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sodium fluoride and Tooth Discoloration

sodium fluoride has been researched along with Tooth Discoloration in 111 studies

Tooth Discoloration: Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)

Research Excerpts

ExcerptRelevanceReference
"To assess use of a two-step dentifrice/gel sequence versus chlorhexidine gluconate mouthrinse on gingivitis prevention after dental prophylaxis."9.27Post-prophylaxis gingivitis prevention with two-step stannous fluoride dentifrice plus whitening gel sequence or chlorhexidine gluconate mouthrinse. ( Anastasia, MK; Garcia-Godoy, C; Gerlach, RW; Gurich, N; Rothrock, J, 2018)
"To assess the effectiveness of three different mouthrinses--chlorhexidine, triclosan + sodium fluoride and chlorhexidine + triclosan + sodium fluoride + zinc chloride--on plaque, calculus, gingivitis and stains and to evaluate the occurrence of adverse effects with these three treatments."9.17Effectiveness of a mouthrinse containing active ingredients in addition to chlorhexidine and triclosan compared with chlorhexidine and triclosan rinses on plaque, gingivitis, supragingival calculus and extrinsic staining. ( Duraiswamy, P; Kulkarni, S; Kumar, S; Patel, S; Tadakamadla, J; Tibdewal, H, 2013)
"The aim of this experimental gingivitis study was to assess the efficacy and safety of two new chlorhexidine (CHX) mouthrinses."9.12Effect of two new chlorhexidine mouthrinses on the development of dental plaque, gingivitis, and discolouration. A randomized, investigator-blind, placebo-controlled, 3-week experimental gingivitis study. ( Brecx, M; Bruhn, G; Heumann, C; Hoffmann, T; Lorenz, K; Netuschil, L, 2006)
"22% sodium fluoride (NaF) on clinical and microbial parameters associated with gingivitis."9.06Effect of toothbrushing with 0.4% stannous fluoride and 0.22% sodium fluoride gel on gingivitis for 18 months. ( Aeppli, DM; Bakdash, MB; Bandt, CL; Pihlstrom, BL; Wolff, LF, 1989)
"To assess use of a two-step dentifrice/gel sequence versus chlorhexidine gluconate mouthrinse on gingivitis prevention after dental prophylaxis."5.27Post-prophylaxis gingivitis prevention with two-step stannous fluoride dentifrice plus whitening gel sequence or chlorhexidine gluconate mouthrinse. ( Anastasia, MK; Garcia-Godoy, C; Gerlach, RW; Gurich, N; Rothrock, J, 2018)
"To assess the effectiveness of three different mouthrinses--chlorhexidine, triclosan + sodium fluoride and chlorhexidine + triclosan + sodium fluoride + zinc chloride--on plaque, calculus, gingivitis and stains and to evaluate the occurrence of adverse effects with these three treatments."5.17Effectiveness of a mouthrinse containing active ingredients in addition to chlorhexidine and triclosan compared with chlorhexidine and triclosan rinses on plaque, gingivitis, supragingival calculus and extrinsic staining. ( Duraiswamy, P; Kulkarni, S; Kumar, S; Patel, S; Tadakamadla, J; Tibdewal, H, 2013)
"The aim of this experimental gingivitis study was to assess the efficacy and safety of two new chlorhexidine (CHX) mouthrinses."5.12Effect of two new chlorhexidine mouthrinses on the development of dental plaque, gingivitis, and discolouration. A randomized, investigator-blind, placebo-controlled, 3-week experimental gingivitis study. ( Brecx, M; Bruhn, G; Heumann, C; Hoffmann, T; Lorenz, K; Netuschil, L, 2006)
"To examine the effect of amine fluoride/stannous fluoride (AmF/SnF(2))-containing dentifrice and mouth rinse on plaque formation and gingivitis as compared with habitual oral hygiene procedures with a regular sodium fluoride (NaF) dentifrice."5.11The effect of a dentifrice and mouth rinse combination containing amine fluoride/stannous fluoride on plaque and gingivitis: a 6-month field study. ( Paraskevas, S; Timmerman, MF; Van der Velden, U; Van der Weijden, GA; Versteeg, PA, 2005)
"22% sodium fluoride (NaF) on clinical and microbial parameters associated with gingivitis."5.06Effect of toothbrushing with 0.4% stannous fluoride and 0.22% sodium fluoride gel on gingivitis for 18 months. ( Aeppli, DM; Bakdash, MB; Bandt, CL; Pihlstrom, BL; Wolff, LF, 1989)
"The interaction of chlorhexidine with dietary chromogens to cause extrinsic dental staining has been exploited in vitro and in vivo to study tooth discoloration and its control."3.72Development of methods to enhance extrinsic tooth discoloration for comparison of toothpastes. 1. Studies in vitro. ( Addy, M; Courtney, M; Newcombe, RG; Pontefract, H; Smith, S, 2004)
"Efficacy was assessed blind-to-treatment using the Gingivitis Bleeding Index (GBI) measured whole-mouth and the composite Lobene Stain Index (LSI) measured on the anterior dentition."2.87Randomized controlled trial evaluating concurrent gingivitis and stain effects of a two-step dentifrice/gel sequence. ( Amini, A; Amini, P; Gerlach, RW, 2018)
"Gingivitis can develop as a reaction to dental plaque."2.82A randomised clinical trial to evaluate the effect of a 67 % sodium bicarbonate-containing dentifrice on 0.2 % chlorhexidine digluconate mouthwash tooth staining. ( Akwagyiram, I; Bosma, ML; Butler, A; Colgan, P; Maclure, R; Yan, N, 2016)
"After three and six weeks' use, the tartar control whitening dentifrice reduced chlorhexidine and tea stain compared to the marketed control."2.70Removal of extrinsic stain using a tartar control whitening dentifrice: a randomized clinical trial. ( Gerlach, RW; White, DJ, 2001)
"Overall, the tartar control whitening dentifrice group experienced an improvement in color, differing statistically from baseline (p < 0."2.70Effects of a tartar control whitening dentifrice on tooth shade in a population with long-standing natural stain. ( Barker, ML; Cordero, RE; Gerlach, RW; Hyde, JD; Jones, MB, 2001)
" Over the 6-month observation period, the sodium hexametaphosphate and the marketed control dentifrices were comparable in terms of adverse event type and severity, and no subject discontinued treatment due to an oral soft tissue adverse event."2.70Anticalculus efficacy and safety of a novel whitening dentifrice containing sodium hexametaphosphate: a controlled six-month clinical trial. ( Baker, R; Gerlach, R; Liu, H; Ramsey, L; Segreto, V; Vastola, K, 2002)

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-19908 (7.21)18.7374
1990's24 (21.62)18.2507
2000's48 (43.24)29.6817
2010's27 (24.32)24.3611
2020's4 (3.60)2.80

Authors

AuthorsStudies
Lima, LC1
Carvalho, AO1
Bezerra, SJC1
Garcia, RM1
Caneppele, TMF1
Borges, AB1
Scaramucci, T1
Schuch, LF1
Schmidt, TR1
Kirschnick, LB1
de Arruda, JAA1
Campagnol, D1
Martins, MAT1
Santos-Silva, AR1
Lopes, MA1
Vargas, PA1
Bagnato, VS1
Kurachi, C1
Guerra, ENS1
Martins, MD1
Gurich, N2
Anastasia, MK3
Grender, J1
Sagel, P1
Fernandes, AJ1
Agnihotri, R1
Liu, H3
Tu, J1
Buelo, A1
Ghassemi, A5
Vorwerk, L4
Hooper, W4
Nathoo, S6
Terézhalmy, G3
He, T5
Eusebio, R1
Milleman, KR4
Milleman, JL5
Young, S3
Parkinson, C2
Mason, S2
Maran, BM1
Vochikovski, L1
de Andrade Hortkoff, DR1
Stanislawczuk, R1
Loguercio, AD1
Reis, A1
Patil, A1
Ling, MR1
Oliveira, BH1
Rajendra, A1
Veitz-Keenan, A1
Niederman, R1
Sagel, PA1
Gerlach, RW7
Amini, P1
Amini, A1
Garcia-Godoy, C1
Rothrock, J1
Porciani, PF1
Grandini, S1
do Carmo Públio, J1
D'Arce, MB1
Ambrosano, GM1
Aguiar, FH1
Lovadino, JR1
Paulillo, LA1
Lima, DA1
Farrell, S2
Grender, JM1
Archila, LR1
Cirigliano, A2
DeSciscio, P2
Patel, V1
Sheth, J1
Hall, C1
Wang, N1
Akwagyiram, I1
Butler, A1
Maclure, R1
Colgan, P1
Yan, N1
Bosma, ML3
DeVizio, W19
Singh, S2
Petrone, DM1
Wachs, GN1
Chaknis, P12
Proskin, HM13
Sreenivasan, P1
Prasad, KV1
Rajesh, G1
Kalyanpur, R1
Bhasker Rao, C1
Duss, C1
Lang, NP1
Cosyn, J1
Persson, GR1
Dunavent, JM1
Fiedler, SK1
Baker, RA1
Kim, YS1
Kwon, HK1
Kim, BI1
García-Godoy, F1
Dibart, S1
Zhang, YP5
Mateo, LR1
Delgado, E1
Paula, A1
dos Santos, PH1
de Oliveira, FG1
Machado, LS1
Neto, DS1
Sundfeld, RH1
Kumar, S1
Patel, S1
Tadakamadla, J1
Tibdewal, H1
Duraiswamy, P1
Kulkarni, S1
Ni, L1
Li, J1
Chang, J1
Sun, L2
Tilliss, TS1
Besho, RW1
Walley, D1
Mankodi, S4
Petrone, ME15
Volpe, AR16
Ayad, F5
De Sciscio, P1
Stewart, B2
De Vizio, W1
Karpinia, K1
Magnusson, I1
Biesbrock, AR2
Walters, PA2
Bartizek, RD4
Giniger, M1
Curtis, JP1
Santarpia, PP1
Petrone, M1
Hunt, SA1
Paraskevas, S2
Danser, MM1
Timmerman, MF2
Van der Velden, U2
Van der Weijden, GA2
Hasturk, H1
Nunn, M1
Warbington, M1
Van Dyke, TE1
Pontefract, H2
Courtney, M2
Smith, S2
Newcombe, RG2
Addy, M8
Soparkar, P1
Rustogi, K4
Sharma, N2
Galustians, HJ1
Qaqish, J1
Nunn, ME1
Chaves, ES1
Gallagher, AC1
Rodriguez, SM1
Ortblad, KM1
Putt, MS1
Versteeg, PA1
Ley, M1
Wagner, T1
Bizhang, M1
Lorenz, K1
Bruhn, G1
Heumann, C1
Netuschil, L1
Brecx, M1
Hoffmann, T1
Claydon, NC1
Adams, G1
Smith, SR1
North, M1
Moran, J2
Chaves, E1
Bsoul, S1
Baker, R3
Browning, WD1
Blalock, JS1
Frazier, KB1
Downey, MC1
Myers, ML1
Li, Y1
Zhang, Y1
Li, X1
Wang, Y1
Zhao, S1
Tang, R1
Terézhalmy, GT1
Barker, ML2
Shern, RJ1
Chow, LC1
Couet, KM1
Kingman, A1
Brown, WE1
Boyd, RL1
Mendieta, C1
Vallcorba, N1
Binney, A1
Jenkins, S3
Newcombe, R3
Joyston-Bechal, S1
Hernaman, N1
Yates, R1
Wade, W1
Yankell, SL3
Emling, RC2
Prencipe, M2
Bollmer, BW1
Sturzenberger, OP1
Vick, V1
Grossman, E1
Sgan-Cohen, HD1
Gat, E1
Schwartz, Z1
Gaffar, A1
Afflitto, J1
Nabi, N1
el-Sayed, SM1
Shereif, AH1
Farghaly, A1
Habib, CM1
Kugel, G1
Marcus, A1
Koertge, TE2
Brooks, CN1
Sarbin, AG1
Powers, D1
Gunsolley, JC1
Kleber, CJ1
Moore, MH1
Nelson, BJ1
Sowinski, J1
Davies, R2
Ellwood, R2
Bradshaw, B2
Demarchi, B2
Khalaf, A3
Galustians, J1
Qaquish, J1
Rustogi, KN1
Sheen, S1
Owens, J1
Warren, DP1
Henson, HA1
Chan, JT1
Ashkenazi, M1
Sarnat, H1
Croll, TP2
Helpin, ML1
Manhold, JH1
Lobene, RR1
Pfarrer, AM1
White, DJ7
Featherstone, JD1
Cox, ER2
Rice, DE1
Dhabhar, DJ1
Isaacs, RL1
Owens, TS1
Hyde, JD1
Jones, MB1
Cordero, RE1
Gerlach, R3
Ramsey, LL2
Ramsey, L2
White, D2
Baig, A1
Kozak, K1
Zoladz, J1
Mahony, L1
Segreto, V1
Vastola, K1
Prater, ME1
Sielski, C1
Berta, RL1
Conforti, N1
da Silva, SM1
de Oliveira, FS1
Lanza, CR1
Machado, MA1
Curtis, SN1
Dooley, CL1
Vreven, J1
Nuuja, T1
Meurman, JH2
Murtomaa, H1
Kortelainen, S1
Metteri, J1
Nuuja, TT1
Murtomaa, HT1
Pesonen, TJ1
Donly, KJ1
O'Neill, M1
Wolff, LF1
Pihlstrom, BL1
Bakdash, MB1
Aeppli, DM1
Bandt, CL1
Leverett, DH1
McHugh, WD1
Jensen, OE1
Bishara, SE1
Denehy, GE1
Goepferd, SJ1
Antalovská, Z1
Skalská, H1
Jüttnerová, V1
Shupe, JL1
Larsen, AE1
Olson, AE1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of a Commercial Dentifrice Containing 10% High Cleaning Silica Base, 0.5% Sodium Phytate and 0.5% Sodium Pyrophosphate on Tooth Whitening: A 8-week Clinical Study in Adults in China[NCT04238429]86 participants (Actual)Interventional2018-05-07Completed
Clinical and Radiographic Evaluation After the Use of Silver Modified Atraumatic Restorative Treatment Versus Atraumatic Restorative Treatment in the Management of Occlusal Caries of Primary Molars in Preschool Children: Randomized Clinical Trial[NCT04354636]Phase 2/Phase 350 participants (Anticipated)Interventional2020-11-01Not yet recruiting
A Study to Evaluate the Effect of a 67% Sodium Bicarbonate Containing Toothpaste on Chlorhexidine Digluconate Tooth Staining[NCT01962493]Phase 4160 participants (Actual)Interventional2013-09-30Completed
Imaging-based Assessment of Oral Biofilm and Gingival Health[NCT05470023]275 participants (Anticipated)Interventional2022-09-01Recruiting
Esthetic Management of Anterior Teeth Utilizing Two Micro Abrasion Treatments: Randomized Clinical Trial[NCT05900817]30 participants (Actual)Interventional2022-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Lobene Stain Index of Stain Area Scores 4 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale. 0= No stain detected; 1= stain covering up to 1/3 of the region; 2= Stain covering >1/3 to 2/3 of the region; 3=Stain covering >2/3 of the region. (NCT04238429)
Timeframe: 4 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients1.1
Negative Control Toothpaste1.32

Lobene Stain Index of Stain Area Scores 8 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale. 0= No stain detected; 1= stain covering up to 1/3 of the region; 2= Stain covering >1/3 to 2/3 of the region; 3=Stain covering >2/3 of the region. (NCT04238429)
Timeframe: 8 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients0.83
Negative Control Toothpaste1.12

Lobene Stain Index of Stain Composite Scores 4 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale and the stain intensity was assessed using 0-3 scale. Lobene Stain Index: Composite for each part is the product of the stain area and intensity scores. The minimum score for Lobene Stain Index: Composite is 0 when both the stain area and intensity scores are 0. The maximum score for Lobene Stain Index: Composite is 9 when both the stain area and intensity scores are 3. (NCT04238429)
Timeframe: 4 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients2.39
Negative Control Toothpaste3.23

Lobene Stain Index of Stain Composite Scores 8 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale and the stain intensity was assessed using 0-3 scale. Lobene Stain Index: Composite for each part is the product of the stain area and intensity scores. The minimum score for Lobene Stain Index: Composite is 0 when both the stain area and intensity scores are 0. The maximum score for Lobene Stain Index: Composite is 9 when both the stain area and intensity scores are 3. (NCT04238429)
Timeframe: 8 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients1.45
Negative Control Toothpaste2.5

Lobene Stain Index of Stain Extent Scores 4 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain intensity was assessed using 0-3 scale. 0= No stain; 1=Light stain(yellow to light brown or gray); 2=Moderate stain(medium brown); 3=Heavy stain(dark brown to black). (NCT04238429)
Timeframe: 4 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients1.35
Negative Control Toothpaste1.64

Lobene Stain Index of Stain Extent Scores 8 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain intensity was assessed using 0-3 scale. 0= No stain; 1=Light stain(yellow to light brown or gray); 2=Moderate stain(medium brown); 3=Heavy stain(dark brown to black). (NCT04238429)
Timeframe: 8 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients0.98
Negative Control Toothpaste1.33

Modified Lobene Stain Index (MLSI) at Week 6

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 6 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 6 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.97
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash1.22

Overall Facial MLSI at Week 3

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 3 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 3 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.27
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.41

Overall Facial MLSI at Week 6

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 6 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 6 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.67
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.96

Overall Gingival and Interproximal MLSI at Week 3

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 3 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 3 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.56
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.73

Overall Gingival and Interproximal MLSI at Week 6

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 6 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 6 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash1.18
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash1.52

Overall Interproximal MLSI at Week 3

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 3 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 3 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.66
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.87

Overall Interproximal MLSI at Week 6

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 6 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 6 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash1.44
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash1.87

Overall MLSI at Week 3

An assessment of the area and intensity of dental stain on the study teeth was performed using the MLSI after usage of 0.2% w/v chlorhexidine digluconate mouthwash for 3 weeks. The intensity of stain was scored on a scale of 0 to 3 (0 - no stain, 1- light stain, 2 - moderate stain, 3 - heavy stain). The area of stain was scored on the following scale: 0 - no stain; 1 - stain up to 1/3 of the area affected; 2- stain between 1/3 and 2/3 of the area affected; and 3 - stain more than 2/3 of area affected. Intensity X Area was thus analyzed on a scale of 0 (best score) to 9 (worst score). (NCT01962493)
Timeframe: Week 3 post treatment administration

InterventionScore on a Scale (Mean)
NaHCO3/NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.46
NaF Toothpaste + Chlorhexidine Digluconate Mouthwash0.59

Reviews

6 reviews available for sodium fluoride and Tooth Discoloration

ArticleYear
    Journal of dentistry, 2023, Volume: 132

    Topics: Carcinoma, Squamous Cell; Charcoal; Color; Head and Neck Neoplasms; Humans; Lichen Planus, Oral; Mou

2023
The Effect of Silver Diamine Fluoride in Preventing Caries in the Primary Dentition: A Systematic Review and Meta-Analysis.
    Caries research, 2019, Volume: 53, Issue:1

    Topics: Cariostatic Agents; Child; Child, Preschool; Controlled Clinical Trials as Topic; Dental Caries; Flu

2019
Chemical agents for the control of plaque and plaque microflora: an overview.
    European journal of oral sciences, 1997, Volume: 105, Issue:5 Pt 2

    Topics: Anti-Infective Agents, Local; Bacteria; Bacterial Adhesion; Cariostatic Agents; Cations; Chemopreven

1997
The efficacy of a dentifrice with caries, plaque, gingivitis, tooth whitening and oral malodor benefits.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:2

    Topics: Cariostatic Agents; Complex Mixtures; Dental Caries; Dental Plaque; Dentifrices; Fluorides; Gingivit

2002
Management of dental staining: can low-abrasive dentifrices play a role?
    Compendium of continuing education in dentistry. (Jamesburg, N.J. : 1995). Supplement, 1997, Volume: 18, Issue:21

    Topics: Animals; Anti-Infective Agents, Local; Chlorhexidine; Dental Deposits; Dentifrices; Humans; Hydrogen

1997
[Fluoride dentifrices].
    L' Information dentaire, 1978, Mar-30, Volume: 60, Issue:13

    Topics: Dental Caries; Dentifrices; Fluorides; Fluorides, Topical; Humans; Sodium Fluoride; Tin Fluorides; T

1978

Trials

76 trials available for sodium fluoride and Tooth Discoloration

ArticleYear
Tooth color change and tolerability evaluation of a hydrogen peroxide whitening strip compared to a strip, paste, and rinse regimen containing plant-based oils and Dead Sea salt.
    American journal of dentistry, 2023, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Color; Humans; Hydrogen Peroxide; Middle Aged; Oils; Oxidants; Sodium Fluoride; T

2023
Evaluation of the efficacy of a charcoal-based tooth whitening dentifrice on coffee stains: an in vitro study.
    Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD, 2023, Volume: 57, Issue:2

    Topics: Charcoal; Coloring Agents; Dentifrices; Humans; Silicon Dioxide; Sodium Fluoride; Staining and Label

2023
Reduction of extrinsic tooth stain by a toothpaste containing 10% high cleaning silica, 0.5% sodium phytate and 0.5% sodium pyrophosphate: an 8-week randomised clinical trial.
    BMC oral health, 2021, 03-11, Volume: 21, Issue:1

    Topics: Adult; Dentifrices; Diphosphates; Humans; Phytic Acid; Silicon Dioxide; Sodium Fluoride; Tooth Bleac

2021
Clinical Study to Determine the Stain Removal Effectiveness of a New Dentifrice Formulation.
    The Journal of clinical dentistry, 2016, Volume: 27, Issue:3

    Topics: Adult; Analysis of Variance; Coloring Agents; Dentifrices; Female; Humans; Male; Prospective Studies

2016
A Randomized Controlled Clinical Trial to Evaluate Extrinsic Stain Removal of a Whitening Dentifrice.
    The Journal of clinical dentistry, 2016, Volume: 27, Issue:4

    Topics: Adult; Analysis of Variance; Coloring Agents; Dentifrices; Female; Humans; Male; Silicon Dioxide; So

2016
Randomized Controlled Trial to Explore the Effect of Experimental Low Abrasivity Dentifrices on Enamel Gloss and Smoothness, and the Build-up of Extrinsic Tooth Stain.
    The Journal of clinical dentistry, 2017, Volume: 28, Issue:2

    Topics: Coloring Agents; Dental Enamel; Dentifrices; Humans; Silicon Dioxide; Sodium Fluoride; Tooth Discolo

2017
A randomized clinical study to evaluate the effect of an ultra-low abrasivity dentifrice on extrinsic dental stain.
    American journal of dentistry, 2017, Volume: 30, Issue:5

    Topics: Coloring Agents; Dentifrices; Double-Blind Method; Humans; Silicon Dioxide; Sodium Fluoride; Tooth B

2017
Tooth sensitivity with a desensitizing-containing at-home bleaching gel-a randomized triple-blind clinical trial.
    Journal of dentistry, 2018, Volume: 72

    Topics: Adolescent; Adult; Carbamide Peroxide; Color; Dentin Desensitizing Agents; Dentin Sensitivity; Femal

2018
An exploratory study to investigate stain build-up with long term use of a stannous fluoride dentifrice.
    American journal of dentistry, 2018, Volume: 31, Issue:2

    Topics: Coloring Agents; Dentifrices; Double-Blind Method; Humans; Phosphates; Sodium Fluoride; Tin Fluoride

2018
Randomized controlled trial evaluating concurrent gingivitis and stain effects of a two-step dentifrice/gel sequence.
    American journal of dentistry, 2018, Volume: 31, Issue:Sp Is A

    Topics: Adult; Coloring Agents; Dentifrices; Gels; Gingivitis; Humans; Hydrogen Peroxide; Sodium Fluoride; T

2018
Post-prophylaxis gingivitis prevention with two-step stannous fluoride dentifrice plus whitening gel sequence or chlorhexidine gluconate mouthrinse.
    American journal of dentistry, 2018, Volume: 31, Issue:Sp Is A

    Topics: Adult; Chlorhexidine; Dentifrices; Double-Blind Method; Gels; Gingivitis; Humans; Mouthwashes; Sodiu

2018
Crossover Clinical Trial of Tablets Containing Sodium Tripolyphosphate on Dental Stain Formation.
    The Journal of clinical dentistry, 2018, Volume: 29, Issue:4

    Topics: Adult; Coloring Agents; Dentifrices; Humans; Polyphosphates; Silicon Dioxide; Sodium Fluoride; Table

2018
Stain Removal Assessment of Two Manual Toothbrushes with an Interproximal Tooth Stain Index.
    The Journal of clinical dentistry, 2015, Volume: 26, Issue:2

    Topics: Adult; Cariostatic Agents; Cuspid; Dentifrices; Female; Follow-Up Studies; Humans; Incisor; Male; Mi

2015
Clinical Effectiveness Evaluation of a New Whitening Dentifrice.
    The Journal of clinical dentistry, 2015, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Aged; Calcium Phosphates; Color; Dentifrices; Female; Follow-Up Studies; Humans;

2015
Extrinsic Stain Removal Effectiveness of a New Whitening Dentifrice.
    The Journal of clinical dentistry, 2015, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Aged; Calcium Phosphates; Dentifrices; Female; Follow-Up Studies; Humans; Incisor

2015
Clinical Study to Assess the Stain Removal Effectiveness of a Tooth Whitening Regimen with Added Whitening Booster.
    The Journal of clinical dentistry, 2015, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Aged; Calcium Phosphates; Dentifrices; Female; Follow-Up Studies; Humans; Male; M

2015
A Randomized Clinical Study Investigating the Stain-Removal Potential of Two Experimental Dentifrices.
    The Journal of clinical dentistry, 2015, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aluminum Oxide; Cariostatic Agents; Cuspid; Dentifrices;

2015
A randomised clinical trial to evaluate the effect of a 67 % sodium bicarbonate-containing dentifrice on 0.2 % chlorhexidine digluconate mouthwash tooth staining.
    BMC oral health, 2016, Aug-25, Volume: 16, Issue:1

    Topics: Chlorhexidine; Dental Plaque; Dentifrices; Double-Blind Method; Humans; Mouthwashes; Sodium Bicarbon

2016
Clinical studies to assess the extrinsic stain prevention and stain removal efficacy of a variant of a commercially available dentifrice containing a new dual silica system.
    The Journal of clinical dentistry, 2008, Volume: 19, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Complex Mixtures; Dentifrices; Double-Blind Method; Female; Follo

2008
Clinical stain removal efficacy of two dentifrices after one and two weeks of use.
    The Journal of clinical dentistry, 2009, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Aged; Cariostatic Agents; Complex Mixtures; Dentifrices; Fluorides; Humans; Middl

2009
A randomized, controlled clinical trial on the clinical, microbiological, and staining effects of a novel 0.05% chlorhexidine/herbal extract and a 0.1% chlorhexidine mouthrinse adjunct to periodontal surgery.
    Journal of clinical periodontology, 2010, Volume: 37, Issue:11

    Topics: Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Chlorhexidine; Chronic Periodontitis; Col

2010
A randomized clinical study to assess the extrinsic staining profiles of stannous- and triclosan-containing dentifrices.
    American journal of dentistry, 2010, Volume: 23 Spec No B

    Topics: Adult; Analysis of Variance; Cariostatic Agents; Dentifrices; Double-Blind Method; Female; Humans; M

2010
Extrinsic stain removal efficacy of a new dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, 0.243% NaF and specially-designed silica for sensitivity relief and whitening benefits as compared to a dentifrice containing 0.3% triclosan, 2% PVM/MA
    American journal of dentistry, 2011, Volume: 24 Spec No A

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Chi-Square Distribution; Dentin Se

2011
Effectiveness of a mouthrinse containing active ingredients in addition to chlorhexidine and triclosan compared with chlorhexidine and triclosan rinses on plaque, gingivitis, supragingival calculus and extrinsic staining.
    International journal of dental hygiene, 2013, Volume: 11, Issue:1

    Topics: Anti-Infective Agents, Local; Cariostatic Agents; Chlorhexidine; Chlorides; Dental Calculus; Dental

2013
Two-week extrinsic stain removal efficacy of a sodium fluoride dentifrice with high cleaning silica: results from two randomized, controlled clinical trials.
    American journal of dentistry, 2012, Volume: 25, Issue:4

    Topics: Adult; Chelating Agents; China; Dentifrices; Double-Blind Method; Female; Humans; Male; Middle Aged;

2012
Use of a whitening dentifrice for control of chlorhexidine stain.
    The journal of contemporary dental practice, 1999, Nov-15, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Chlorhexidine; Dentifrices; Humans; Middle Aged; Sil

1999
Clinical efficacy of an optimized stannous fluoride dentifrice, Part 5: A 3-month study of extrinsic tooth staining, northeast USA.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1997,Winter, Volume: 18 Spec No

    Topics: Adult; Aged; Analysis of Variance; Beverages; Chemistry, Pharmaceutical; Citrates; Dentifrices; Doub

1997
The stain prevention efficacy of two tooth whitening dentifrices.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2002, Volume: 23, Issue:8

    Topics: Adult; Analysis of Variance; Complex Mixtures; Dentifrices; Diphosphates; Double-Blind Method; Drug

2002
The effectiveness of two different battery-powered toothbrushes on whitening through removal of stain.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:5

    Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; Chlorhexidine; Dentifrices; Equipment Des

2002
Clinical comparison of the stain-removal efficacy of a novel liquid whitening gel containing 18% carbamide peroxide and a commercially available whitening dentifrice.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2002, Volume: 23, Issue:11 Suppl 1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Carbamide Peroxide; Complex Mixtures; Dental Devices,

2002
Effect of a combination of amine/stannous fluoride dentifrice and mouthrinse in periodontal maintenance patients.
    Journal of clinical periodontology, 2004, Volume: 31, Issue:3

    Topics: Amines; Cariostatic Agents; Dental Plaque; Dental Plaque Index; Dentifrices; Female; Follow-Up Studi

2004
Efficacy of a fluoridated hydrogen peroxide-based mouthrinse for the treatment of gingivitis: a randomized clinical trial.
    Journal of periodontology, 2004, Volume: 75, Issue:1

    Topics: Adult; Bacterial Typing Techniques; Dental Plaque; Dental Plaque Index; Double-Blind Method; Female;

2004
Development of methods to enhance extrinsic tooth discoloration for comparison of toothpastes. 2. Two-product clinical study.
    Journal of clinical periodontology, 2004, Volume: 31, Issue:1

    Topics: Adult; Analysis of Variance; Chlorhexidine; Complex Mixtures; Cross-Over Studies; Dentifrices; Femal

2004
Comparative tooth whitening and extrinsic tooth stain removal efficacy of two tooth whitening dentifrices: six-week clinical trial.
    The Journal of clinical dentistry, 2004, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Cariostatic Agents; Case-Control Studies; Dentifrices; Female; Follow-Up St

2004
Comparative tooth whitening and extrinsic tooth stain prevention efficacy of a new dentifrice and a commercially available tooth whitening dentifrice: six-week clinical trial.
    The Journal of clinical dentistry, 2004, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Cariostatic Agents; Case-Control Studies; Dentifrices; Female; Follow-Up St

2004
Stain reduction of an integrated oral hygiene system.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2004, Volume: 25, Issue:10 Suppl 1

    Topics: Adult; Aged; Analysis of Variance; Dental Devices, Home Care; Female; Humans; Male; Middle Aged; Sil

2004
Extrinsic tooth stain removal efficacy of a sodium bicarbonate dual-phase dentifrice containing calcium and phosphate in a six-week clinical trial.
    The Journal of clinical dentistry, 2004, Volume: 15, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Dentifrices; Female; Follow-Up Studies; Humans; Hydrogen Pe

2004
The effect of a dentifrice and mouth rinse combination containing amine fluoride/stannous fluoride on plaque and gingivitis: a 6-month field study.
    Journal of clinical periodontology, 2005, Volume: 32, Issue:7

    Topics: Adult; Amines; Dental Plaque; Dental Plaque Index; Dentifrices; Drug Combinations; Female; Gingiviti

2005
Effect of two new chlorhexidine mouthrinses on the development of dental plaque, gingivitis, and discolouration. A randomized, investigator-blind, placebo-controlled, 3-week experimental gingivitis study.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:8

    Topics: Adolescent; Adult; Anti-Infective Agents, Local; Cariostatic Agents; Chlorhexidine; Dental Plaque; D

2006
A comparison of two chlorhexidine gel brushing regimens and a conventional toothpaste brushing regimen for the development of tooth staining over a 6-week period.
    International journal of dental hygiene, 2006, Volume: 4, Issue:4

    Topics: Adult; Anti-Infective Agents, Local; Chlorhexidine; Complex Mixtures; Dentifrices; Diphosphates; Fem

2006
Clinical evaluation of the stain removal efficacy of a novel stannous fluoride and sodium hexametaphosphate dentifrice.
    American journal of dentistry, 2007, Volume: 20, Issue:1

    Topics: Adult; Aged; Complex Mixtures; Dentifrices; Double-Blind Method; Female; Humans; Male; Middle Aged;

2007
Duration and timing of sensitivity related to bleaching.
    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2007, Volume: 19, Issue:5

    Topics: Administration, Topical; Analysis of Variance; Carbamide Peroxide; Cross-Sectional Studies; Dental D

2007
Extrinsic stain removal efficacy of a dual-phase dentifrice.
    American journal of dentistry, 2007, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Dentifrices; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Phosphates

2007
Tooth whitening through the removal of extrinsic stain with two sodium hexametaphosphate-containing whitening dentifrices.
    American journal of dentistry, 2007, Volume: 20, Issue:5

    Topics: Adult; Aged; Dentifrices; Equipment Design; Female; Humans; Male; Middle Aged; Phosphates; Silicic A

2007
Long-term evaluation of a SnF2 gel for control of gingivitis and decalcification in adolescent orthodontic patients.
    International dental journal, 1994, Volume: 44, Issue:1 Suppl 1

    Topics: Adolescent; Child; Dental Plaque; Dental Plaque Index; Female; Gels; Gingivitis; Humans; Male; Mouth

1994
Comparison of 2 chlorhexidine mouthwashes on plaque regrowth in vivo and dietary staining in vitro.
    Journal of clinical periodontology, 1994, Volume: 21, Issue:4

    Topics: Chlorhexidine; Color; Dental Plaque; Dental Plaque Index; Double-Blind Method; Drug Combinations; Hu

1994
Evaluation of a mouthrinse containing chlorhexidine and fluoride as an adjunct to oral hygiene.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Chlorhexidine; Dental Plaque; Dental Plaque Index; Double-Blind Method; Drug Comb

1993
The effect of a mouthrinse containing chlorhexidine and fluoride on plaque and gingival bleeding.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:1

    Topics: Adult; Chlorhexidine; Clinical Protocols; Dental Plaque; Double-Blind Method; Female; Gingival Hemor

1993
The effects of a chlorhexidine toothpaste on the development of plaque, gingivitis and tooth staining.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:1

    Topics: Adult; Chlorhexidine; Dental Plaque; Dental Plaque Index; Double-Blind Method; Gingivitis; Humans; P

1993
A 6-month home usage trial of a 1% chlorhexidine toothpaste (1). Effects on plaque, gingivitis, calculus and toothstaining.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Chlorhexidine; Dental Calculus; Dental Plaque; Dental Plaque Index; Drug Combinat

1993
Clinical study to assess the stain removal efficacy of two tartar control dentifrices and a low abrasive dentifrice.
    The Journal of clinical dentistry, 1994, Volume: 5, Issue:4

    Topics: Adult; Analysis of Variance; Chlorhexidine; Dentifrices; Diphosphates; Double-Blind Method; Drug Com

1994
Reduction of calculus and Peridex stain with Tartar-Control Crest.
    The Journal of clinical dentistry, 1995, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Chlorhexidine; Dental Calculus; Dental Plaque Index; Dentif

1995
The effectiveness of an amine fluoride/stannous fluoride dentifrice on the gingival health of teenagers: results after six months.
    International dental journal, 1996, Volume: 46, Issue:4

    Topics: Adolescent; Amines; Dental Caries; Dental Plaque; Dentifrices; Double-Blind Method; Female; Fluoride

1996
A longitudinal comparison of tooth whitening resulting from dentifrice use.
    The Journal of clinical dentistry, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Cuspid; Dentifrices; Double-Blind Method; Female; Hum

1998
Laboratory assessment of tooth whitening by sodium bicarbonate dentifrices.
    The Journal of clinical dentistry, 1998, Volume: 9, Issue:3

    Topics: Dentifrices; Double-Blind Method; Humans; Hydrogen Peroxide; Silicic Acid; Silicon Dioxide; Sodium B

1998
A six-week clinical efficacy study of a tooth whitening tartar control dentifrice for the removal of extrinsic tooth stain.
    The Journal of clinical dentistry, 1999, Volume: 10, Issue:3 Spec No

    Topics: Adult; Aged; Complex Mixtures; Dental Calculus; Dentifrices; Double-Blind Method; Female; Humans; Ma

1999
A six-week clinical efficacy study of a new dentifrice for the removal of extrinsic tooth stain.
    The Journal of clinical dentistry, 1999, Volume: 10, Issue:3 Spec No

    Topics: Adolescent; Adult; Aged; Complex Mixtures; Dentifrices; Double-Blind Method; Female; Humans; Longitu

1999
A six-week clinical efficacy study of three commercially available dentifrices for the removal of extrinsic tooth stain.
    The Journal of clinical dentistry, 1999, Volume: 10, Issue:3 Spec No

    Topics: Adult; Analysis of Variance; Carbamide Peroxide; Complex Mixtures; Dentifrices; Double-Blind Method;

1999
A six-week clinical efficacy study of four commercially available dentifrices for the removal of extrinsic tooth stain.
    The Journal of clinical dentistry, 1999, Volume: 10, Issue:3 Spec No

    Topics: Adult; Aged; Aluminum Oxide; Analysis of Variance; Complex Mixtures; Dentifrices; Double-Blind Metho

1999
A six-week clinical tooth whitening study of a new calculus-inhibiting dentifrice formulation.
    The Journal of clinical dentistry, 2000, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Complex Mixtures; Dentifrices; Double-Blind Method; Female;

2000
Removal of extrinsic stain using a tartar control whitening dentifrice: a randomized clinical trial.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; Cariostatic Agents; Chlorhexidine; Dental

2001
Maintenance of tooth color after prophylaxis: comparison of three dentifrices.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cariostatic Agents; Color; Colorimetry; Dental

2001
Effects of a tartar control whitening dentifrice on tooth shade in a population with long-standing natural stain.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Cariostatic Agents; Coffee; Color; Dental Calculus; Dentifrices; Diphosphates; Double-B

2001
Extrinsic stain removal with a sodium hexametaphosphate-containing dentifrice: comparisons to marketed controls.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:1

    Topics: Adult; Aluminum Oxide; Analysis of Variance; Dentifrices; Female; Fluorides; Humans; Hydrogen Peroxi

2002
Extrinsic stain prevention with a combination dentifrice containing calcium phosphate surface active builders compared to two marketed controls.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Anti-Infective Agents, Local; Calcium Phosphates; Chlorhexidine;

2002
Anticalculus efficacy and safety of a novel whitening dentifrice containing sodium hexametaphosphate: a controlled six-month clinical trial.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Complex Mixtures; Dental Calculus;

2002
Removal of extrinsic stain using a 7.0% sodium hexametaphosphate dentifrice: a randomized clinical trial.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Dentifrices; Female; Humans; Male; Middle Aged; Phosp

2002
A study to assess the tooth whitening efficacy of a new dentifrice formulation variant containing a special grade of silica: a six-week study on adults.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Complex Mixtures; Dentifrices; Double-Blind Method; Female; Human

2002
Clinical efficacy of a new tooth whitening dentifrice.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Complex Mixtures; Dentifrices; Female; Fluorides; Humans; Male; M

2002
The clinical efficacy of a new tooth whitening dentifrice formulation: a six-month study in adults.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Complex Mixtures; Dentifrices; Double-Blind Method; Female; Fluor

2002
A six-week clinical study to compare the stain removal efficacy of three dentifrices.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Complex Mixtures; Dentifrices; Diphosphates; Double-B

2002
Clinical study to compare extrinsic stain formation in subjects using three dentifrice formulations.
    Compendium of continuing education in dentistry. (Jamesburg, N.J. : 1995). Supplement, 2000, Issue:27

    Topics: Adolescent; Adult; Aged; Air; Analysis of Variance; Complex Mixtures; Dentifrices; Dentin Sensitivit

2000
The effect of a combination of chlorhexidine diacetate, sodium fluoride and xylitol on plaque wet weight and periodontal index scores in military academy cadets refraining from mechanical tooth cleaning for 7-day experimental periods.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:2

    Topics: Adult; Chlorhexidine; Dental Plaque; Dental Plaque Index; DMF Index; Double-Blind Method; Drug Combi

1992
The effect of an experimental chewable antiplaque preparation containing chlorhexidine on plaque and gingival index scores.
    Journal of dental research, 1992, Volume: 71, Issue:5

    Topics: Administration, Oral; Adult; Chlorhexidine; Dental Plaque; Dental Plaque Index; Drug Combinations; G

1992
Effect of toothbrushing with 0.4% stannous fluoride and 0.22% sodium fluoride gel on gingivitis for 18 months.
    Journal of the American Dental Association (1939), 1989, Volume: 119, Issue:2

    Topics: Adult; Bacteria; Dental Plaque; Dentifrices; Female; Fluorides; Gingival Hemorrhage; Gingivitis; Hum

1989
Dental caries and staining after twenty-eight months of rinsing with stannous fluoride or sodium fluoride.
    Journal of dental research, 1986, Volume: 65, Issue:3

    Topics: Adolescent; Child; Dental Caries; DMF Index; Fluorides; Humans; Mouthwashes; Sodium Fluoride; Time F

1986

Other Studies

29 other studies available for sodium fluoride and Tooth Discoloration

ArticleYear
Clinical evidence on a unique two-step stannous fluoride dentifrice and whitening gel sequence.
    American journal of dentistry, 2018, Volume: 31, Issue:Sp Is A

    Topics: Analysis of Variance; Dental Plaque; Dentifrices; Double-Blind Method; Humans; Sodium Fluoride; Tin

2018
Efficacy of tooth bleaching with the prior application of a desensitizing agent.
    Journal of investigative and clinical dentistry, 2015, Volume: 6, Issue:2

    Topics: Animals; Cattle; Color; Dental Enamel; Dentin; Dentin Desensitizing Agents; Fluorides; Hydrogen Pero

2015
The efficacy of a new dentifrice with caries, plaque, gingivitis, calculus, tooth whitening, and oral malodor benefits.
    The Journal of clinical dentistry, 2008, Volume: 19, Issue:3

    Topics: Complex Mixtures; Dental Calculus; Dental Caries; Dental Plaque; Dentifrices; Fluorides; Gingivitis;

2008
Effect of nano-carbonate apatite to prevent re-stain after dental bleaching in vitro.
    Journal of dentistry, 2011, Volume: 39, Issue:9

    Topics: Animals; Apatites; Carbamide Peroxide; Cariostatic Agents; Caseins; Cattle; Color; Crystallography;

2011
A dentifrice with multiple benefits.
    American journal of dentistry, 2011, Volume: 24 Spec No A

    Topics: Dental Caries; Dental Plaque; Dentin Sensitivity; Gingivitis; Humans; Maleates; Polyethylenes; Silic

2011
A multi-tasking dentifrice for the 21st century.
    American journal of dentistry, 2011, Volume: 24 Spec No A

    Topics: Cariostatic Agents; Dental Caries; Dental Plaque; Dentin Desensitizing Agents; Dentin Sensitivity; D

2011
Integrating techniques to restore an adolescent's smile.
    Dentistry today, 2012, Volume: 31, Issue:3

    Topics: Adolescent; Carbamide Peroxide; Cariostatic Agents; Dental Enamel; Esthetics, Dental; Humans; Hydrog

2012
Relative extrinsic stain removal effectiveness of a new battery-powered toothbrush and a flat trim manual toothbrush.
    American journal of dentistry, 2004, Volume: 17 Spec No

    Topics: Analysis of Variance; Animals; Cattle; Color; Complex Mixtures; Dental Enamel; Dentifrices; Diphosph

2004
Development of methods to enhance extrinsic tooth discoloration for comparison of toothpastes. 1. Studies in vitro.
    Journal of clinical periodontology, 2004, Volume: 31, Issue:1

    Topics: Acrylic Resins; Anti-Infective Agents, Local; Chlorhexidine; Color Perception; Colorimetry; Complex

2004
The effect of different fluoridation methods on the red wine staining potential on intensively bleached enamel in vitro.
    American journal of dentistry, 2006, Volume: 19, Issue:2

    Topics: Amines; Carbamide Peroxide; Colorimetry; Dental Enamel; Diamines; Drug Combinations; Fluorides; Fluo

2006
Effects of sequential calcium phosphate-fluoride rinses on dental plaque, staining, fluoride uptake, and caries in rats.
    Journal of dental research, 1984, Volume: 63, Issue:12

    Topics: Animals; Calcium Phosphates; Dental Caries; Dental Enamel; Dental Plaque; Female; Fluorides; Mouthwa

1984
Effect of fluoride application on specular reflectance and stain potential of unfilled and photocured microfilled resin veneering materials.
    Egyptian dental journal, 1994, Volume: 40, Issue:3

    Topics: Acrylic Resins; Chemical Phenomena; Chemistry, Physical; Composite Resins; Crowns; Dental Veneers; D

1994
Preliminary report: laboratory-induced stain removal as assessed by environmental scanning electron microscopy.
    The Journal of clinical dentistry, 1998, Volume: 9, Issue:3

    Topics: Chlorhexidine; Humans; Hydrogen Peroxide; Microscopy, Electron, Scanning; Molar; Silicic Acid; Silic

1998
The effect of toothpaste on the propensity of chlorhexidine and cetyl pyridinium chloride to produce staining in vitro: a possible predictor of inactivation.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:1

    Topics: Acrylic Resins; Analysis of Variance; Anti-Infective Agents, Local; Cetylpyridinium; Chlorhexidine;

2001
Dental hygienist and patient comparisons of fluoride varnishes to fluoride gels.
    Journal of dental hygiene : JDH, 2000,Spring, Volume: 74, Issue:2

    Topics: Attitude of Health Personnel; Attitude to Health; Dental Hygienists; Fluorides, Topical; Gels; Human

2000
Microabrasion of teeth with discoloration resembling hypomaturation enamel defects: four-year follow up.
    The Journal of clinical pediatric dentistry, 2000,Fall, Volume: 25, Issue:1

    Topics: Amelogenesis Imperfecta; Cariostatic Agents; Child; Dental Bonding; Dental Enamel; Dentin Sensitivit

2000
Enamel microabrasion: a new approach.
    Journal of esthetic dentistry, 2000, Volume: 12, Issue:2

    Topics: Cariostatic Agents; Child; Dental Materials; Enamel Microabrasion; Female; Follow-Up Studies; Humans

2000
Influences of directed research and clinical observations on the development of a tartar control whitening dentifrice.
    The Journal of clinical dentistry, 2000, Volume: 11, Issue:3

    Topics: Clinical Trials as Topic; Complex Mixtures; Dental Calculus; Dental Research; Dentifrices; Humans; P

2000
Anticaries profile qualification of an improved whitening dentifrice.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Analysis of Variance; Cariostatic Agents; Dental Calculus; Dental Caries; Dental Enamel; Dentifrices

2001
In vitro studies of the anticalculus efficacy of an improved whitening dentifrice.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Biofilms; Calcium; Cariostatic Agents; Chemistry, Pharmaceutical; Crystallization; Dental Calculus;

2001
Laboratory stain removal and abrasion characteristics of a dentifrice based upon a novel silica technology.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Aluminum Oxide; Animals; Bicarbonates; Cariostatic Agents; Cattle; Chemistry, Pharmaceutical; Color;

2001
A new and improved "dual action" whitening dentifrice technology--sodium hexametaphosphate.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:1

    Topics: Dentifrices; Humans; Phosphates; Sodium Fluoride; Tooth Bleaching; Tooth Discoloration

2002
Laboratory studies on the chemical whitening effects of a sodium hexametaphosphate dentifrice.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:1

    Topics: Adsorption; Carbamide Peroxide; Chlorhexidine; Complex Mixtures; Dental Pellicle; Dentifrices; Dipho

2002
Esthetic improvement following enamel microabrasion on fluorotic teeth: a case report.
    Quintessence international (Berlin, Germany : 1985), 2002, Volume: 33, Issue:5

    Topics: Carbon Compounds, Inorganic; Cariostatic Agents; Child; Complex Mixtures; Dental Enamel; Dentifrices

2002
Cariostatic activity of (1,6-bis-[2-ethylhexylbiguanido]-hexane) in conventional rats.
    Journal of dental research, 1979, Volume: 58, Issue:4

    Topics: Animals; Biguanides; Cariostatic Agents; Chlorhexidine; Chlorides; Dental Caries; Diet, Cariogenic;

1979
Enamel microabrasion: a microscopic evaluation of the "abrosion effect".
    Quintessence international (Berlin, Germany : 1985), 1992, Volume: 23, Issue:3

    Topics: Complex Mixtures; Dental Enamel; Dentifrices; Evaluation Studies as Topic; Humans; Hydrochloric Acid

1992
A conservative postorthodontic treatment of enamel stains.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 1987, Volume: 92, Issue:1

    Topics: Color; Dental Enamel; Humans; Hydrochloric Acid; Orthodontics, Corrective; Silicates; Silicic Acid;

1987
[Prevention of development of tetracycline-induced changes in the teeth of children with the use of sodium fluoride].
    Casopis lekaru ceskych, 1986, Oct-24, Volume: 125, Issue:43

    Topics: Child, Preschool; Dental Enamel Hypoplasia; Female; Humans; Infant; Male; Oxytetracycline; Sodium Fl

1986
Effects of diets containing sodium fluoride on mink.
    Journal of wildlife diseases, 1987, Volume: 23, Issue:4

    Topics: Animals; Bone and Bones; Diet; Female; Male; Mink; Sodium Fluoride; Tissue Distribution; Tooth Disco

1987