sodium-hypochlorite and Gingival-Diseases

This study aimed to evaluate the clinical effects of 0.05% sodium hypochlorite mouth rinse on supragingival biofilm and gingival inflammation.. The study was performed as a controlled, randomised, investigator-blinded, parallel group trial in 40 prison inmates. Following a preparatory period to obtain a plaque- and gingivitis-free dentition, tooth-brushing was substituted for 21 days by supervised twice daily rinsing with either 15 ml of fresh solution 0.05% sodium hypochlorite or 15 ml of distilled water. Clinical outcomes were assessed using the Quigley-Hein Plaque Index (QHPI), the Löe and Silness Gingival Index (L&SGI) and bleeding on probing. Adverse events were evaluated by questionnaire, visual examination and clinical photographs..   At day 21, the average QHPI score had increased to 3.82 in the water rinse group and 1.98 in the sodium hypochlorite rinse group. The average L&SGI score had increased to 2.1 in the water rinse group and 1.0 in the sodium hypochlorite rinse group, and the average percentage of sites that bled on probing had increased to 93.1% in the water rinse group and 56.7% in the sodium hypochlorite rinse group. Differences were statistically significant (P = 0.001). A brown extrinsic tooth stain along the gingival margin appeared in 100% of participants in the sodium hypochlorite rinse group and in 35.0% of participants in the water rinse group (P < 0.05)..   An oral rinse with 0.05% sodium hypochlorite resulted in significant reductions in supragingival biofilm accumulation and gingival inflammation. Dilute sodium hypochlorite may represent an efficacious, safe and affordable antimicrobial agent in the prevention and treatment of periodontal disease.

Topics: Adult; Anti-Infective Agents; Biofilms; Dental Plaque; Dental Plaque Index; Gingival Diseases; Humans; Male; Mouthwashes; Periodontal Index; Prisoners; Single-Blind Method; Sodium Hypochlorite; Treatment Outcome

To report clinical complications (pain, necrotic gingival tissue and bone sequestration) resulting from accidental injection of sodium hypochlorite.. Root canal treatment is a routine clinical procedure with few reported complications. Sodium hypochlorite (NaOCl) is commonly used as an irrigant during the procedure because of its tissue-dissolving, antibacterial and lubricating properties. This paper presents a case in which accidental injection of sodium hypochlorite into the lingual gingiva of a female patient caused gingival and bone necrosis. Surgical intervention was required.. *Sodium hypochlorite is dangerous if injected into the tissues. *The presentation of sodium hypochlorite in glass, anaesthetic type cartridges is potentially dangerous, and should be condemned. *All healthcare workers should check carefully the contents of any syringe before injecting into patients.

Topics: Adult; Anesthesia, Dental; Female; Gingival Diseases; Humans; Medication Errors; Osteonecrosis; Pulpitis; Root Canal Irrigants; Sodium Hypochlorite

Topics: Adult; Dental Cementum; Gingiva; Gingival Diseases; Gingival Recession; Humans; Middle Aged; Sodium Hypochlorite; Subgingival Curettage; Surgical Flaps; Tooth Root

The effect of some agents on the antimicrobial activity of ammoniacal silver nitrate, an endodontic medicament, was tested with Streptococcus faecalis by the serial tube dilution method. Its results indicated that sodium hypochlorite, hydrogen peroxide, and blood had a marked inhibitory effect. However, the presence of dentin, necrotic tissue, saliva, and hydrogen sulfide gas liberated from protein decomposition showed no or little effect on the antibacterial properties of the chemical. Since antiseptics or antibiotics generally may be decomposed by necrotic tissues, these findings suggested that the use of ammoniacal silver nitrate not only may resolve the problem of recalcitrant cases in endodontic treatment but also may simplify the disinfecting procedure for root canals.

Topics: Animals; Anti-Bacterial Agents; Blood; Blood Coagulation; Dental Pulp Cavity; Dentin; Enterococcus faecalis; Gingival Diseases; Goats; Humans; Hydrogen Peroxide; Hydrogen Sulfide; Necrosis; Quaternary Ammonium Compounds; Root Canal Therapy; Saliva; Silver Nitrate; Sodium Hypochlorite