sodium-iodate and Uveitis

sodium-iodate has been researched along with Uveitis* in 2 studies

Other Studies

2 other study(ies) available for sodium-iodate and Uveitis

Article	Year
[Participation of sodium iodate in the induction of experimental autoimmune uveoretinitis (EAU)]. Nippon Ganka Gakkai zasshi, 1991, Volume: 95, Issue:11 It is known that Brown Norway (BN) rats show resistance to the development of experimental autoimmune uveoretinitis (EAU). Although BN rats don't develop EAU easily when they were immunized with S antigen containing emulsified complete Freund's adjuvant, this paper reports on the development of EAU at the rate of 40-60% in BN rats when immunization is preceded by an injection of more than 0.5 mg (1.79 mg/kg of body wt) of sodium iodate which leads to the destruction of retinal pigment epithelium (RPE). It was thought that the destruction of RPE participated in the induction of EAU. Therefore, it is considered that the existence of RPE may play an important role in the induction of EAU. Topics: Animals; Antigens; Arrestin; Autoimmune Diseases; Eye Proteins; Immunity, Cellular; Iodates; Male; Pigment Epithelium of Eye; Rats; Rats, Inbred BN; Retinitis; Uveitis	1991
The hyperosmolarity-induced response of the ocular standing potential in mature rabbits. Documenta ophthalmologica. Advances in ophthalmology, 1987, Volume: 66, Issue:4 The hyperosmolarity-induced response of the ocular standing potential (SP) provides a method of testing the function of the retinal pigment epithelium (RPE) without using light stimulation. In this study, the changes in potential level occurring after a short-term intravenous injection of 10 ml of 20% mannitol were determined by means of a direct current amplifier for the following groups: Group 1, normal rabbit eyes; Group 2, rabbit eyes in which the RPE was damaged by sodium iodate; Group 3, rabbit eyes in which the photoreceptors were damaged by monoiodoacetic acid; Group 4, rabbit eyes with uveoretinitis experimentally induced by Arthus-type inflammation. The following results were obtained: 1. The hyperosmolarity-induced SP response consisted of a transient increase in potential level (positive wave) in Group 1. 2. For Group 2 a transient decrease in potential level (negative wave) was obtained, i.e., a reversal of the normal positive response to negative wave. 3. A positive wave and no reversal was found for Group 3. 4. For Group 4 a negative wave and a reversal of the normal response was obtained. These hyperosmolarity-induced SP responses provide additional information concerning the possibilities of the method for studying the function of the RPE. Topics: Aging; Animals; Arthus Reaction; Electrophysiology; Electroretinography; Iodates; Iodoacetates; Iodoacetic Acid; Mannitol; Ocular Physiological Phenomena; Osmolar Concentration; Rabbits; Retinitis; Uveitis	1987

Article

Year

[Participation of sodium iodate in the induction of experimental autoimmune uveoretinitis (EAU)].

Nippon Ganka Gakkai zasshi, 1991, Volume: 95, Issue:11

It is known that Brown Norway (BN) rats show resistance to the development of experimental autoimmune uveoretinitis (EAU). Although BN rats don't develop EAU easily when they were immunized with S antigen containing emulsified complete Freund's adjuvant, this paper reports on the development of EAU at the rate of 40-60% in BN rats when immunization is preceded by an injection of more than 0.5 mg (1.79 mg/kg of body wt) of sodium iodate which leads to the destruction of retinal pigment epithelium (RPE). It was thought that the destruction of RPE participated in the induction of EAU. Therefore, it is considered that the existence of RPE may play an important role in the induction of EAU.

Topics: Animals; Antigens; Arrestin; Autoimmune Diseases; Eye Proteins; Immunity, Cellular; Iodates; Male; Pigment Epithelium of Eye; Rats; Rats, Inbred BN; Retinitis; Uveitis

1991

The hyperosmolarity-induced response of the ocular standing potential in mature rabbits.

Documenta ophthalmologica. Advances in ophthalmology, 1987, Volume: 66, Issue:4

The hyperosmolarity-induced response of the ocular standing potential (SP) provides a method of testing the function of the retinal pigment epithelium (RPE) without using light stimulation. In this study, the changes in potential level occurring after a short-term intravenous injection of 10 ml of 20% mannitol were determined by means of a direct current amplifier for the following groups: Group 1, normal rabbit eyes; Group 2, rabbit eyes in which the RPE was damaged by sodium iodate; Group 3, rabbit eyes in which the photoreceptors were damaged by monoiodoacetic acid; Group 4, rabbit eyes with uveoretinitis experimentally induced by Arthus-type inflammation. The following results were obtained: 1. The hyperosmolarity-induced SP response consisted of a transient increase in potential level (positive wave) in Group 1. 2. For Group 2 a transient decrease in potential level (negative wave) was obtained, i.e., a reversal of the normal positive response to negative wave. 3. A positive wave and no reversal was found for Group 3. 4. For Group 4 a negative wave and a reversal of the normal response was obtained. These hyperosmolarity-induced SP responses provide additional information concerning the possibilities of the method for studying the function of the RPE.

Topics: Aging; Animals; Arthus Reaction; Electrophysiology; Electroretinography; Iodates; Iodoacetates; Iodoacetic Acid; Mannitol; Ocular Physiological Phenomena; Osmolar Concentration; Rabbits; Retinitis; Uveitis

1987