sodium hydroxide has been researched along with Corneal Neovascularization in 67 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (8.96) | 18.2507 |
2000's | 17 (25.37) | 29.6817 |
2010's | 37 (55.22) | 24.3611 |
2020's | 7 (10.45) | 2.80 |
Authors | Studies |
---|---|
Gao, Q; Grzybowski, A; Han, H; Ji, J; Shentu, X; Tang, X; Tang, Y; Yao, K; Yin, Q; Yu, X | 1 |
Han, Y; Hu, R; Huang, X; Jin, X; Yuan, K; Zhang, Y; Zheng, J | 1 |
Chan, PS; Leung, SSY; Li, Q; To, KKW; Zhang, B | 1 |
Chen, J; Wang, MW; Wu, XY; Xu, JJ; Yao, J | 1 |
Basu, S; Bokara, KK; Damala, M; Kethiri, AR; Rao, CM; Singh, V; Singh, VK | 1 |
Cai, J; Li, Y; Liu, Y; Shu, Y; Wang, W; Wang, X; Wang, Y; Wei, T; Xie, T; Yang, X; Yao, Y; Yin, L; Zhan, P; Zhu, L; Zou, J | 1 |
Andrade, N; Araújo E Silva, PM; Crispim Ribeiro, J; de Moraes, MO; Fechine, FV; Savio, D | 1 |
Choi, H; Fulcher, S; Kim, DK; Oh, JY; Phillips, C; Stock, EM; Won, JK | 1 |
Huang, Z; Lu, Y; Wu, Y; Xue, C | 1 |
Chen, D; Chen, Q; Cheng, R; Larrick, JW; Ma, JX; Mendelson, AR; Qiu, F; Shin, Y; Zhou, K | 1 |
Li, H; Wu, L; Ye, B; Zhu, L | 1 |
Chen, P; Ge, J; Qiu, J; Tang, M; Wang, Q; Wu, Y; Xu, Z; Yang, Y; Yu, J; Yu, K; Zhuang, J | 1 |
Arefian, E; Atyabi, F; Dinarvand, R; Heydari, M; Khonsari, F; Mahbod, M; Shahhosseini, S; Soleimani, M; Zahir-Jouzdani, F | 1 |
Chen, J; Jin, J; Su, SB; Wang, Y; Zhang, J; Zhao, R; Zhou, H | 1 |
Dias, AC; Dias, LC; Fantucci, MZ; Mendes da Silva, LEC; Murashima, AA; Nominato, LF; Rocha, EM | 1 |
Castro-Muñozledo, F; González-Robles, A; Gulias-Cañizo, R; Lagunes-Guillén, A; Sánchez-Guzmán, E | 1 |
Chan, AM; Diaz-Aguilar, D; Duarte, S; Gordon, LK; Law, SM; Sun, MM; Wadehra, M | 1 |
Choi, E; Choi, KR; Han, KE; Jun, RM; Kong, KH; Park, MH | 1 |
Chen, J; Fan, X; Fu, Y; Ge, S; Hu, Y; Li, F; Lu, L; Xu, W; Xu, Y; Zhang, W | 1 |
Basu, S; Bokara, KK; Kethiri, AR; Mishra, DK; Raju, E; Rao, CM; Sangwan, VS; Singh, V | 1 |
Chen, J; Kong, E; Li, X; Liu, X; Su, SB; Wang, Y; Zhang, J; Zhang, Z; Zhu, J | 1 |
Lang, W; Li, X; Lv, X; Ma, J; Yang, H; Zhang, Y; Zhao, S | 1 |
Cai, W; Cheng, R; Gao, G; Gu, X; Li, C; Li, L; Ma, J; Wei, L; Yang, X; Yang, Z; Yao, Y; Zhang, Y | 1 |
Bignami, F; Ferrari, G; Giacomini, C; Rama, P | 1 |
Ambrecht, LA; Bouchard, CS; Bu, P; Nikolic, N; Qiao, L; Sethupathi, P; Vin, AP; Zhai, Y | 1 |
Anderson, C; Wang, S; Zhou, Q | 1 |
Kim, CE; Lee, HS; Lee, JH; Yang, JW | 1 |
Jin, J; Shen, M; Yuan, F; Yuan, Y | 1 |
Aksit, H; Ermis, SS; Sahin, G; Sari, ES; Seyrek, K; Yalcin, B; Yay, A; Yazici, A; Yildiz, O | 1 |
Chen, Z; He, X; Liu, G; Lu, P; Xiao, Y; Zhou, W | 1 |
Bucak, YY; Erdurmus, M; Kükner, AŞ; Önder, Hİ; Simavli, H; Terzi, EH | 1 |
Almaliotis, D; Gounari, E; Karampatakis, V; Koliakos, G; Komnenou, A; Nakos, I; Papakonstantinou, E; Petrakis, S; Thomas, A | 1 |
Guo, Q; Li, X; Tang, W; Zhang, Y; Zhou, H | 1 |
Su, SB; Wang, F; Yang, S; Yang, TS | 1 |
Cejka, C; Cejkova, J; Holan, V; Sykova, E; Trosan, P; Zajicova, A | 1 |
Dan, L; Hong-jie, M; Miao-li, L; Shi-long, Y; Xiang-gui, W; Ying, Z; Yong-ping, L | 1 |
Chen, J; Chu, PH; Jung, SM; Lin, HC; Ma, DH; Shiu, TF; Wang, IJ; Wu, HH; Yeh, LK | 1 |
Li, L; Liu, G; Lu, P; Mukaida, N; Zhang, X | 1 |
Edelhauser, H; Fagerholm, P; Gan, L; Griffith, M; Hackett, JM; Lagali, N; Merrett, K; Sun, Y | 1 |
Ishida, S; Kato, N; Kubota, M; Kubota, S; Kurihara, T; Miyashita, H; Noda, K; Ozawa, Y; Shimmura, S; Tsubota, K; Umezawa, K; Usui, T | 1 |
Chen, P; Wang, Y; Xie, L; Yin, H | 1 |
Fang, D; Fang, J; Lin, Q; Liu, X; Ren, X; Su, SB; Wang, JM; Wen, F; Yang, XP; Yao, X; Zhou, H; Zhou, S | 1 |
Hu, A; Huang, J; Li, S; Li, T; Luo, Y; Ma, W; Pan, J; Tang, S; Wu, J; Yang, J; Yu, H; Zhong, Q | 1 |
Bargagna-Mohan, P; Lau, DL; Mohan, R; Paranthan, RR | 1 |
Budel, V; Mello, GR; Moreira, H; Pizzolatti, ML; Santhiago, MR; Wasilewski, D | 1 |
Ishimori, A; Sakimoto, T; Sawa, M; Sugaya, S | 1 |
Chen, P; Li, C; Wang, Y; Xie, L; Yang, L | 1 |
Adamis, AP; Ambati, BK; Ambati, J; Anand, A; Joussen, AM; Kuziel, WA | 1 |
Hong, HS; Kim, JC; Kwon, YS; Shin, JS; Son, Y | 1 |
Feng, Y; Liao, X; Ma, Q; Zeng, Z; Zhou, Q; Zhu, X | 1 |
Chen, J; Gao, G; Jiang, A; Kuang, W; Li, C; Liu, Z; Luo, L; Ma, JX; Xu, L; Yang, W; Zhang, M; Zhang, Z | 1 |
Gao, G; Gao, Y; Hao, S; Hu, J; Jiang, A; Kuang, W; Li, C; Liu, Z; Wang, Z; Xu, C; Yang, W; Zhang, M | 1 |
Ambati, BK; Amin, S; Jani, PD; Singh, N; Suthar, T | 1 |
Cole, N; Hume, EB; Jalbert, I; Krishnan, R; Vijay, AK; Willcox, MD | 1 |
Jiang, J; Wang, K; Wang, Z; Yan, J; Zeng, Y; Zhu, P | 1 |
Ambati, BK; Amin, S; Jani, PD; Jenkins, C; Kompella, UB; Mo, Y; Raghava, S; Singh, N | 1 |
Dell, S; Joussen, AM; Kociok, N; Muether, PS; Stragies, R; Vossmeyer, D; Zahn, G | 1 |
Correa, L; Croxatto, JO; Gallo, JE; Gatto, S; Lavigne, V; Luengo Gimeno, F | 1 |
Hosseini, H; Mehryar, M; Nejabat, M; Noori, F; Sedaghat, A; Yazdchi, T | 1 |
Amano, S; Hasegawa, G; Ishida, S; Kawakami, Y; Mochimaru, H; Nagahama, Y; Shimmura, S; Tsubota, K; Usui, T; Usui, Y; Yaguchi, T | 1 |
Baba, T; Kuno, K; Li, L; Li, YY; Lu, P; Mukaida, N; Wu, Y; Zhang, X | 1 |
Rehany, U; Waisman, M | 1 |
Dandona, L; Nirankari, VS; Rodrigues, MM | 1 |
Hayashi, N; Nakayasu, K; Okisaka, S | 1 |
Conners, MS; Dunn, MW; Schwartzman, ML; Stoltz, RA; Urbano, F; Vafeas, C | 1 |
Nirankari, VS | 1 |
Hayashi, K; Ishibashi, T | 1 |
67 other study(ies) available for sodium hydroxide and Corneal Neovascularization
Article | Year |
---|---|
Development of mucoadhesive cationic polypeptide micelles for sustained cabozantinib release and inhibition of corneal neovascularization.
Topics: Adhesives; Angiogenesis Inhibitors; Anilides; Animals; Biocompatible Materials; Cations; Cell Proliferation; Cells, Cultured; Corneal Neovascularization; Drug Liberation; Humans; Mice; Micelles; Particle Size; Peptides; Pyridines; Sodium Hydroxide; Surface Properties | 2020 |
Neutrophil extracellular traps promote corneal neovascularization-induced by alkali burn.
Topics: Animals; Burns, Chemical; Cell Movement; Cell Proliferation; Cells, Cultured; Corneal Neovascularization; Extracellular Traps; Eye Burns; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice, Inbred C57BL; Neutrophils; Sodium Hydroxide; TOR Serine-Threonine Kinases | 2020 |
In vivo biocompatibility and efficacy of dexamethasone-loaded PLGA-PEG-PLGA thermogel in an alkali-burn induced corneal neovascularization disease model.
Topics: Alkalies; Animals; Burns, Chemical; Corneal Neovascularization; Dexamethasone; Female; Polyethylene Glycols; Polyglactin 910; Rats; Rats, Sprague-Dawley; Sodium Hydroxide | 2020 |
Gelatin methacryloyl hydrogel eye pad loaded with amniotic extract prevents symblepharon in rabbit eyes.
Topics: Amnion; Animals; Burns, Chemical; Caustics; Corneal Neovascularization; Drug Delivery Systems; Eye; Eye Burns; Gelatin; Hydrogels; Male; Rabbits; Sodium Hydroxide; Transforming Growth Factor beta | 2020 |
Long term observation of ocular surface alkali burn in rabbit models: Quantitative analysis of corneal haze, vascularity and self-recovery.
Topics: Animals; Burns, Chemical; Caustics; Conjunctiva; Cornea; Corneal Injuries; Corneal Neovascularization; Corneal Opacity; Disease Models, Animal; Eye Burns; Follow-Up Studies; Limbus Corneae; Rabbits; Recovery of Function; Sodium Hydroxide; Stem Cell Transplantation; Wound Healing | 2021 |
Protective roles of the TIR/BB-loop mimetic AS-1 in alkali-induced corneal neovascularization by inhibiting ERK phosphorylation.
Topics: Angiogenesis Inhibitors; Animals; Biomarkers; Blotting, Western; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Epithelium, Corneal; Extracellular Signal-Regulated MAP Kinases; Eye Burns; Eye Proteins; Humans; Immunoprecipitation; Lymphangiogenesis; Mice; Mice, Inbred C57BL; Phosphorylation; Pyrrolidines; Real-Time Polymerase Chain Reaction; Sodium Hydroxide; Valine | 2021 |
Effect of Topical Instillation of Pegaptanib Sodium Upon Inflammatory Corneal Neovascularization in Rabbits.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Aptamers, Nucleotide; Caustics; Cornea; Corneal Injuries; Corneal Neovascularization; Disease Models, Animal; Inflammation; Instillation, Drug; Male; Neovascularization, Pathologic; Prednisolone; Rabbits; Sodium Hydroxide; Treatment Outcome; Vascular Endothelial Growth Factor A | 2021 |
Comprehensive Modeling of Corneal Alkali Injury in the Rat Eye.
Topics: Animals; Burns, Chemical; Cornea; Corneal Neovascularization; Corneal Opacity; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Burns; Fibrosis; Gene Expression; Inflammation; Lymphangiogenesis; Macrophages; Male; Neutrophils; Rats; Rats, Inbred Lew; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sodium Hydroxide; Wound Healing | 2017 |
The inhibitory effect of different concentrations of KH902 eye drops on corneal neovascularization induced by alkali burn.
Topics: Administration, Topical; Animals; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Immunohistochemistry; Microscopy, Confocal; Ophthalmic Solutions; Rabbits; Recombinant Fusion Proteins; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2017 |
Anti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway.
Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Antibodies, Monoclonal, Humanized; Burns, Chemical; Cells, Cultured; Corneal Neovascularization; Disease Models, Animal; Epithelium, Corneal; Eye Burns; Humans; Inflammation Mediators; Male; Neovascularization, Pathologic; Rats, Sprague-Dawley; Sodium Hydroxide; Wnt Signaling Pathway | 2018 |
Epigallocatechin gallate inhibits corneal neovascularization in ratalkaline burn model.
Topics: Animals; Burns, Chemical; Catechin; Corneal Neovascularization; Eye Proteins; Inflammation; Male; Neoplasm Proteins; Nerve Growth Factors; Nucleocytoplasmic Transport Proteins; Rats; Serpins; Sodium Hydroxide; Time Factors; Vascular Endothelial Growth Factor A | 2018 |
Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization.
Topics: Animals; Blotting, Western; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; Nuclear Respiratory Factor 1; Pyrazines; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Sodium Hydroxide; Vasodilator Agents | 2018 |
Nanostructured lipid carriers containing rapamycin for prevention of corneal fibroblasts proliferation and haze propagation after burn injuries: In vitro and in vivo.
Topics: Administration, Ophthalmic; Animals; Burns, Chemical; Cell Proliferation; Cells, Cultured; Cornea; Corneal Injuries; Corneal Neovascularization; Corneal Opacity; Disease Models, Animal; Drug Carriers; Drug Compounding; Eye Burns; Fibroblasts; Fibrosis; Humans; Lipids; Male; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Sirolimus; Sodium Hydroxide; Wound Healing | 2019 |
Activation of Toll-like receptor 3 promotes pathological corneal neovascularization by enhancement of SDF-1-mediated endothelial progenitor cell recruitment.
Topics: Administration, Ophthalmic; Animals; Burns, Chemical; Cell Movement; Chemokine CXCL12; Cornea; Corneal Neovascularization; Disease Models, Animal; Endothelial Progenitor Cells; Eye Burns; Fluorescent Antibody Technique, Indirect; Mice; Mice, Inbred C57BL; Poly I-C; Real-Time Polymerase Chain Reaction; Signal Transduction; Sodium Hydroxide; Toll-Like Receptor 3 | 2019 |
Prevention of Corneal Neovascularization by Adenovirus Encoding Human Vascular Endothelial Growth Factor Soluble Receptor (s-VEGFR1) in Lacrimal Gland.
Topics: Adenoviridae; Animals; Burns, Chemical; Corneal Neovascularization; Cytokines; Eye Burns; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Lacrimal Apparatus; Male; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sodium Hydroxide; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2018 |
(-)-Epigallocatechin-3-gallate, reduces corneal damage secondary from experimental grade II alkali burns in mice.
Topics: Alkalies; Animals; Antioxidants; Burns, Chemical; Catechin; Caustics; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cornea; Corneal Neovascularization; Corneal Opacity; Epithelium, Corneal; Eye Burns; Mice; Rabbits; Sodium Hydroxide; Wound Healing | 2019 |
Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model.
Topics: Animals; Antibodies, Blocking; Antigens, CD34; Blotting, Western; Burns, Chemical; Cell Movement; Cells, Cultured; Corneal Neovascularization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Eye Burns; Female; Human Umbilical Vein Endothelial Cells; Humans; Immunotherapy; Limbus Corneae; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Platelet Endothelial Cell Adhesion Molecule-1; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2019 |
Therapeutic effects of three human-derived materials in a mouse corneal alkali burn model.
Topics: Amnion; Animals; Burns, Chemical; Cornea; Corneal Neovascularization; Corneal Opacity; Eye Burns; Humans; Male; Mice, Inbred BALB C; Serum; Sodium Hydroxide | 2019 |
Cholesterol modification of SDF-1-specific siRNA enables therapeutic targeting of angiogenesis through Akt pathway inhibition.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Burns, Chemical; Cell Movement; Cells, Cultured; Chemokine CXCL12; Cholesterol; Corneal Neovascularization; Endothelial Progenitor Cells; Enzyme-Linked Immunosorbent Assay; Eye Burns; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Male; Mesenchymal Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Sodium Hydroxide | 2019 |
Inflammation, vascularization and goblet cell differences in LSCD: Validating animal models of corneal alkali burns.
Topics: Animals; Burns, Chemical; Corneal Diseases; Corneal Neovascularization; Disease Models, Animal; Epithelial Cells; Epithelium, Corneal; Eye Burns; Female; Fluorescent Antibody Technique, Indirect; Goblet Cells; Humans; Immunophenotyping; Inflammation; Keratin-19; Keratin-3; Keratitis; Limbus Corneae; Male; Mice; Mice, Inbred C57BL; Mucins; Rabbits; Sodium Hydroxide | 2019 |
The Effect of Interleukin 38 on Inflammation-induced Corneal Neovascularization.
Topics: Administration, Topical; Animals; Cell Movement; Cells, Cultured; Corneal Neovascularization; Cytokines; Endothelial Cells; Humans; Interleukin-1; Keratitis; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Retina; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2019 |
Blockade of the intermediate-conductance Ca(2+)-activated K+ channel inhibits the angiogenesis induced by epidermal growth factor in the treatment of corneal alkali burn.
Topics: Animals; Blotting, Western; Burns, Chemical; Cell Movement; Cell Proliferation; Cornea; Corneal Neovascularization; Cyclin-Dependent Kinase 4; Disease Models, Animal; Epidermal Growth Factor; Eye Burns; Flavonoids; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Hydroxide; Up-Regulation; Vimentin; Wound Healing | 2013 |
The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Annexin A5; Antimalarials; Apoptosis; Artemisinins; Artesunate; bcl-2-Associated X Protein; Blotting, Western; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Endothelial Cells; Eye Burns; Female; Flow Cytometry; In Situ Nick-End Labeling; Membrane Potential, Mitochondrial; Mitochondria; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium Hydroxide | 2013 |
Alkali burn versus suture-induced corneal neovascularization in C57BL/6 mice: an overview of two common animal models of corneal neovascularization.
Topics: Animals; Burns, Chemical; Corneal Neovascularization; Corneal Stroma; Disease Models, Animal; Eye Burns; Fluorescent Antibody Technique, Indirect; Glycoproteins; Lymphangiogenesis; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nylons; Platelet Endothelial Cell Adhesion Molecule-1; Retrospective Studies; Sodium Hydroxide; Sutures; Time Factors | 2014 |
Effects of activated omental cells on rat limbal corneal alkali injury.
Topics: Animals; Burns, Chemical; Cell Transplantation; Corneal Neovascularization; Corneal Opacity; Disease Models, Animal; Eye Burns; Leukocyte Count; Limbus Corneae; Male; Neutrophils; Omentum; Rats; Rats, Inbred F344; Sodium Hydroxide; Wound Healing | 2014 |
An alkali-burn injury model of corneal neovascularization in the mouse.
Topics: Animals; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Mice; Sodium Hydroxide | 2014 |
Anti-neovascular effect of chondrocyte-derived extracellular matrix on corneal alkaline burns in rabbits.
Topics: Amnion; Animals; Biomarkers; Burns, Chemical; Chondrocytes; Corneal Neovascularization; Disease Models, Animal; Extracellular Matrix; Eye Burns; Humans; Immunoenzyme Techniques; Male; NF-kappa B; Protein Kinase C; Proto-Oncogene Proteins c-akt; Rabbits; Sodium Hydroxide | 2014 |
The effect of TC14012 on alkali burn-induced corneal neovascularization in mice.
Topics: Animals; Burns, Chemical; Conjunctiva; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Gene Expression Regulation; Injections, Intraocular; Male; Matrix Metalloproteinases; Mice; Mice, Inbred BALB C; Oligopeptides; Real-Time Polymerase Chain Reaction; Receptors, CXCR; Receptors, CXCR4; RNA, Messenger; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2014 |
Inhibitory effect of sub-conjunctival tocilizumab on alkali burn induced corneal neovascularization in rats.
Topics: Animals; Antibodies, Monoclonal, Humanized; Burns, Chemical; Conjunctiva; Corneal Neovascularization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Burns; Injections, Intraocular; Male; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-6; Sodium Hydroxide; Vascular Endothelial Growth Factor A; Wound Healing | 2015 |
[Inhibited experimental mouse corneal neovascularization by CCR3 antagonist].
Topics: Animals; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Gene Expression; Humans; Male; Mice; Mice, Inbred BALB C; Random Allocation; Real-Time Polymerase Chain Reaction; Receptors, CCR3; RNA, Messenger; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2014 |
The effect of β receptor blockade through propranolol on corneal neovascularization.
Topics: Adrenergic beta-Antagonists; Animals; Burns, Chemical; Caspase 3; Caustics; Corneal Neovascularization; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Burns; Glucocorticoids; Instillation, Drug; Male; Propranolol; Rats, Wistar; Sodium Hydroxide; Treatment Outcome; Vascular Endothelial Growth Factor A | 2014 |
Mesenchymal stem cells improve healing of the cornea after alkali injury.
Topics: Actins; Alanine Transaminase; Animals; Biomarkers; Burns, Chemical; Corneal Neovascularization; Corneal Opacity; Disease Models, Animal; Eye Burns; Flow Cytometry; Ki-67 Antigen; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rabbits; Re-Epithelialization; Sodium Hydroxide; Vascular Endothelial Growth Factor A; Wound Healing | 2015 |
Transient downregulation of microRNA-206 protects alkali burn injury in mouse cornea by regulating connexin 43.
Topics: Animals; Burns, Chemical; Connexin 43; Cornea; Corneal Injuries; Corneal Neovascularization; Corneal Opacity; Disease Models, Animal; Down-Regulation; HEK293 Cells; Humans; Injections, Intraocular; Keratitis; Male; Mice, Inbred C57BL; MicroRNAs; Oligonucleotides; RNA Interference; RNA, Small Interfering; Sodium Hydroxide; Time Factors; Transfection; Wound Healing | 2015 |
High-mobility group box-1-Toll-Like receptor 4 axis mediates the recruitment of endothelial progenitor cells in alkali-induced corneal neovascularization.
Topics: Animals; Burns, Chemical; Chemokine CXCL12; Cornea; Corneal Injuries; Corneal Neovascularization; Endothelial Progenitor Cells; Eye Burns; Female; HMGB1 Protein; Lipopolysaccharides; Mice, Inbred C57BL; Sodium Hydroxide; Toll-Like Receptor 4 | 2015 |
Transfer of mesenchymal stem cells and cyclosporine A on alkali-injured rabbit cornea using nanofiber scaffolds strongly reduces corneal neovascularization and scar formation.
Topics: Animals; Caustics; Cicatrix; Corneal Injuries; Corneal Neovascularization; Cyclosporine; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Immunosuppressive Agents; Mesenchymal Stem Cell Transplantation; Nanofibers; Rabbits; Sodium Hydroxide; Tissue Scaffolds; Wound Healing | 2016 |
Inhibitory effect of oral doxycycline on neovascularization in a rat corneal alkali burn model of angiogenesis.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Burns, Chemical; Corneal Neovascularization; Dexamethasone; Disease Models, Animal; Doxycycline; Eye Burns; Female; Glucocorticoids; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Treatment Outcome; Wound Healing | 2008 |
Deletion of the FHL2 gene attenuating neovascularization after corneal injury.
Topics: Animals; Blotting, Western; Burns, Chemical; Corneal Injuries; Corneal Neovascularization; Cyclooxygenase 2; Disease Models, Animal; Eye Burns; Gene Deletion; Gene Expression Regulation; Homeodomain Proteins; LIM-Homeodomain Proteins; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Platelet Endothelial Cell Adhesion Molecule-1; Sodium Hydroxide; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2008 |
Enhanced experimental corneal neovascularization along with aberrant angiogenic factor expression in the absence of IL-1 receptor antagonist.
Topics: Animals; Antigens, Differentiation; Burns, Chemical; Cornea; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Fluorescent Antibody Technique, Indirect; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2009 |
Biosynthetic corneal implants for replacement of pathologic corneal tissue: performance in a controlled rabbit alkali burn model.
Topics: Animals; Artificial Organs; Burns, Chemical; Collagen Type III; Cornea; Corneal Neovascularization; Corneal Opacity; Corneal Transplantation; Epithelium, Corneal; Eye Burns; Hydrogels; Methacrylates; Microscopy, Confocal; Microscopy, Electron, Transmission; Models, Animal; Phosphorylcholine; Rabbits; Regeneration; Sodium Hydroxide; Transplantation, Homologous | 2011 |
Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.
Topics: Acetylcysteine; Animals; Antioxidants; Benzamides; Blindness; Burns, Chemical; Chemokine CCL2; Corneal Neovascularization; Cyclohexanones; Deuterium Oxide; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Burns; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Microscopy, Fluorescence; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; Superoxide Dismutase; Superoxide Dismutase-1; Vascular Endothelial Growth Factor A | 2011 |
Inhibitory effect of canstatin in alkali burn-induced corneal neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Burns, Chemical; Collagen Type IV; Corneal Neovascularization; DNA Primers; Enzyme-Linked Immunosorbent Assay; Eye Burns; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
High-mobility group box-1 mediates toll-like receptor 4-dependent angiogenesis.
Topics: Angiogenic Proteins; Animals; Chemotaxis; Cornea; Corneal Neovascularization; Disease Models, Animal; Endothelial Cells; Female; HMGB1 Protein; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Peptide Fragments; Signal Transduction; Sodium Hydroxide; Time Factors; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2011 |
KH906, a recombinant human VEGF receptor fusion protein, is a new effective topical treatment for corneal neovascularization.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Burns, Chemical; Cornea; Corneal Neovascularization; Fluorescein; Humans; Ophthalmic Solutions; Rabbits; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Sodium Hydroxide; Treatment Outcome; Vascular Endothelial Growth Factors | 2011 |
A robust model for simultaneously inducing corneal neovascularization and retinal gliosis in the mouse eye.
Topics: Animals; Blotting, Western; Cornea; Corneal Injuries; Corneal Neovascularization; Disease Models, Animal; Eye Injuries; Glial Fibrillary Acidic Protein; Gliosis; Humans; Immunochemistry; Injections, Intraperitoneal; Macular Degeneration; Mice; Mice, Inbred C57BL; Neuroglia; Platelet Endothelial Cell Adhesion Molecule-1; Retina; Sodium Hydroxide; Withanolides | 2011 |
The effect of subconjunctival bevacizumab on corneal neovascularization, inflammation and re-epithelization in a rabbit model.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Burns, Chemical; Caustics; Corneal Neovascularization; Disease Models, Animal; Endothelium, Corneal; Eye Burns; Inflammation; Injections, Intraocular; Keratitis; Male; Prospective Studies; Rabbits; Random Allocation; Severity of Illness Index; Sodium Hydroxide | 2011 |
Anti-inflammatory effect of IL-6 receptor blockade in corneal alkali burn.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Neutralizing; Burns, Chemical; Cells, Cultured; Chemokine CCL2; Corneal Keratocytes; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Immunoenzyme Techniques; Intercellular Adhesion Molecule-1; Interleukin-6; Keratitis; Male; Mice; Mice, Inbred BALB C; Phosphorylation; Receptors, Interleukin-6; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A | 2012 |
Novel bioactivity of NHERF1 in corneal neovascularization.
Topics: Actins; Animals; Blotting, Western; Burns, Chemical; Cell Cycle; Cell Movement; Cell Proliferation; Corneal Neovascularization; Corneal Ulcer; Eye Burns; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Human Umbilical Vein Endothelial Cells; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; RNA Interference; Sodium Hydroxide; Sodium-Hydrogen Exchangers; Transfection | 2012 |
Sustained inhibition of corneal neovascularization by genetic ablation of CCR5.
Topics: Animals; Burns, Chemical; Cornea; Corneal Injuries; Corneal Neovascularization; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Eye Burns; Fluorescent Antibody Technique, Indirect; Gene Deletion; Intercellular Signaling Peptides and Proteins; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, CCR5; Sodium Hydroxide; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo.
Topics: Animals; Apoptosis; Carrier Proteins; Cell Movement; Cell Proliferation; Corneal Neovascularization; Cytokines; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Growth Substances; Immunosuppressive Agents; In Situ Nick-End Labeling; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirolimus; Sodium Hydroxide; TOR Serine-Threonine Kinases; Umbilical Veins | 2005 |
Characterization of a monoclonal antibody that antagonizes the function of human endostatin.
Topics: Animals; Antibodies, Monoclonal; Cell Adhesion; Cell Movement; Corneal Neovascularization; Endostatins; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; Mice; Mice, Inbred BALB C; Sodium Hydroxide; Structure-Activity Relationship | 2005 |
Plasminogen kringle 5 inhibits alkali-burn-induced corneal neovascularization.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Burns, Chemical; Cattle; Cell Proliferation; Corneal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Eye Burns; Female; Flow Cytometry; Immunohistochemistry; In Situ Nick-End Labeling; Male; Peptide Fragments; Plasminogen; Rabbits; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2005 |
In vivo and in vitro inhibitory effect of amniotic extraction on neovascularization.
Topics: Amnion; Angiogenesis Inhibitors; Animals; Blood Vessels; Blotting, Western; Burns, Chemical; Cell Proliferation; Cells, Cultured; Corneal Neovascularization; Dexamethasone; Endothelium, Vascular; Eye Burns; Eye Proteins; Female; Humans; Nerve Growth Factors; Pilot Projects; Rats; Rats, Sprague-Dawley; Serpins; Sodium Hydroxide; Tetrazolium Salts; Thiazoles; Tissue Extracts; Umbilical Veins | 2006 |
Flt-1 intraceptor induces the unfolded protein response, apoptotic factors, and regression of murine injury-induced corneal neovascularization.
Topics: Animals; Apoptosis; Blotting, Western; Burns, Chemical; Caspase 12; Caspase 3; Cornea; Corneal Neovascularization; DNA-Binding Proteins; Endothelium, Vascular; Eye Burns; Genetic Vectors; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Nuclear Proteins; Receptors, Peptide; Recombinant Fusion Proteins; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; Transcription Factors; Transfection; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; X-Box Binding Protein 1 | 2006 |
Effects of topical administration of 12-methyl tetradecanoic acid (12-MTA) on the development of corneal angiogenesis.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Cornea; Corneal Neovascularization; Dexamethasone; Disease Models, Animal; Eye Burns; Eye Infections, Bacterial; Fatty Acids; Glucocorticoids; Male; Mice; Mice, Inbred BALB C; Pseudomonas Infections; Sodium Hydroxide | 2007 |
A bio-mathematical model of time prediction in corneal angiogenesis after alkali burn.
Topics: Animals; Burns, Chemical; Corneal Neovascularization; DNA, Complementary; Eye Burns; Female; Male; Mice; Models, Biological; Nerve Net; Polymerase Chain Reaction; Random Allocation; RNA; Sodium Hydroxide; Thrombospondins; Vascular Endothelial Growth Factor A | 2007 |
Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis.
Topics: Albumins; Animals; Blotting, Western; Burns, Chemical; Cell Fractionation; Cornea; Corneal Neovascularization; Cytomegalovirus; Endoplasmic Reticulum; Eye Burns; Gene Transfer Techniques; Genetic Vectors; Mice; Mice, Inbred BALB C; Nanoparticles; Plasmids; Receptors, Peptide; Sodium Hydroxide; Vascular Endothelial Growth Factor Receptor-1 | 2007 |
The role of integrin alpha5beta1 in the regulation of corneal neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Cornea; Corneal Neovascularization; Dose-Response Relationship, Drug; Female; Integrin alpha5beta1; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Pyrrolidines; Sodium Hydroxide | 2007 |
Advances in corneal stem-cell transplantation in rabbits with severe ocular alkali burns.
Topics: Animals; Biopsy; Burns, Chemical; Cells, Cultured; Coculture Techniques; Corneal Neovascularization; Disease Models, Animal; Epithelium, Corneal; Eye Burns; Immunohistochemistry; Keratin-12; Keratin-19; Keratin-3; Laser Coagulation; Limbus Corneae; Rabbits; Sodium Hydroxide; Stem Cell Transplantation; Transplantation, Autologous | 2007 |
Bevacizumab inhibits corneal neovascularization in an alkali burn induced model of corneal angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Burns, Chemical; Conjunctiva; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Injections; Rabbits; Sodium Hydroxide; Vascular Endothelial Growth Factor A | 2007 |
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Topics: Animals; Burns, Chemical; CD8-Positive T-Lymphocytes; Corneal Neovascularization; Cytokines; Cytotoxicity Tests, Immunologic; Dendritic Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitopes; Eye Burns; Flow Cytometry; Lymphocyte Depletion; Lymphocyte Subsets; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Sodium Hydroxide; Vaccination; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Protective roles of the fractalkine/CX3CL1-CX3CR1 interactions in alkali-induced corneal neovascularization through enhanced antiangiogenic factor expression.
Topics: ADAM Proteins; ADAMTS1 Protein; Alkalies; Angiogenesis Inhibitors; Animals; Cells, Cultured; Chemokine CX3CL1; Corneal Neovascularization; CX3C Chemokine Receptor 1; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Monocytes; Receptors, Chemokine; Sodium Hydroxide; Thrombospondin 1; Up-Regulation | 2008 |
Suppression of corneal allograft rejection by systemic cyclosporine-A in heavily vascularized rabbit corneas following alkali burns.
Topics: Animals; Burns, Chemical; Cornea; Corneal Injuries; Corneal Neovascularization; Cyclosporine; Eye Burns; Graft Rejection; Injections, Intramuscular; Keratoplasty, Penetrating; Rabbits; Sodium Hydroxide; Transplantation, Homologous | 1994 |
Laser photocoagulation of experimental corneal stromal vascularization. Efficacy and histopathology.
Topics: Animals; Corneal Neovascularization; Corneal Stroma; Disease Models, Animal; Endothelium, Vascular; Fluorescein Angiography; Fluorophotometry; Follow-Up Studies; Laser Coagulation; Rabbits; Sodium Hydroxide | 1993 |
[Immunohistochemical localization of acidic and basic fibroblast growth factor through corneal neovascularization in vivo and in vitro].
Topics: Animals; Cattle; Cells, Cultured; Corneal Neovascularization; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Immunohistochemistry; Rabbits; Sodium Hydroxide | 1996 |
Alkali burn-induced synthesis of inflammatory eicosanoids in rabbit corneal epithelium.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Burns, Chemical; Chromatography, High Pressure Liquid; Cornea; Corneal Neovascularization; Cytochrome P-450 Enzyme System; Disease Models, Animal; Epithelium; Eye Burns; Lipoxygenase; NADP; Rabbits; Sodium Hydroxide; Time Factors; Wound Healing | 1997 |
Laser photocoagulation for corneal stromal vascularization.
Topics: Adult; Aged; Aged, 80 and over; Animals; Corneal Neovascularization; Corneal Stroma; Disease Models, Animal; Female; Fluorophotometry; Humans; Laser Coagulation; Male; Middle Aged; Rabbits; Sodium Hydroxide | 1992 |
In vivo observations on experimental corneal neovascularization with a newly developed macroscope.
Topics: Animals; Burns, Chemical; Cornea; Corneal Neovascularization; Disease Models, Animal; Equipment Design; Eye Burns; Male; Microscopy; Photography; Rabbits; Sodium Hydroxide; Video Recording | 1991 |