sodium-hypochlorite and Cellulitis

There were examined and treated 52 patients with odontogenic phlegmons of maxillofacial region, from them 25 patients received basic therapy and 27 - additionally sodium hypochrorite, rexod and reamberin during 5 days. It was established that combined use of the abovementioned preparations exerted positive influence upon oxidation-reduction processes, promoted tissue hypoxia and endotoxicosis correction.

Topics: Adolescent; Adult; Cellulitis; Electrochemical Techniques; Free Radicals; Humans; Maxillary Diseases; Middle Aged; Oxidants; Oxidation-Reduction; Sodium Hypochlorite; Young Adult

The paper compares the apparent blood viscosity (BV)-shift rate (SR) curves, by using uni- and multidimensional dispersion analysis. The study has indicated that when admitted to hospital, patients with maxillofacial phlegmons have higher BV due to worse blood rheological and coagulative properties. An analysis of the BV-SR curves has shown that there are the most significant differences between the parameters at moderate and high SR while the differences are frequently insignificant at low SR (on admission, on days 3 and 10). For hemocorrection of increased BV, co-administration of disaggregatory agents is indicated during the treatments proposed. Uni- and multidimensional analyses used to examine the curves of the apparent BV to the individual value of SR and throughout its range are the most informative tools for assessing the quality of treatment in patients with maxillofacial phlegmons and a statistically warranted method for multiple comparisons.

Topics: Blood Transfusion, Autologous; Cellulitis; Combined Modality Therapy; Female; Humans; Jaw Diseases; Male; Oxidants; Oxidation-Reduction; Sodium Hypochlorite

Twenty-five patients with pyoinflammatory maxillofacial diseases treated in an inpatient setting in the Regional Dentistry Clinic of Krasnodar and 8 healthy volunteers were examined. After opening and draining of the purulent focus the patients were divided into 2 groups. Group 1 consisted of 21 patients treated by intravenous 0.04% sodium hypochlorite (SHC) and intravenous infusions of SHC-oxidized autoblood for 2-3 days. Group 2 (6 pts) was treated by intravenous infusions of SHC-oxidized autoblood for 6 days. The criteria of intoxication were erythrocyte resistance tests in hypotonic sodium chloride and at different concentrations of urea in isotonic medium. A new method for evaluating erythrogram deviations from reference values is proposed, which helps adequately assess the severity of intoxication.

Topics: Adolescent; Adult; Blood Transfusion, Autologous; Cell Membrane Permeability; Cellulitis; Erythrocyte Membrane; Face; Hemolysis; Humans; Indicators and Reagents; Jaw; Middle Aged; Osmosis; Oxidation-Reduction; Sensitivity and Specificity; Sodium Hypochlorite; Toxemia; Urea

Sodium hypochlorite, or NaOCl, is one of the most commonly used irrigating solutions in endodontic practice. Its clinically proven antibacterial, solvent and lubricating properties make it a very appealing choice as an intracanal medicament.. The authors present a case of facial hematoma formation after an inadvertent injection of NaOCl into the periapical tissues. The NaOCl solution caused extensive tissue destruction. Management of the condition required the hospitalization, intravenous antibiotic therapy and multiple intraoral surgical incisions to facilitate drainage.. Use of NaOCl must be confined to the root canal system. This report reviews this intracanal medicament's potential toxicity and emphasizes the need for clinicians to remain cognizant of possible problems while using the solution.

Topics: Cellulitis; Cuspid; Ecchymosis; Face; Female; Hematoma; Humans; Medical Errors; Middle Aged; Orbital Diseases; Periapical Tissue; Root Canal Irrigants; Root Canal Obturation; Sodium Hypochlorite

We report the first clinical use of a modified Dakin's solution (0.025% sodium hypochlorite [NaOCl]) to halt the progress of severe cutaneous Vibrio vulnificus infection in a critically ill patient. The regimen used arose from an initial in vitro study designed to examine the sensitivity of Vibrio species to topical antimicrobial agents. Twenty-eight wound isolates were tested against the following eight topical preparations: silver sulfadiazine (Silvadene), nitrofurazone, mupirocin ointment (Bactroban), polymyxin B/bacitracin, mafenide acetate (Sulfamylon), nystatin/Silvadene, nystatin/polymyxin B/bacitracin, and 0.025% NaOCl solution. The results showed that V vulnificus, along with the other 18 Vibrio species tested, was most sensitive to the modified NaOCl solution.

Topics: Administration, Cutaneous; Aged; Anti-Infective Agents, Local; Cellulitis; Critical Illness; Humans; Male; Microbial Sensitivity Tests; Skin Diseases, Bacterial; Sodium Hypochlorite; Vibrio; Vibrio Infections

Complex treatment of 49 patients with phlegmons of the maxillofacial area is described. The UV irradiation of blood and sodium hypochlorite possessing a marked antimicrobial and necrolytic effect included in the treatment of 25 of the patients were found to effectively decrease the endogenous intoxication.

Topics: Administration, Topical; Adolescent; Adult; Blood; Cellulitis; Disinfectants; Facial Dermatoses; Female; Humans; Jaw; Male; Middle Aged; Sodium Hypochlorite; Suppuration; Ultraviolet Rays

The investigation was performed in 39 patients with the severe course of phlegmons of the maxillofacial area. The concentration of the phenyl-pyruvic and para-hydroxyphenyl-pyruvic acids in the diurnal urine was found to be elevated which suggested the disturbed functional state of the liver. Treatment including the ultraviolet irradiation of blood and sodium hypochlorite resulted in rapid normalization of the level of para-hydroxyphenyl-pyruvic acid and in lower concentration of phenyl-pyruvic acid.

Topics: Adult; Amino Acids; Blood; Cellulitis; Circadian Rhythm; Disinfectants; Face; Humans; Middle Aged; Phenylpyruvic Acids; Sodium Hypochlorite; Ultraviolet Rays