sodium-iodate and Retinal-Neovascularization

sodium-iodate has been researched along with Retinal-Neovascularization* in 1 studies

Other Studies

1 other study(ies) available for sodium-iodate and Retinal-Neovascularization

Article	Year
Effects of sodium iodate on experimental subretinal neovascularization in the primate. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1990, Volume: 200, Issue:1 We investigated the role of the retinal pigment epithelium (RPE) in the development of subretinal neovascularization (SRN) induced by bilateral laser photocoagulation of the retinas in monkeys. RPE function was affected by a unilateral carotid injection of sodium iodate, a selective RPE toxin, before laser photocoagulation. This caused severe RPE damage in the ipsilateral eye, but did not affect the contralateral eye. After laser photocoagulation no SRN was demonstrable clinically or histopathologically in the ipsilateral eye; in contrast, active SRN showing extensive fluorescein leakage was found in the contralateral eye. These results suggest that RPE may play a role in the development of laser-induced SRN. Topics: Animals; Fluorescein Angiography; Fundus Oculi; Iodates; Light Coagulation; Macaca fascicularis; Macrophages; Pigment Epithelium of Eye; Retinal Neovascularization	1990

Article

Year

Effects of sodium iodate on experimental subretinal neovascularization in the primate.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1990, Volume: 200, Issue:1

We investigated the role of the retinal pigment epithelium (RPE) in the development of subretinal neovascularization (SRN) induced by bilateral laser photocoagulation of the retinas in monkeys. RPE function was affected by a unilateral carotid injection of sodium iodate, a selective RPE toxin, before laser photocoagulation. This caused severe RPE damage in the ipsilateral eye, but did not affect the contralateral eye. After laser photocoagulation no SRN was demonstrable clinically or histopathologically in the ipsilateral eye; in contrast, active SRN showing extensive fluorescein leakage was found in the contralateral eye. These results suggest that RPE may play a role in the development of laser-induced SRN.

Topics: Animals; Fluorescein Angiography; Fundus Oculi; Iodates; Light Coagulation; Macaca fascicularis; Macrophages; Pigment Epithelium of Eye; Retinal Neovascularization

1990