sodium-hypochlorite and Intestinal-Obstruction

Presented are the results of experimental research on 144 animals (the rats Wistar), on whom was carried out resection of a part of large intestine and a intestinal anastamosis was formed in the presents of acute intestinal obstruction and peritonitis. The sanitation of abdominal cavity in the basic group of animals (74) was performed using sodium hypochlorite solution and dissolved ozone. The intestinal lavage was carried out by dissolved ozone with the subsequent introduction of ozonized oil Ozonide in the area of intestinal anastamosis. The combined application of ozone and sodium produces an expressed samative effect which leads to healing of intestinal anastamosis and decreases unstability of intestinal sutures and mortality.

Topics: Abdominal Cavity; Acute Disease; Animals; Disease Models, Animal; Intestinal Obstruction; Oxidants, Photochemical; Ozone; Peritonitis; Rats; Rats, Wistar; Remission Induction; Sodium Hypochlorite

Strangulation colorectal obstruction was modeled in 60 Wistar rats. Necrotic segment of the intestine was resected under conditions of peritonitis and end-to-end intestinal anastomosis was performed on a PCV catheter conducted through the anus. Sodium hypochlorite and ozone solution were used for sanitation of the abdominal cavity and intestinal lavage, and the intestinal anastomosis was coated with Ozonide (ozonized oil). The use of physicochemical methods notably reduced the incidence of postoperative pyoinflammatory complications, incompetence of intestinal anastomosis sutures, and animal mortality.

Topics: Anastomosis, Surgical; Animals; Colonic Diseases; Combined Modality Therapy; Ileus; Intestinal Obstruction; Intestines; Ozone; Rats; Rectal Diseases; Sodium Hypochlorite; Wound Healing