Page last updated: 2024-11-04

sodium fluoride and Osteogenic Sarcoma

sodium fluoride has been researched along with Osteogenic Sarcoma in 22 studies

Research Excerpts

ExcerptRelevanceReference
"F-sodium fluoride (NaF) is a bone-seeking agent that can also localize extraosseous calcifying lesions."5.48Unsuspected Metastases to Muscles in Osteosarcoma Detected on 18F-Sodium Fluoride PET-CT. ( Al Kandari, F; Al Maraghy, M; Bakiratharajan, D; Marafi, F; Rasheed, R; Usmani, S, 2018)
"Transforming growth factor beta was shown to be a biphasic stimulator of [3H]thymidine uptake in HOS TE85, with maximal stimulation occurring at 0."5.29Fluoride-stimulated [3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor beta. ( Antich, PP; Pak, CY; Reed, BY; Zerwekh, JE, 1993)
" In the present study, global expression profiling of short noncoding RNAs, in particular miRNAs and snoRNAs, was carried out in sodium fluoride (NaF) treated human osteosarcoma (HOS) cells to understand their possible role in the development of fluorosis."3.81Noncoding RNAs: Possible Players in the Development of Fluorosis. ( Arrigo, P; Bafana, A; Daiwile, AP; Izzotti, A; Kannan, K; Naoghare, PK; Parmar, D; Purohit, HJ; Sivanesan, S, 2015)
"The US National Toxicology Program has shown equivocal evidence of carcinogenic activity of sodium fluoride (NaF) in male F344/N rats based on the occurrence of five osteosarcomas in treated animals."3.69Clastogenic activity of sodium fluoride to rat vertebral body-derived cells in culture. ( Mihashi, M; Tsutsui, T, 1996)
"Patients with osteoblastic metastases from high risk osteosarcoma continue to have a poor prognosis after progression from standard-of-care multi-agent chemotherapy."3.01 ( Anderson, P; Kairemo, K; Macapinlac, HA; Rao, A; Ravizzini, G; Roszik, J; Subbiah, V, 2021)
"F-sodium fluoride (NaF) is a bone-seeking agent that can also localize extraosseous calcifying lesions."1.48Unsuspected Metastases to Muscles in Osteosarcoma Detected on 18F-Sodium Fluoride PET-CT. ( Al Kandari, F; Al Maraghy, M; Bakiratharajan, D; Marafi, F; Rasheed, R; Usmani, S, 2018)
"Osteosarcoma is the most common bone sarcoma in adolescents and children."1.43Unusual Finding of a Tumor Thrombus Arising From Osteosarcoma Detected on 18F-NaF PET/CT. ( Agrawal, A; Purandare, N; Rangarajan, V; Shah, S; Verma, P, 2016)
"Aluminum fluoride (AlF(3)) was included for comparison."1.31Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system. ( Arias, M; Baylink, DJ; Goodwin, C; Lau, KH; Mohan, S, 2002)
"Transforming growth factor beta was shown to be a biphasic stimulator of [3H]thymidine uptake in HOS TE85, with maximal stimulation occurring at 0."1.29Fluoride-stimulated [3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor beta. ( Antich, PP; Pak, CY; Reed, BY; Zerwekh, JE, 1993)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (31.82)18.2507
2000's4 (18.18)29.6817
2010's9 (40.91)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Kairemo, K2
Roszik, J1
Anderson, P1
Ravizzini, G1
Rao, A1
Macapinlac, HA1
Subbiah, V2
Morland, D1
Godard, F1
Lalire, P1
Eymard, JC1
Papathanassiou, D1
Jiang, Y1
Yang, Y2
Wang, H1
Darko, GM1
Sun, D1
Gao, Y2
Usmani, S1
Marafi, F1
Rasheed, R1
Bakiratharajan, D1
Al Maraghy, M1
Al Kandari, F1
Wang, WL1
Huo, L1
Liu, K1
Pei, J1
Ye, Y1
Liu, Y1
Sun, J1
Han, H1
Xu, W1
Wei, Y1
Wu, Y1
Zeng, B1
Zhang, H1
Daiwile, AP1
Sivanesan, S2
Izzotti, A1
Bafana, A2
Naoghare, PK2
Arrigo, P1
Purohit, HJ1
Parmar, D1
Kannan, K2
Verma, P1
Purandare, N1
Agrawal, A1
Shah, S1
Rangarajan, V1
Gandhi, D1
Raynor, W1
Houshmand, S1
Gholami, S1
Emamzadehfard, S1
Rajapakse, CS1
Blomberg, BA1
Werner, TJ1
Høilund-Carlsen, PF1
Baker, JF1
Alavi, A1
Dogan, S1
Günay, H1
Leyhausen, G1
Geurtsen, W1
Brunkhorst, T1
Boerner, AR1
Bergh, S1
Otto, D1
Gratz, FW1
Knapp, WH1
Armour, KJ1
Smith, NW1
Brown, BL1
Dobson, PR1
Glusman, J1
Morris, SA1
Rohde, S1
Chen, G1
Camacho, JA1
Bilezikian, JP1
Reed, BY1
Zerwekh, JE1
Antich, PP1
Pak, CY1
Mihashi, M1
Tsutsui, T1
Bourgoin, SG1
Harbour, D1
Poubelle, PE1
Mitchell, J1
Bansal, A1
Hashimoto, H1
Lau, KH2
Goodwin, C1
Arias, M1
Mohan, S1
Baylink, DJ1
Banting, DW1

Reviews

1 review available for sodium fluoride and Osteogenic Sarcoma

ArticleYear
Evolving Role of Molecular Imaging with (18)F-Sodium Fluoride PET as a Biomarker for Calcium Metabolism.
    Current osteoporosis reports, 2016, Volume: 14, Issue:4

    Topics: Arthritis, Rheumatoid; Back Pain; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone and Bones

2016

Trials

1 trial available for sodium fluoride and Osteogenic Sarcoma

ArticleYear
    Current problems in cancer, 2021, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Bone Neoplasms; Female; Fluorine Radioisotopes; Humans; Lung Neoplasms; Neoplasm

2021

Other Studies

20 other studies available for sodium fluoride and Osteogenic Sarcoma

ArticleYear
Superiority of NaF PET/CT Over Chest CT in a Case of Osteosarcoma.
    Clinical nuclear medicine, 2021, Jul-01, Volume: 46, Issue:7

    Topics: Bone Neoplasms; Fluorine Radioisotopes; Humans; Male; Neoplasm Metastasis; Osteosarcoma; Positron Em

2021
Identification of miR-200c-3p as a major regulator of SaoS2 cells activation induced by fluoride.
    Chemosphere, 2018, Volume: 199

    Topics: Bone Morphogenetic Protein 4; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Fluorides; Hum

2018
Unsuspected Metastases to Muscles in Osteosarcoma Detected on 18F-Sodium Fluoride PET-CT.
    Clinical nuclear medicine, 2018, Volume: 43, Issue:9

    Topics: Adult; Bone Neoplasms; Female; Fluorine Radioisotopes; Humans; Muscle, Skeletal; Osteosarcoma; Posit

2018
Comprehensive molecular imaging of malignant transformation of giant cell tumour of bone reveals diverse disease biology.
    BMJ case reports, 2019, Apr-23, Volume: 12, Issue:4

    Topics: Adult; Bone Neoplasms; Cell Transformation, Neoplastic; Diagnosis, Differential; Female; Fluorodeoxy

2019
Fluoride promotes viability and differentiation of osteoblast-like Saos-2 cells via BMP/Smads signaling pathway.
    Biological trace element research, 2013, Volume: 155, Issue:1

    Topics: Alkaline Phosphatase; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line, Tumor; Cell Sur

2013
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
    Biological trace element research, 2014, Volume: 162, Issue:1-3

    Topics: Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 3; Cell Line, Tumor; Cell Proliferation; Hu

2014
Noncoding RNAs: Possible Players in the Development of Fluorosis.
    BioMed research international, 2015, Volume: 2015

    Topics: Cell Differentiation; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 1 Subunit; Fluorosi

2015
Unusual Finding of a Tumor Thrombus Arising From Osteosarcoma Detected on 18F-NaF PET/CT.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:6

    Topics: Adolescent; Bone Neoplasms; Female; Fluorine Radioisotopes; Humans; Osteosarcoma; Positron Emission

2016
Fluoride-Induced Oxidative and Inflammatory Stress in Osteosarcoma Cells: Does It Affect Bone Development Pathway?
    Biological trace element research, 2017, Volume: 175, Issue:1

    Topics: Bone Development; Cell Line, Tumor; Fluorides; Gene Expression Regulation, Neoplastic; Humans; Infla

2017
Chemical-biological interactions of NaF with three different cell lines and the caries pathogen Streptococcus sobrinus.
    Clinical oral investigations, 2002, Volume: 6, Issue:2

    Topics: 3T3 Cells; Analysis of Variance; Animals; Cariostatic Agents; Cell Division; Cell Line; Cell Surviva

2002
Pretherapeutic assessment of tumour metabolism using a dual tracer PET technique.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:10

    Topics: Adolescent; Bone Neoplasms; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neo

2002
Interleukin-1 beta induces the synthesis of adenylyl cyclase in Swiss 3T3 fibroblasts and MG-63 osteosarcoma cells.
    Biochemical and biophysical research communications, 1995, Jul-17, Volume: 212, Issue:2

    Topics: 3T3 Cells; Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Cycloheximide; Humans; Interleukin-

1995
Opposing influences of dexamethasone and retinoic acid on adenylate cyclase activity in ROS 17/2.8 cells.
    Endocrinology, 1993, Volume: 132, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Amino Acid Sequence; Blotting, Northern; Cell Membr

1993
Fluoride-stimulated [3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor beta.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:1

    Topics: Antibodies; Blotting, Northern; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Hu

1993
Clastogenic activity of sodium fluoride to rat vertebral body-derived cells in culture.
    Mutation research, 1996, Volume: 368, Issue:1

    Topics: Animals; Carcinogens; Cell Survival; Cells, Cultured; Chromosome Aberrations; Male; Mutagens; Osteos

1996
Role of protein kinase C alpha, Arf, and cytoplasmic calcium transients in phospholipase D activation by sodium fluoride in osteoblast-like cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:11

    Topics: ADP-Ribosylation Factors; Biological Transport; Calcium; Cell Line; Cytoplasm; Drug Synergism; Enzym

1996
Dexamethasone increases G alpha q-11 expression and hormone-stimulated phospholipase C activity in UMR-106-01 cells.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Dexamethasone; Enzyme Activation; GTP-Binding P

1997
Differential effects of bacterial toxins on mitogenic actions of sodium fluoride and those of aluminum fluoride in human TE85 osteosarcoma cells.
    Molecular and cellular biochemistry, 2001, Volume: 228, Issue:1-2

    Topics: Alkaline Phosphatase; Aluminum Compounds; Bone Neoplasms; Cell Division; Cholera Toxin; Fluorides; H

2001
Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system.
    Bone, 2002, Volume: 30, Issue:5

    Topics: Aluminum; Aluminum Compounds; Bone Neoplasms; Cell Division; DNA; Fluorides; Fluorine; Gene Expressi

2002
The future of fluoride. An update one year after the National Toxicology Program Study.
    Journal of the American Dental Association (1939), 1991, Volume: 122, Issue:8

    Topics: Animals; Bone Neoplasms; Female; Fluoridation; Fluorosis, Dental; Fractures, Bone; Humans; Male; Mic

1991