sodium-hypochlorite and Thrombosis

108 patients with atherosclerosis of aorto-iliac segment have undergone various reconstructive operations on this segment. Depending on the treatment all the patients were divided in 2 groups (test group--54 patients, control group--54 patients). The patients of the control group received aspirin, rheopolyglucin and trental for correction of hemorheology and hemocoagulation disorders. In patients of the test group at the same time as this treatment, the indirect electrochemical blood oxidation by intravenous infusion of 0.03% sodium hypochlorite was applied. Regional hemodynamics, hemorheology and hemostasis indices were studied in all the patients. It was established that indirect electrochemical blood oxidation permits to significantly improve the hemorheology indices, to diminish thrombophilia phenomenon during the treatment and early postoperative period. It was noted that early thrombotic reocclusion and amputations rates were reduced in the test group.

Topics: Adult; Aged; Anticoagulants; Aorta, Abdominal; Aortic Diseases; Arterial Occlusive Diseases; Aspirin; Dextrans; Electrochemistry; Hemodynamics; Hemorheology; Humans; Iliac Artery; Infusions, Intravenous; Injections, Intravenous; Middle Aged; Oxidants; Oxidation-Reduction; Pentoxifylline; Platelet Aggregation Inhibitors; Postoperative Complications; Sodium Hypochlorite; Thrombosis