sodium-hypochlorite and Postoperative-Complications

The main objective of the present study is to evaluate the effects and possible benefits with regard to the postoperative period of lower third molar extractions, comparing the intraalveolar application of a bioadhesive gel of 0.2% chlorhexidine (CHX) to the use of a mouthwash with a super-oxidized solution, (SOS) Dermacyn® Wound Care (Oculus Innovative Sciences lnc., California, USA).. A randomized double-blind study was carried out in 20 patients with a split-mouth design, with a total of 40 extractions of symmetrically impacted bilateral lower third molars. Patients were divided into two groups, a control group (C = 20) and an experimental group (D = 20). Any infectious complications, wound healing, plaque accumulation in the stitches, and presence of trismus and inflammation were evaluated using the distance between different facial points, at three, eight, and fifteen days after extraction. Pain, swelling, and amount of analgesics taken were evaluated using the VAS scale throughout the 15 days following extraction. Tolerance to treatment was evaluated using a verbal scale. Results were statistically compared using the Student's t- and chi-squared tests.. No statistically significant differences were found between the two groups with regard to infectious complications, swelling, or wound healing. Use of analgesics and self-reported pain levels were slightly lower in the experimental group than in the control group during days 6 and 7 of the study (p < 0.05). The global treatment tolerance was satisfactory and similar in both groups.. Both CHX and SOS are effective at improving the postoperative period after extraction of lower third molars.

Topics: Adult; Chlorhexidine; Double-Blind Method; Drug Combinations; Edema; Female; Gels; Humans; Hypochlorous Acid; Male; Mandible; Molar, Third; Mouthwashes; Pain, Postoperative; Postoperative Complications; Prospective Studies; Sodium Hypochlorite; Tooth Extraction; Wound Healing

The aim of this monocentric, randomized, comparative, open study was to evaluate the safety of Amukine 0.06% solution (an isotonic hypochloride sodium solution) versus a 5% povidone iodine solution (Bétadine 5% solution for ocular irrigation) in antisepsis before cataract surgery.. One hundred and thirteen patients, aged between 49 and 90 years, were included and split, after randomization, into two groups: one testing Amukine 0.06%, the other testing a 5% povidone iodine solution. For each group, after local anesthesia, the antiseptic procedure consisted of an antisepsis of periocular teguments followed by an eye antisepsis through the instillation of two drops of the tested product in the conjunctival fornices. The safety evaluation was performed by grading superficial punctate keratitis 24 hours after surgery (slit lamp examination after fluorescein instillation). Conjunctival hyperemia scores by examination of the bulbar conjunctiva before the first instillation, immediately before surgery, and 24 hours after surgery were also compared.. One hundred and seven reports were analyzed. Concerning the presence of corneal superficial punctate keratitis 24 hours after surgery, mean scores were not different (0.27 for the Amukine 0.06% group and 0.38 for the povidone iodine group; p=0.27 Mann Whitney test). The observations did not show a different progression of conjunctival hyperemia depending on the treatment group (p=0.65 (immediately after application) and p=0.52 (after 24 hours); Mann Whitney test).. In this study, the ocular safety of Amukine 0.06% solution was not different from a 5% povidone iodine solution. Therefore, Amukine 0.06% is a new interesting approach to surgical antisepsis in ophthalmology and an alternative in case of iodine allergy.

Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Local; Antisepsis; Cataract Extraction; Conjunctiva; Disinfectants; Eye; Female; Humans; Hyperemia; Iodophors; Keratitis; Male; Middle Aged; Postoperative Complications; Povidone-Iodine; Preoperative Care; Safety; Sodium Hypochlorite; Time Factors

The article presents an analysis of surgical treatment of 2155 patients with incarcerated hernias of the anterior abdominal wall. Pyo-septic complications took place in 24.3%. A comparison of results of treatment by traditional methods with those using solution of sodium hypochlorite (indirect electrochemical oxidation of blood) has shown that in the group of patient treated with sodium hypochlorite lethality was reduced from (18.8 +/- 0.2)% to (11.2 +/- 0.2)%, the amount of suppuration of the operative wound was 1.8 times less and the average number of bed-days was (4.5 +/- 0.2) less.

Topics: Disinfectants; Female; Hernia; Herniorrhaphy; Humans; Infant, Newborn; Infusions, Intravenous; Male; Peritonitis; Postoperative Care; Postoperative Complications; Recurrence; Sepsis; Sodium Hypochlorite; Solutions; Time Factors

Topics: Aged; Enterobacter cloacae; Enterobacteriaceae Infections; Humans; Hypochlorous Acid; Male; Pacemaker, Artificial; Postoperative Complications; Prosthesis-Related Infections; Sodium Hypochlorite; Treatment Outcome

Topics: Aged, 80 and over; Humans; Hypochlorous Acid; Male; Postoperative Complications; Scalp; Sodium Hypochlorite; Surgical Wound; Treatment Outcome; Wound Healing

An analysis of complex examination and results of treatment was made in 290 patients with diffuse peritonitis. The patients were divided into two groups according to way of sanation of the abdominal cavity. The sanation with 0.03% aqueous solution of sodium hypochlorite was used for the first group of 155 patients. The immobilized forms of sodium hypochlorite in carboxymethyl cellulose gel were applied in the second group. The rate of postoperative complications was decreased on 15.4%, the lethality--on 8.2% in the case of application of the immobilized forms of sodium hypochlorite. The developed technology allowed increasing of physical component of life quality of the patients in 1.3 times, though it didn't influence on psychical component.

Topics: Abdominal Cavity; Carboxymethylcellulose Sodium; Comparative Effectiveness Research; Disinfectants; Drainage; Drug Carriers; Female; Gels; Humans; Male; Middle Aged; Peritoneal Lavage; Peritonitis; Postoperative Complications; Quality of Life; Severity of Illness Index; Sodium Hypochlorite; Survival Analysis; Tissue Adhesions; Treatment Outcome

The 1st group consisted of 68 patients with the diffuse peritonitis, who were treated with the use of traditional approach, i.e., laparotomy, elimination of the peritonitis source, nasointestinal intubation, abdominal cavity sanation and drainage. Within 24--48 hours all these patients had videoendoscopic abdominal sanation with the injection of 200 ml 0.03% water solution of sodium hypochlorite. The 2nd group, consisted of 41 patients. The first treatment stage was the same, but during the videoendoscopic stage the pulsing stream of the antiseptic was used and the procedure ended with intraabdominal injection of 200 ml 0.03% water solution of sodium hypochlorite immobilized in gel. All patients of the 2nd group showed better recovery results.

Topics: Abdominal Cavity; Adult; Aged; Anti-Infective Agents, Local; Drainage; Female; Humans; Laparotomy; Male; Middle Aged; Peritoneal Lavage; Peritonitis; Postoperative Complications; Retrospective Studies; Sodium Hypochlorite; Suppuration; Tissue Adhesions; Treatment Outcome; Video-Assisted Surgery

Complex examination and the following treatment of 380 patients with diffuse purulent peritonitis were analyzed. The patients were divided into 2 groups. The first group included 245 patients to whom the sanitization of the abdominal cavity used traditional antiseptics. The main group included 135 patients to whom the immobilized form of sodium hypochlorite in the carboxymethyl cellulose was introduced instead of aqueous solution. An original method of sanitization of the abdominal cavity allows 1.2-1.5 times decreased degree of endotoxicosis, 2-2.5 times improved the motor-evacuatory function of the intestine in different forms of treatment of peritonitis. In the main group of patients the number of postoperative complications was 10% less, lethality was 8.2% less.

Topics: Abdominal Cavity; Anti-Infective Agents, Local; APACHE; Carboxymethylcellulose Sodium; Combined Modality Therapy; Drug Carriers; Drug Delivery Systems; Female; Gastrointestinal Motility; Humans; Male; Peritonitis; Postoperative Complications; Sodium Hypochlorite; Suppuration; Surgical Procedures, Operative; Treatment Outcome

The objective of this prospective clinical study was to evaluate the incidence of flare-ups (pain and/or swelling requiring endodontic interappointment and emergency treatment) and identify the risk factors associated with their occurrence in patients who received endodontic treatment from June 2006 to June 2007 at the endodontics clinic of the São Paulo Dental Association (APCD), Jardim Paulista branch, São Paulo, Brazil. The incidence of flare-ups was 1.71% out of 408 teeth that had received endodontic therapy. Statistical analysis using the chi-squared test (P < .05) indicated a direct correlation between the flare-up rate and the presence of a periradicular radiolucency.

Topics: Adult; Brazil; Edema; Edetic Acid; Emergency Treatment; Female; Humans; Incidence; Male; Middle Aged; Pain, Postoperative; Periapical Diseases; Postoperative Complications; Prospective Studies; Retreatment; Risk Factors; Root Canal Irrigants; Root Canal Preparation; Root Canal Therapy; Sodium Hypochlorite; Toothache; Young Adult

108 patients with atherosclerosis of aorto-iliac segment have undergone various reconstructive operations on this segment. Depending on the treatment all the patients were divided in 2 groups (test group--54 patients, control group--54 patients). The patients of the control group received aspirin, rheopolyglucin and trental for correction of hemorheology and hemocoagulation disorders. In patients of the test group at the same time as this treatment, the indirect electrochemical blood oxidation by intravenous infusion of 0.03% sodium hypochlorite was applied. Regional hemodynamics, hemorheology and hemostasis indices were studied in all the patients. It was established that indirect electrochemical blood oxidation permits to significantly improve the hemorheology indices, to diminish thrombophilia phenomenon during the treatment and early postoperative period. It was noted that early thrombotic reocclusion and amputations rates were reduced in the test group.

Topics: Adult; Aged; Anticoagulants; Aorta, Abdominal; Aortic Diseases; Arterial Occlusive Diseases; Aspirin; Dextrans; Electrochemistry; Hemodynamics; Hemorheology; Humans; Iliac Artery; Infusions, Intravenous; Injections, Intravenous; Middle Aged; Oxidants; Oxidation-Reduction; Pentoxifylline; Platelet Aggregation Inhibitors; Postoperative Complications; Sodium Hypochlorite; Thrombosis

In this paper we describe the use of circular myotomies to approximate the oesophageal ends resulting from resection of an oesophageal stricture due to ingestion of domestic bleach. This procedure has spared the child from major oesophageal surgery with its known morbidity. This is the second case described using this method from this institute.

Topics: Barium Sulfate; Burns, Chemical; Child, Preschool; Esophageal Stenosis; Esophagoplasty; Female; Follow-Up Studies; Humans; Postoperative Complications; Radiography; Sodium Hypochlorite

Data from 45 adult patients with flame burns covering up to 20 per cent EAB (Group 1), 21-40 per cent (Group 2), and 41-60 per cent (Group 3) are presented. Each group contains 15 patients with 29 females and 16 males, and females had the more extensive burns. All the patients were treated by the exposure method followed by Eusol dressings beginning between post burn days 5 and 7, i.e. as soon as infection was detected or the eschar had started separating. Eusol is an effective antibacterial agent and also assists in slough separation. It appears to be inactive against living tissues and helps obtain healthy granulation tissue. The bed thus created is ideal for grafting. A burn wound up to 40 per cent EAB is suitable for treatment by the exposure-Eusol method. Septicaemia was the common cause of mortality and its incidence was directly related to the extent of injury.

Topics: Adolescent; Adult; Anti-Infective Agents; Borates; Burns; Female; Humans; Male; Postoperative Complications; Skin Transplantation; Sodium Hypochlorite

Glutaraldehyde-treated human amniotic membranes were used to repair rabbit bladders after supratrigonal cystectomies. The membranes maintained the integrity of the bladders until healing and reepithelialization occurred. There was no significant loss of bladder capacity or decreased renal function postoperatively. Calcification did not occur on the membranes but was noted on chromic sutures retaining the membranes in 7 of 27 bladders. These findings suggest that glutaraldehyde-stabilized amnion is well tolerated by the urothelium and may serve as a suitable material for replacement of genitourinary tissues.

Topics: Amnion; Animals; Biological Dressings; Bioprosthesis; Female; Postoperative Complications; Rabbits; Sodium Hypochlorite; Urinary Bladder; Urinary Bladder Calculi