermatoses; Humans; Male; Patch Tests; Pennsylvania; Plants; Prevalence; Sodium Oxybate

Tulip fingers, an allergic contact dermatitis from handling tulip bulbs, is a common occupational problem among workers in the European tulip industry. We describe five of nine workers who sort and package flower bulbs at a central Pennsylvania bulb distribution center; all five had tulip fingers confirmed by positive patch tests to pieces of tulip bulbs and to tuliposide A, the allergen in tulips. The diagnosis of tulip fingers should be considered in any patient with a hand dermatitis who works in the flower industry, especially those who frequently handle bulbs.

Topics: 4-Butyrolactone; Adult; Aged; Dermatitis, Contact; Dermatitis, Occupational; Female; Fingers; Glycosides; Hand Dermatoses; Humans; Male; Middle Aged; Patch Tests; Plants; Sodium Oxybate

Two female florists developed dermatitis of the fingertips. Patch testing revealed allergic contact dermatitis to the flower, Alstroemeria, used in floral arrangements. They had positive patch tests to portions of Alstroemeria, and to tuliposide A, the allergen in this plant. Vinyl gloves were not helpful since tuliposide A readily penetrates through these gloves. Nitrile gloves may be protective since they prevented positive patch test to tuliposide A.

Topics: Adult; Allergens; Dermatitis, Contact; Dermatitis, Occupational; Female; Glycosides; Hand Dermatoses; Humans; Patch Tests; Plants; Protective Clothing; Sodium Oxybate