sodium fluoride has been researched along with Encephalopathy, Toxic in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, neuroblastoma SH-SY5Y cells were treated with sodium fluoride (NaF), with or without mucolipin synthetic agonist 1 (ML-SA1) or adenovirus TFEB (Ad-TFEB) intervention." | 4.31 | The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity. ( Hu, Z; Ma, Y; Niu, Q; Tang, Y; Xing, H; Xu, P; Xu, W; Zhang, J, 2023) |
| " Using Sprague-Dawley rats developmentally exposed to sodium fluoride (NaF) from pregnancy until 6 months of delivery as in vivo model, we showed that fluoride impaired the cognitive abilities of offspring rats, decreased the density of dendritic spines and the expression of synapse proteins synaptophysin (SYN) and postsynaptic density protein-95 (PSD-95) in hippocampus, suggesting fluoride-induced cognitive deficit associates with synaptic impairment." | 3.88 | ERK1/2-mediated disruption of BDNF-TrkB signaling causes synaptic impairment contributing to fluoride-induced developmental neurotoxicity. ( Chen, J; Dong, L; Li, P; Niu, Q; Wang, A; Xia, T; Xu, C; Zhang, S; Zhao, Q; Zhou, G, 2018) |
| "Fluoride is an element with toxic properties and has been proven to have some adverse effects on many soft tissues, including brain tissue." | 1.72 | Neuromodulatory effects of hesperidin against sodium fluoride-induced neurotoxicity in rats: Involvement of neuroinflammation, endoplasmic reticulum stress, apoptosis and autophagy. ( Bayav, İ; Caglayan, C; Çelik, H; Genç, A; Gür, C; Kandemir, FM; Kandemir, Ö; Yıldız, MO, 2022) |
| "Exposure of neural cells to harmful and toxic factors promotes oxidative stress, resulting in disorders of metabolism, cell differentiation, and maturation." | 1.56 | Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity. ( Baranowska-Bosiacka, I; Dec, K; Gutowska, I; Jakubczyk, K; Lubkowska, A; Maciejewska, D; Skonieczna-Żydecka, K; Skórka-Majewicz, M; Styburski, D; Tarnowski, M; Łukomska, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 7 (53.85) | 2.80 |
| Authors | Studies |
|---|---|
| Yıldız, MO | 1 |
| Çelik, H | 1 |
| Caglayan, C | 1 |
| Kandemir, FM | 1 |
| Gür, C | 1 |
| Bayav, İ | 1 |
| Genç, A | 1 |
| Kandemir, Ö | 1 |
| Han, X | 1 |
| Tang, Y | 6 |
| Zhang, Y | 1 |
| Zhang, J | 7 |
| Hu, Z | 6 |
| Xu, W | 6 |
| Xu, S | 4 |
| Niu, Q | 8 |
| Zhao, Q | 3 |
| Pan, W | 1 |
| Li, J | 1 |
| Yu, S | 1 |
| Liu, Y | 2 |
| Zhang, X | 1 |
| Qu, R | 1 |
| Zhang, Q | 2 |
| Li, B | 1 |
| Yan, X | 1 |
| Ren, X | 1 |
| Qiu, Y | 1 |
| Ma, Y | 2 |
| Xu, P | 2 |
| Xing, H | 2 |
| Dec, K | 1 |
| Łukomska, A | 1 |
| Skonieczna-Żydecka, K | 1 |
| Jakubczyk, K | 1 |
| Tarnowski, M | 1 |
| Lubkowska, A | 1 |
| Baranowska-Bosiacka, I | 1 |
| Styburski, D | 1 |
| Skórka-Majewicz, M | 1 |
| Maciejewska, D | 1 |
| Gutowska, I | 1 |
| Tu, W | 1 |
| Han, L | 1 |
| Wang, Q | 1 |
| Chen, P | 1 |
| Zhang, S | 3 |
| Wang, A | 3 |
| Zhou, X | 1 |
| Chen, J | 2 |
| Xia, T | 2 |
| Zhou, G | 2 |
| Li, P | 2 |
| Xu, C | 2 |
| Dong, L | 2 |
| Tian, Z | 1 |
| Luo, C | 1 |
| Liu, L | 1 |
| Atmaca, N | 1 |
| Atmaca, HT | 1 |
| Kanici, A | 1 |
| Anteplioglu, T | 1 |
| Zhu, WJ | 1 |
| Xu, XH | 1 |
| Zhang, ZG | 1 |
| Lou, DD | 1 |
| Guan, ZZ | 1 |
| Liu, YJ | 1 |
| Liu, YF | 1 |
| Zhang, KL | 1 |
| Pan, JG | 1 |
| Pei, JJ | 1 |
13 other studies available for sodium fluoride and Encephalopathy, Toxic
| Article | Year |
|---|---|
Neuromodulatory effects of hesperidin against sodium fluoride-induced neurotoxicity in rats: Involvement of neuroinflammation, endoplasmic reticulum stress, apoptosis and autophagy.
Topics: Animals; Apoptosis; Autophagy; Endoplasmic Reticulum Stress; Hesperidin; Neuroinflammatory Diseases; | 2022 |
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Topics: Adenosine Triphosphatases; Animals; Autophagy; Fluorides; Hydrogen-Ion Concentration; Lysosomes; Neu | 2022 |
Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.
Topics: Animals; Arsenic; Autophagy; Beclin-1; Drinking Water; Female; Fluorides; Neurons; Neurotoxicity Syn | 2022 |
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Topics: Animals; Autophagy; Cell Line, Tumor; Fluorides; Humans; Lysosomes; Neuroblastoma; Neurotoxicity Syn | 2023 |
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Topics: Animals; Autophagy; Cell Line, Tumor; Fluorides; Humans; Lysosomes; Neuroblastoma; Neurotoxicity Syn | 2023 |
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Topics: Animals; Autophagy; Cell Line, Tumor; Fluorides; Humans; Lysosomes; Neuroblastoma; Neurotoxicity Syn | 2023 |
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Topics: Animals; Autophagy; Cell Line, Tumor; Fluorides; Humans; Lysosomes; Neuroblastoma; Neurotoxicity Syn | 2023 |
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Topics: Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Fluorides; Humans; | 2023 |
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Topics: AMP-Activated Protein Kinases; Animals; Fluorides; Humans; Mitochondria; Mitophagy; Neuroblastoma; N | 2023 |
Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity.
Topics: Animals; Brain; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Glutathione | 2020 |
Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans | 2018 |
ERK1/2-mediated disruption of BDNF-TrkB signaling causes synaptic impairment contributing to fluoride-induced developmental neurotoxicity.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Line; Cognition; Dendritic Spines; Female; Humans; | 2018 |
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cell Survival; Child; Cognition; Envir | 2019 |
Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Brain; Chemical and Drug Induced Liver Injury; D | 2014 |
Effect of fluoride on calcium ion concentration and expression of nuclear transcription factor kappa-B ρ65 in rat hippocampus.
Topics: Animals; CA3 Region, Hippocampal; Calcium; Dose-Response Relationship, Drug; Fluoride Poisoning; Flu | 2011 |
The influence of chronic fluorosis on mitochondrial dynamics morphology and distribution in cortical neurons of the rat brain.
Topics: Animals; Blotting, Western; Cerebral Cortex; Dynamins; Female; Fluorosis, Dental; Immunohistochemist | 2013 |