sodium-hypochlorite and Bronchial-Hyperreactivity

A 12-year-old girl, with a previous history of bronchial reaction and contact dermatitis to sodium hypochlorite, was referred for root canal treatment. Complete immunologic evaluation revealed a mild hypersensitivity condition, as it was assessed by the RAST investigation to different allergens and the DTH reactivity expressed though migration inhibition test. The absence of a serious immunologic disregulation in the patient's immunologic profile justified the term 'non-allergic hypersensitivity' to sodium hypochlorite to describe the condition.

Topics: Bronchial Hyperreactivity; Cell Migration Inhibition; Chelating Agents; Child; Dermatitis, Contact; Disinfectants; Edetic Acid; Female; Gutta-Percha; Humans; Hypersensitivity; Isotonic Solutions; Peroxides; Radioallergosorbent Test; Root Canal Filling Materials; Root Canal Irrigants; Root Canal Therapy; Sodium Chloride; Sodium Hypochlorite; T-Lymphocytes; Urea; Waxes; Zinc Oxide-Eugenol Cement

Chlorine gas inhalation can lead to temporary mucous membrane irritation, pulmonary edema, and transient bronchospasm. Existence of respiratory sequelae is debated. We report a case of asthma, persisting 2 years after the inhalation of a mixture of sodium hypochlorite and hydrochloric acid. Bronchial histologic findings and transmission electron microscopy examinations showed uncommon abnormalities supporting irritation for cause of this nonimmunologic asthma.

Topics: Accidents, Home; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Chlorine; Female; Humans; Hydrochloric Acid; Sodium Hypochlorite; Time Factors