Page last updated: 2024-11-04

sodium fluoride and Disease Exacerbation

sodium fluoride has been researched along with Disease Exacerbation in 42 studies

Research Excerpts

ExcerptRelevanceReference
"18F-Sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) are promising novel biomarkers of disease activity in aortic stenosis."9.1918F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis. ( Boon, NA; Chin, CW; Cowie, WJ; Dweck, MR; Fletcher, A; Jenkins, WS; Malley, TS; Newby, DE; Pessotto, R; Pringle, MA; Richardson, H; Rudd, JH; Tsampasian, V; van Beek, EJ; Vesey, AT; Wallace, WA, 2014)
"The present investigation was performed to examine if triclosan and a copolymer, incorporated in a dentifrice and used by periodontitis-susceptible subjects could influence clinical symptoms characteristic of recurrent periodontitis."9.08The use of a triclosan/copolymer dentifrice may retard the progression of periodontitis. ( Furuichi, Y; Lindhe, J; Ramberg, P; Rosling, B; Volpe, AR; Wannfors, B, 1997)
"A significant majority of atherosclerotic plaque ruptures occur in coronary arteries exhibiting none or only modest luminal narrowing on coronary angiography."6.49Targeted PET/CT imaging of vulnerable atherosclerotic plaques: microcalcification with sodium fluoride and inflammation with fluorodeoxyglucose. ( Chen, W; Dilsizian, V, 2013)
"18F-Sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) are promising novel biomarkers of disease activity in aortic stenosis."5.1918F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis. ( Boon, NA; Chin, CW; Cowie, WJ; Dweck, MR; Fletcher, A; Jenkins, WS; Malley, TS; Newby, DE; Pessotto, R; Pringle, MA; Richardson, H; Rudd, JH; Tsampasian, V; van Beek, EJ; Vesey, AT; Wallace, WA, 2014)
"The present investigation was performed to examine if triclosan and a copolymer, incorporated in a dentifrice and used by periodontitis-susceptible subjects could influence clinical symptoms characteristic of recurrent periodontitis."5.08The use of a triclosan/copolymer dentifrice may retard the progression of periodontitis. ( Furuichi, Y; Lindhe, J; Ramberg, P; Rosling, B; Volpe, AR; Wannfors, B, 1997)
"18F-sodium fluoride (18F-NaF) has been used to access aortic stenosis in clinical research setting."3.96Aortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients. ( Abrunhosa, A; Castelo-Branco, M; Chichorro, N; de Lima, JP; Domingues, C; Gonçalves, L; João Ferreira, M; Oliveira-Santos, M; Silva, R, 2020)
"The aim of this exploratory double-blinded, randomized, cross-over, in situ study was to compare the effects of various model parameters ('intervention', 'brushing', 'position') on enamel caries lesions in a dose-response model."2.80The effect of various model parameters on enamel caries lesions in a dose-response model in situ. ( Dörfer, CE; Gninka, B; Heldmann, P; Meyer-Lueckel, H; Paris, S; Wierichs, RJ, 2015)
"A significant majority of atherosclerotic plaque ruptures occur in coronary arteries exhibiting none or only modest luminal narrowing on coronary angiography."2.49Targeted PET/CT imaging of vulnerable atherosclerotic plaques: microcalcification with sodium fluoride and inflammation with fluorodeoxyglucose. ( Chen, W; Dilsizian, V, 2013)
" Oral examinations were conducted before radiotherapy, after dosage of 2000 cGy irradiation, immediately after the termination of radiotherapy, and 1 month and 6 months after termination of the radiotherapy."1.36Progress of oral sequelae during head-neck radiotherapy. ( Deng, J; Gao, XJ; Li, NY; Lu, HJ; Sun, HB, 2010)
"Furthermore, progressive severe dental caries can present a dilemma for the clinician in affected individuals, despite intensive preventive and restorative therapy."1.31Submandibular gland aplasia and progressive dental caries: a case report. ( Fracaro, MS; Hallett, KB; Linnett, VM; Savage, NW, 2002)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (7.14)18.2507
2000's8 (19.05)29.6817
2010's26 (61.90)24.3611
2020's5 (11.90)2.80

Authors

AuthorsStudies
Kwiecinski, J1
Tzolos, E1
Fletcher, AJ1
Nash, J1
Meah, MN1
Cadet, S1
Adamson, PD1
Grodecki, K1
Joshi, N1
Williams, MC1
van Beek, EJR1
Lai, C1
Tavares, AAS1
MacAskill, MG1
Dey, D1
Baker, AH1
Leipsic, J1
Berman, DS1
Sellers, SL1
Newby, DE5
Dweck, MR4
Slomka, PJ1
Domingues, C1
João Ferreira, M1
Silva, R1
Oliveira-Santos, M1
Chichorro, N1
de Lima, JP1
Gonçalves, L1
Castelo-Branco, M1
Abrunhosa, A1
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J3
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Ma, Q1
Wang, J4
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Wang, Y2
Meng, J1
Chen, G3
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X6
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y4
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Li, C1
Chen, W3
Hu, X1
Zhang, F1
Wei, H1
Wang, Z1
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q2
Lyu, Y1
Huang, J1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
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Bellingham, G1
Singh, M2
Waseem, R1
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Glurich, I1
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Acharya, A1
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Goetchius, E1
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Ploutz-Snyder, R1
Guilliams, M1
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Ploutz-Snyder, LL1
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Gjestad, R1
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Nordahl, SHG1
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Shah, PD1
Toy, W1
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Shen, R1
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Zamora, S1
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Covey, A1
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Lanman, RB1
Solit, DB1
Robson, ME1
Lacouture, ME1
Brogi, E1
Reis-Filho, JS1
Moynahan, ME1
Scaltriti, M1
Chandarlapaty, S1
Papouskova, K1
Moravcova, M1
Masrati, G1
Ben-Tal, N1
Sychrova, H1
Zimmermannova, O1
Fang, J1
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Luo, T2
Su, H1
Tsetseris, L1
Anthopoulos, TD1
Liu, SF1
Zhao, K1
Sacan, O1
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Mukherjee, S1
Alexander, R1
Mondal, A1
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Jiang, F1
Yuan, D1
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Hong, M1
Chen, K1
Hussain, M1
Razi, SS1
Yildiz, EA1
Zhao, J1
Yaglioglu, HG1
Donato, MD1
Jiang, J1
Jamil, MI1
Zhan, X1
Chen, F1
Cheng, D1
Wu, CT1
Utsunomiya, T1
Ichii, T1
Fujinami, S1
Nakajima, K1
Sanchez, DM1
Raucci, U1
Ferreras, KN1
Martínez, TJ1
Mordi, NA1
Mordi, IR1
Singh, JS1
McCrimmon, RJ1
Struthers, AD1
Lang, CC1
Wang, XW1
Yuan, LJ1
Yang, Y1
Chen, WF1
Luo, R1
Yang, K1
Amarasiri, SS1
Attanayake, AP1
Arawwawala, LDAM1
Jayatilaka, KAPW1
Mudduwa, LKB1
Ogunsuyi, O2
Akanni, O1
Alabi, O1
Alimba, C1
Adaramoye, O1
Cambier, S1
Eswara, S1
Gutleb, AC1
Bakare, A1
Gu, Z1
Cong, J1
Pellegrini, M1
Palmieri, S1
Ricci, A1
Serio, A1
Paparella, A1
Lo Sterzo, C1
Jadeja, SD1
Vaishnav, J1
Mansuri, MS1
Shah, C1
Mayatra, JM1
Shah, A1
Begum, R1
Song, H2
Lian, Y1
Wan, T1
Schultz-Lebahn, A1
Skipper, MT1
Hvas, AM1
Larsen, OH1
Hijazi, Z1
Granger, CB1
Hohnloser, SH1
Westerbergh, J1
Lindbäck, J1
Alexander, JH1
Keltai, M1
Parkhomenko, A1
López-Sendón, JL1
Lopes, RD1
Siegbahn, A1
Wallentin, L1
El-Tarabany, MS1
Saleh, AA1
El-Araby, IE1
El-Magd, MA1
van Ginkel, MPH1
Schijven, MP1
van Grevenstein, WMU1
Schreuder, HWR1
Pereira, EDM1
da Silva, J1
Carvalho, PDS1
Grivicich, I1
Picada, JN1
Salgado Júnior, IB1
Vasques, GJ1
Pereira, MADS1
Reginatto, FH1
Ferraz, ABF1
Vasilenko, EA1
Gorshkova, EN1
Astrakhantseva, IV1
Drutskaya, MS1
Tillib, SV1
Nedospasov, SA1
Mokhonov, VV1
Nam, YW1
Cui, M1
Orfali, R1
Viegas, A1
Nguyen, M1
Mohammed, EHM1
Zoghebi, KA1
Rahighi, S1
Parang, K1
Patterson, KC1
Kahanovitch, U1
Gonçalves, CM1
Hablitz, JJ1
Staruschenko, A1
Mulkey, DK1
Olsen, ML1
Gu, L1
Cao, X1
Mukhtar, A1
Wu, K1
Zhang, YY1
Zhu, Y1
Lu, DZ1
Dong, W1
Bi, WJ1
Feng, XJ1
Wen, LM1
Sun, H1
Qi, MC1
Chang, CC1
Dinh, TK1
Lee, YA1
Wang, FN1
Sung, YC1
Yu, PL1
Chiu, SC1
Shih, YC1
Wu, CY1
Huang, YD1
Lu, TT1
Wan, D1
Sakizadeh, J1
Cline, JP1
Snyder, MA1
Kiely, CJ1
McIntosh, S1
Jiang, X1
Cao, JW1
Zhao, CK1
Yang, R1
Zhang, QY1
Chen, KJ2
Liu, H1
He, Z1
Chen, B1
Wu, J1
Du, X1
Moore, J1
Blank, BR1
Eksterowicz, J1
Sutimantanapi, D1
Yuen, N1
Metzger, T1
Chan, B1
Huang, T1
Chen, X1
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Ramanathan, R1
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Le, VH1
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Gong, Q1
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Zhou, G1
Toma, C1
Khandhar, S1
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D'Auria, SJ1
Tu, TM1
Jaber, WA1
Cho, J2
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Razek, S1
Choi, YH1
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Xie, S1
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Bates, FS1
Lodge, TP1
Hao, Y1
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Liu, JJ1
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Do, T1
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Miller Iii, TF1
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Qiang, L1
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Cui, YH1
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Li, G1
Hou, G1
Cui, J1
Xie, H1
Sun, Z1
Fang, Z1
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Hallal-Calleros, C1
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Kim, MJ1
Han, C1
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Park, HJ1
Ding, D1
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Rothenberger, C1
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Dharuman, V1
Feng, J2
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Situ, B1
An, T1
Zheng, L1
Augusto, S1
Ratola, N1
Tarín-Carrasco, P1
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Turco, M1
Schuhmacher, M1
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Costa, C1
Syed, A1
Marraiki, N1
Al-Rashed, S1
Elgorban, AM1
Yassin, MT1
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Nanan, S1
Sorokina, KN1
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Gromov, NV1
Ogorodnikova, OL1
Parmon, VN1
Ye, J1
Liao, W1
Zhang, P1
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Cai, Y1
Li, F1
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Omari, KW1
Adeosun, WA1
Asiri, AM1
Marwani, HM1
Barral, M1
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Soyer, P1
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Namburath, M1
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Moscariello, C1
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Alappat, BJ1
Sreekrishnan, TR1
Volpin, F1
Woo, YC1
Kim, H1
Freguia, S1
Jeong, N1
Choi, JS1
Phuntsho, S1
Shon, HK1
Domínguez-Zambrano, E1
Pedraza-Chaverri, J1
López-Santos, AL1
Medina-Campos, ON1
Cruz-Rivera, C1
Bueno-Hernández, F1
Espinosa-Cuevas, A1
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Dalgediene, I1
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Köhler, R1
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Militz, H1
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Heath, EI1
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Martines de Souza, B1
Vertuan, M1
Buzalaf, MAR1
Magalhães, AC2
Høilund-Carlsen, PF2
Moghbel, MC1
Gerke, O1
Alavi, A3
Raggi, P1
Prandini, N1
Ligabue, G1
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Milic, J1
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Leng, H1
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Brown, OS1
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Eversole, SL2
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Faller, RV2
Doris, MK1
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Babajko, S1
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Blomberg, BA1
Werner, TJ1
Baker, JF1
da Silva, CV1
Ramos-Oliveira, TM1
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de Freitas, PM1
Schlueter, N2
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Ganss, C2
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Della Chiesa, A1
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Reznik, DA1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A PHASE 2, OPEN-LABEL, SINGLE-ARM STUDY OF 18F-SODIUM FLUORIDE PET/CT BONE IMAGING IN ENZALUTAMIDE-TREATED CHEMOTHERAPY-NAÏVE PATIENTS WITH BONE-METASTATIC CASTRATION-RESISTANT PROSTATE CANCER[NCT02384382]Phase 223 participants (Actual)Interventional2015-11-30Completed
SALTIRE II: Bisphosphonates and RANKL Inhibition in Aortic Stenosis[NCT02132026]Phase 2152 participants (Actual)Interventional2014-11-12Completed
An Observational PET/CT Study Examining the Role of Active Valvular Calcification and Inflammation in Patients With Aortic Stenosis[NCT01358513]121 participants (Actual)Observational2010-07-31Completed
Comparison of MI Paste Plus and Resin Infiltration in Improvement of White Spot Lesions Following Fixed Orthodontic Treatment: A Randomized Controlled Trial[NCT05733676]62 participants (Anticipated)Interventional2023-05-30Recruiting
Fluoride Varnish Trial in High Caries Preschoolers[NCT00067353]Phase 3500 participants Interventional2003-11-30Completed
Radiographic Progression of Sealed and Infiltrated Caries Lesions in Vivo[NCT01417832]Phase 2/Phase 337 participants (Actual)Interventional2008-01-31Completed
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes[NCT01589991]Phase 124 participants (Actual)Interventional2011-01-31Completed
Effects of a Toothpaste Containing 0.3% Triclosan in the Maintenance Phase of Peri-implantitis Treatment.[NCT03191721]Phase 3102 participants (Actual)Interventional2010-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Heterogeneity of Response Across All Bone Lesions as Measured by Global Heterogeneity of NaF Standardized Uptake (SUVhetero) Score at Third 18F-NaF PET/CT Imaging (NaF-3) Schedule

Global SUVhetero score:Sum of(SUVmean of each lesion minus global SUVmean of all lesion)^2/number of lesions,measure of heterogeneity of tumor activity across all bone lesions.SUVmean(mean NaF uptake)indicated average activity of each lesions.Real limits for SUVhetero score ranged:0(minimum) to infinite(maximum).Higher global SUVhetero score:more heterogeneity in bone lesion activity.NaF-3 performed on any of these 1)PSA progression(increase of>=25% and absolute increase of>=2.0ng/mL above nadir);2)bone PD(appearance of>=2 new lesions after screening assessed by 99mTc-MDP bone scintigraphy);3)soft tissue PD(RECIST1.1);4)clinically relevant progression by investigator;5)at 2years without progression after treatment initiation.PD perRECIST1.1:>=20%increase in sum of diameters of target lesions,(reference smallest sum on study,this included baseline sum if that is smallest on study),relative increase of20%,sum of diameters indicated absolute increase of>=5mm,appearance of>=1 new lesions. (NCT02384382)
Timeframe: At NaF-3 schedule: at time of PSA, or radiographic(bone or soft tissue), or clinically relevant progression, or at 2years without progression after treatment initiation, whichever occurred first(From first dose of study drug up to maximum of 34.1 months)

Interventionunit on SUVhetero score (Mean)
Enzalutamide 160 mg (18F-NaF PET/CT)3.9

Percentage of Participants With at Least (>=) 1 Responding Bone Lesion Assessed by Total Sodium Fluoride (NaF) Standardized Uptake Value [SUVtotal] at Third 18F-NaF PET/CT Imaging (NaF-3) Schedule

Bone lesion responded: if its change from baseline in SUVtotal is below limit of agreement (LOA, no specific value, based upon test/retest analysis using software). SUVtotal: total NaF uptake,indicated tumor burden across all bone lesions/in individual lesions reflecting bone-metastatic prostate cancer.NaF-3 performed on any of these: 1) prostate-specific antigen (PSA) progression(increase of >=25% and absolute increase of >=2.0 ng/mL above nadir); 2) bone progressive disease(PD)(appearance of >=2 new lesions after screening assessed by technetium Tc 99m medronate [99mTc-MDP] bone scintigraphy); 3) soft tissue PD; 4) clinically relevant progression by investigator; 5) at 2 years without progression after treatment initiation. PD, RECIST1.1:>=20% increase in sum of diameters of target lesions,(reference smallest sum on study, included baseline sum if that is smallest on study),relative increase of 20%,sum of diameters indicated absolute increase of >=5mm, appearance of >=1 new lesions. (NCT02384382)
Timeframe: At NaF-3 schedule: at time of PSA, or radiographic(bone or soft tissue), or clinically relevant progression, or at 2years without progression after treatment initiation, whichever occurred first(From first dose of study drug up to maximum of 34.1 months)

Interventionpercentage of participants (Number)
Enzalutamide 160 mg (18F-NaF PET/CT)100.0

Reviews

5 reviews available for sodium fluoride and Disease Exacerbation

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Evolving Role of PET in Detecting and Characterizing Atherosclerosis.
    PET clinics, 2019, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Contrast Media; Coronary Artery Disease; Disease Models, An

2019
Targeted PET/CT imaging of vulnerable atherosclerotic plaques: microcalcification with sodium fluoride and inflammation with fluorodeoxyglucose.
    Current cardiology reports, 2013, Volume: 15, Issue:6

    Topics: Calcinosis; Coronary Angiography; Coronary Artery Disease; Disease Progression; Early Diagnosis; Fem

2013
Identification of early vascular calcification with (18)F-sodium fluoride: potential clinical application.
    Expert review of cardiovascular therapy, 2016, Volume: 14, Issue:6

    Topics: Disease Progression; Early Diagnosis; Humans; Plaque, Atherosclerotic; Positron Emission Tomography

2016
Evolving Role of Molecular Imaging with (18)F-Sodium Fluoride PET as a Biomarker for Calcium Metabolism.
    Current osteoporosis reports, 2016, Volume: 14, Issue:4

    Topics: Arthritis, Rheumatoid; Back Pain; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone and Bones

2016

Trials

14 trials available for sodium fluoride and Disease Exacerbation

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Exploring Spatial-Temporal Changes in
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 11-01, Volume: 38, Issue:31

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Bone Neoplasms; Disease Progression; Flu

2020
18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis.
    Circulation. Cardiovascular imaging, 2014, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Calcinosis; Disease Progression; Female;

2014
18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis.
    Circulation. Cardiovascular imaging, 2014, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Calcinosis; Disease Progression; Female;

2014
18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis.
    Circulation. Cardiovascular imaging, 2014, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Calcinosis; Disease Progression; Female;

2014
18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis.
    Circulation. Cardiovascular imaging, 2014, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Calcinosis; Disease Progression; Female;

2014
The effect of various model parameters on enamel caries lesions in a dose-response model in situ.
    Journal of dentistry, 2015, Volume: 43, Issue:10

    Topics: Adult; Animals; Cariostatic Agents; Cattle; Chlorhexidine; Cross-Over Studies; Dental Caries; Dental

2015
Frequency of Application of AmF/NaF/SnCl2 Solution and Its Potential in Controlling Human Enamel Erosion Progression: An in situ Study.
    Caries research, 2017, Volume: 51, Issue:2

    Topics: Adult; Cross-Over Studies; Disease Progression; Double-Blind Method; Fluorides, Topical; Humans; Mou

2017
In vitro efficacy of experimental tin- and fluoride-containing mouth rinses as anti-erosive agents in enamel.
    Journal of dentistry, 2009, Volume: 37, Issue:12

    Topics: Amines; Citric Acid; Dental Enamel; Diamines; Disease Progression; Drug Combinations; Fluorides; Hum

2009
Regression of post-orthodontic lesions by a remineralizing cream.
    Journal of dental research, 2009, Volume: 88, Issue:12

    Topics: Adolescent; Cariostatic Agents; Caseins; Child; Dental Caries; Disease Progression; Double-Blind Met

2009
Clinical effects of interdental cleansing on supragingival biofilm formation and development of experimental gingivitis.
    Oral health & preventive dentistry, 2009, Volume: 7, Issue:4

    Topics: Adult; Biofilms; Cariostatic Agents; Case-Control Studies; Dental Devices, Home Care; Dental Plaque;

2009
Randomized equivalence trial of intensive and semiannual applications of fluoride varnish in the primary dentition.
    Caries research, 2009, Volume: 43, Issue:6

    Topics: Cariostatic Agents; Child, Preschool; Cohort Studies; Dental Caries; Dental Caries Susceptibility; D

2009
Treatment of proximal superficial caries lesions on primary molar teeth with resin infiltration and fluoride varnish versus fluoride varnish only: efficacy after 1 year.
    Caries research, 2010, Volume: 44, Issue:1

    Topics: Acid Etching, Dental; Cariostatic Agents; Child; Child, Preschool; Cohort Studies; Composite Resins;

2010
Preventive effect of high-fluoride dentifrice (5,000 ppm) in caries-active adolescents: a 2-year clinical trial.
    Caries research, 2010, Volume: 44, Issue:3

    Topics: Adolescent; Age Factors; Dental Caries; Dentifrices; Disease Progression; DMF Index; Dose-Response R

2010
Comparison of the remineralizing potential of child formula dentifrices.
    International journal of paediatric dentistry, 2011, Volume: 21, Issue:2

    Topics: Cariostatic Agents; Chemistry, Pharmaceutical; Child; Dentifrices; Diamines; Disease Progression; Fl

2011
Low-fluoride dentifrice and caries lesion control in children with different caries experience: a randomized clinical trial.
    Caries research, 2008, Volume: 42, Issue:1

    Topics: Cariostatic Agents; Child, Preschool; Dental Caries; Dentifrices; Disease Progression; DMF Index; Do

2008
The use of a triclosan/copolymer dentifrice may retard the progression of periodontitis.
    Journal of clinical periodontology, 1997, Volume: 24, Issue:12

    Topics: Adult; Alveolar Bone Loss; Anti-Infective Agents, Local; Cariostatic Agents; Dental Plaque; Dentifri

1997

Other Studies

24 other studies available for sodium fluoride and Disease Exacerbation

ArticleYear
Bypass Grafting and Native Coronary Artery Disease Activity.
    JACC. Cardiovascular imaging, 2022, Volume: 15, Issue:5

    Topics: Aged; Calcinosis; Calcium; Coronary Angiography; Coronary Artery Disease; Disease Progression; Femal

2022
Aortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients.
    The international journal of cardiovascular imaging, 2020, Volume: 36, Issue:8

    Topics: Aged; Aortic Valve; Aortic Valve Stenosis; Asymptomatic Diseases; Calcinosis; Disease Progression; F

2020
Efficacy of bisphosphonates in detection of early enamel caries using NIR fluorescence imaging and inhibition of caries progression.
    International journal of medical sciences, 2021, Volume: 18, Issue:13

    Topics: Bone Density Conservation Agents; Contrast Media; Dental Caries; Dental Enamel; Diphosphonates; Dise

2021
The Impact of the Demineralized Organic Matrix on the Effect of TiF4 Varnish on the Progression of Dentin Erosive Loss.
    Caries research, 2017, Volume: 51, Issue:3

    Topics: Animals; Cariostatic Agents; Cattle; Citric Acid; Dentin; Disease Progression; Fluorides; Hydrogen-I

2017
Molecular Imaging of Vascular Calcification with
    International journal of molecular sciences, 2019, Mar-08, Volume: 20, Issue:5

    Topics: Aged; Coronary Artery Disease; Disease Progression; Female; Fluorine Radioisotopes; HIV; HIV Infecti

2019
The role of water and mineral-collagen interfacial bonding on microdamage progression in bone.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32, Issue:2

    Topics: Animals; Bone and Bones; Collagen; Compressive Strength; Disease Progression; Femur; Fluorocarbons;

2014
Erosion protection by calcium lactate/sodium fluoride rinses under different salivary flows in vitro.
    Caries research, 2014, Volume: 48, Issue:3

    Topics: Animals; Calcium Compounds; Cattle; Citric Acid; Dental Enamel; Dentin; Diffusion Chambers, Culture;

2014
The preventive effect of grape seed extract on artificial enamel caries progression in a microbial biofilm-induced caries model.
    Journal of dentistry, 2014, Volume: 42, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Cariostatic Agents; Cattle; Dental Caries; Dental Enamel;

2014
The effect of mouthwashes containing biguanides on the progression of erosion in dentin.
    BMC oral health, 2014, Oct-30, Volume: 14

    Topics: Animals; Anti-Infective Agents, Local; Biguanides; Cattle; Chlorhexidine; Citric Acid; Dentin; Disea

2014
The role of matrix metalloproteinases and cysteine-cathepsins on the progression of dentine erosion.
    Archives of oral biology, 2015, Volume: 60, Issue:9

    Topics: Cathepsins; Chlorhexidine; Cysteine; Dentin; Dipeptides; Disease Progression; Humans; In Vitro Techn

2015
(18)F-NaF PET Imaging of Early Coronary Artery Calcification.
    JACC. Cardiovascular imaging, 2016, Volume: 9, Issue:5

    Topics: Animals; Coronary Artery Disease; Coronary Vessels; Diet, Atherogenic; Disease Models, Animal; Disea

2016
Effect of sodium fluoride and stannous chloride associated with Nd:YAG laser irradiation on the progression of enamel erosion.
    Lasers in medical science, 2015, Volume: 30, Issue:9

    Topics: Animals; Cattle; Citric Acid; Dental Enamel; Disease Progression; Lasers, Solid-State; Sodium Fluori

2015
Valvular (18)F-Fluoride and (18)F-Fluorodeoxyglucose Uptake Predict Disease Progression and Clinical Outcome in Patients With Aortic Stenosis.
    Journal of the American College of Cardiology, 2015, Sep-08, Volume: 66, Issue:10

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Case-Control Studies; Disease Progress

2015
Erosion Prevention Potential of an Over-the-Counter Stabilized SnF2 Dentifrice Compared to 5000 ppm F Prescription-Strength Products.
    The Journal of clinical dentistry, 2015, Volume: 26, Issue:2

    Topics: Acidulated Phosphate Fluoride; Calcium Phosphates; Cariostatic Agents; Citric Acid; Dental Enamel; D

2015
Chronic Exposure to Bisphenol A Exacerbates Dental Fluorosis in Growing Rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016, Volume: 31, Issue:11

    Topics: Animals; Benzhydryl Compounds; Child; Dental Enamel; Disease Progression; Epithelium; Female; Fluoro

2016
Effect of stannous and fluoride concentration in a mouth rinse on erosive tissue loss in enamel in vitro.
    Archives of oral biology, 2009, Volume: 54, Issue:5

    Topics: Cariostatic Agents; Citric Acid; Dental Enamel; Diamines; Disease Progression; Fluorides; Humans; Hy

2009
Progress of oral sequelae during head-neck radiotherapy.
    The Chinese journal of dental research, 2010, Volume: 13, Issue:1

    Topics: Aged; Analysis of Variance; Cariostatic Agents; Cranial Irradiation; Dental Caries; Disease Progress

2010
Enamel protection: a comparison of marketed dentifrice performance against dental erosion.
    American journal of dentistry, 2011, Volume: 24, Issue:4

    Topics: Citric Acid; Dental Enamel; Dental Pellicle; Dentifrices; Disease Progression; Drug Combinations; Fl

2011
Effect of dentifrices against hydrochloric acid-induced erosion.
    Oral health & preventive dentistry, 2011, Volume: 9, Issue:3

    Topics: Animals; Cariostatic Agents; Cattle; Coloring Agents; Copper Sulfate; Dental Enamel; Dental Enamel P

2011
Noninvasive imaging in cardiovascular therapy: the promise of coronary arterial ¹⁸F-sodium fluoride uptake as a marker of plaque biology.
    Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:9

    Topics: Atherosclerosis; Biological Transport; Biomarkers; Coronary Artery Disease; Coronary Vessels; Diseas

2012
Submandibular gland aplasia and progressive dental caries: a case report.
    Australian dental journal, 2002, Volume: 47, Issue:4

    Topics: Adolescent; Cariostatic Agents; Dental Caries; Dental Enamel; Dental Restoration, Permanent; Disease

2002
Microradiography and confocal laser scanning microscopy applied to enamel lesions formed in vivo with and without fluoride varnish treatment.
    European journal of oral sciences, 1996, Volume: 104, Issue:4 ( Pt 1)

    Topics: Adolescent; Bicuspid; Chemical Precipitation; Child; Dental Caries; Dental Enamel; Disease Progressi

1996
Anticaries profile qualification of an improved whitening dentifrice.
    The Journal of clinical dentistry, 2001, Volume: 12, Issue:2

    Topics: Analysis of Variance; Cariostatic Agents; Dental Calculus; Dental Caries; Dental Enamel; Dentifrices

2001
Case reports. 1. Xerostomia.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1997, Volume: 18, Issue:2 Spec No

    Topics: Cariostatic Agents; Dentifrices; Disease Progression; Fluorides, Topical; Follow-Up Studies; Humans;

1997