sodium-nitrite and Lymphoma--Non-Hodgkin

sodium-nitrite has been researched along with Lymphoma--Non-Hodgkin* in 1 studies

Other Studies

1 other study(ies) available for sodium-nitrite and Lymphoma--Non-Hodgkin

Article	Year
Carcinogenic effect of a quanidine pesticide administered with sodium nitrite on adult mice and on the offspring after prenatal exposure. Cancer letters, 1978, Volume: 5, Issue:2 Adult Swiss mice were treated intragastrically during the last week of pregnancy with the fungicide dodecylquanidine acetate (dodine, DGA) together with 0.05% sodium nitrite. The incidence of malignant lymphomas, lung adenomas and hepatomas was 30--70% in females. The first tumors appeared 4 months after delivery in the FO generation and at 6--7 months in the F1 generation. Among the untreated control mice the frequency of spontaneous tumors was 6%, and lymphomas developed, if at all, only after 10 months. The oncogenic activity of DGA with sodium nitrite in the offspring was dependent on the dose of DGA.A and C type RNA virus particles were demonstrated in lymphomas by electronmicroscopy. DGA alone had no effect on the cancer incidence. Topics: Animals; Carcinogens; Drug Synergism; Female; Fungicides, Industrial; Guanidines; Inclusion Bodies, Viral; Lymphoma, Non-Hodgkin; Male; Maternal-Fetal Exchange; Mice; Nitrites; Pregnancy; Sarcoma, Experimental; Sex Factors; Sodium Nitrite	1978

Article

Year

Carcinogenic effect of a quanidine pesticide administered with sodium nitrite on adult mice and on the offspring after prenatal exposure.

Cancer letters, 1978, Volume: 5, Issue:2

Adult Swiss mice were treated intragastrically during the last week of pregnancy with the fungicide dodecylquanidine acetate (dodine, DGA) together with 0.05% sodium nitrite. The incidence of malignant lymphomas, lung adenomas and hepatomas was 30--70% in females. The first tumors appeared 4 months after delivery in the FO generation and at 6--7 months in the F1 generation. Among the untreated control mice the frequency of spontaneous tumors was 6%, and lymphomas developed, if at all, only after 10 months. The oncogenic activity of DGA with sodium nitrite in the offspring was dependent on the dose of DGA.A and C type RNA virus particles were demonstrated in lymphomas by electronmicroscopy. DGA alone had no effect on the cancer incidence.

Topics: Animals; Carcinogens; Drug Synergism; Female; Fungicides, Industrial; Guanidines; Inclusion Bodies, Viral; Lymphoma, Non-Hodgkin; Male; Maternal-Fetal Exchange; Mice; Nitrites; Pregnancy; Sarcoma, Experimental; Sex Factors; Sodium Nitrite

1978