sodium-hypochlorite has been researched along with Pneumonia* in 3 studies
3 other study(ies) available for sodium-hypochlorite and Pneumonia
| Article | Year |
|---|---|
Exposure to Sodium Hypochlorite or Cigarette Smoke Induces Lung Injury and Mechanical Impairment in Wistar Rats.
Pulmonary irritants, such as cigarette smoke (CS) and sodium hypochlorite (NaClO), are associated to pulmonary diseases in cleaning workers. We examined whether their association affects lung mechanics and inflammation in Wistar rats. Exposure to these irritants alone induced alterations in the lung mechanics, inflammation, and remodeling. The CS increased airway cell infiltration, acid mucus production, MMP-12 expression, and alveolar enlargement. NaClO increased the number of eosinophils and macrophages in the bronchoalveolar lavage fluid, with cells expressing IL-13, MMP-12, MMP-9, TIMP-1, and iNOS in addition to increased IL-1β and TNF-α levels. Co-exposure to both irritants increased epithelial and smooth muscle cell area, acid mucus production, and IL-13 expression in the airways, while it reduced the lung inflammation. In conclusion, the co-exposure of CS with NaClO reduced the pulmonary inflammation, but increased the acidity of mucus, which may protect lungs from more injury. A cross-resistance in people exposed to multiple lung irritants should also be considered. Topics: Animals; Bronchoalveolar Lavage Fluid; Cigarette Smoking; Humans; Inflammation; Interleukin-13; Irritants; Lung; Lung Injury; Matrix Metalloproteinase 12; Nicotiana; Pneumonia; Rats; Rats, Wistar; Sodium Hypochlorite | 2022 |
Severe lung injury after exposure to chloramine gas from household cleaners.
Topics: Airway Obstruction; Ammonia; Chloramines; Female; Household Products; Humans; Middle Aged; Pneumonia; Sodium Hypochlorite; Tracheostomy | 1999 |
Toxic pneumonitis from mixing household cleaners.
In the past year we have seen three cases of life-threatening toxic pneumonitis caused by exposure to mixtures of household ammonia and bleach. This particular mixture forms intermediary chloramine compounds that cause toxic pneumonitis. Each patient had a prolonged hospitalization and was left with symptomatic residual roentgenographic changes. Exposure to mixtures of household ammonia and bleach may be a frequent cause of acute pneumonitis that is not well recognized. Topics: Aged; Ammonia; Female; Household Products; Humans; Middle Aged; Pneumonia; Sodium Hypochlorite | 1986 |