sodium fluoride has been researched along with Breast Neoplasms in 26 studies
Breast Neoplasms: Tumors or cancer of the human BREAST.
Excerpt | Relevance | Reference |
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"The purpose of the study was to compare the diagnostic accuracy and relative usefulness of MRI and 18 F-NaF (sodium fluoride) PET/computed tomography (CT) for detection of spinal bone metastases in a cohort of patients with high-risk breast cancer (BrCa)." | 8.31 | Review of the role of MRI and 18 F-sodium fluoride PET/computed tomography in the characterisation of spinal bone metastases in a cohort of patients with breast cancer. ( Panagiotidis, E; Pant, V; Vinjamuri, S, 2023) |
"18F- Sodium Fluoride (NaF) is an excellent bone imaging agent used for skeletal staging but can also be localized in extra osseous calcifying lesions." | 5.56 | Incidental brain metastasis of breast cancer detected on 18F-Sodium Fluoride (NaF) PET-CT. ( Ahmed, N; Kandari, FA; Muzaffar, S; Usmani, S, 2020) |
"A 73-year-old woman with breast cancer presented for restaging FDG PET/CT, which showed intense activity throughout almost the entire axial skeleton and no osseous metastases." | 5.39 | 18F sodium fluoride PET/CT detects osseous metastases from breast cancer missed on FDG PET/CT with marrow rebound. ( Avery, R; Kuo, PH, 2013) |
"In a national prospective registry, we previously studied the impact of (18)F-sodium fluoride PET (NaF PET) on the intended management of cancer patients with osseous metastases." | 5.20 | 18F-fluoride PET used for treatment monitoring of systemic cancer therapy: results from the National Oncologic PET Registry. ( Duan, F; Hanna, L; Hillner, BE; Quinn, B; Shields, AF; Siegel, BA, 2015) |
"The purpose of the study was to compare the diagnostic accuracy and relative usefulness of MRI and 18 F-NaF (sodium fluoride) PET/computed tomography (CT) for detection of spinal bone metastases in a cohort of patients with high-risk breast cancer (BrCa)." | 4.31 | Review of the role of MRI and 18 F-sodium fluoride PET/computed tomography in the characterisation of spinal bone metastases in a cohort of patients with breast cancer. ( Panagiotidis, E; Pant, V; Vinjamuri, S, 2023) |
"Unexpectedly, breast cancer also revealed increased NaF activity." | 1.56 | 18F-NaF Uptake in Breast Cancer. ( Chen, Y; Fu, W; Liu, H; Liu, L, 2020) |
"18F- Sodium Fluoride (NaF) is an excellent bone imaging agent used for skeletal staging but can also be localized in extra osseous calcifying lesions." | 1.56 | Incidental brain metastasis of breast cancer detected on 18F-Sodium Fluoride (NaF) PET-CT. ( Ahmed, N; Kandari, FA; Muzaffar, S; Usmani, S, 2020) |
"Patients with breast cancer, referred for F-NaF PET/CT between February 2014 and June 2016, were included in a database." | 1.48 | Accuracy of 18F-NaF PET/CT in bone metastasis detection and its effect on patient management in patients with breast carcinoma. ( Broos, WAM; Knol, RJJ; van der Zant, FM; Wondergem, M, 2018) |
"In 10 patients with breast cancer, skeletal tumour burden in pretreatment and post-treatment F-NaF PET/CT was compared with tumour marker and clinical evolution." | 1.46 | Assessment of skeletal tumour burden on 18F-NaF PET/CT using a new quantitative method. ( Costa, G; Iagaru, A; Lapa, P; Marques, M; Pedroso de Lima, J, 2017) |
"Thirty patients (15 women with breast cancer and 15 men with prostate cancer) referred for standard-of-care bone scintigraphy were prospectively enrolled in this study." | 1.42 | Prospective Comparison of 99mTc-MDP Scintigraphy, Combined 18F-NaF and 18F-FDG PET/CT, and Whole-Body MRI in Patients with Breast and Prostate Cancer. ( Barkhodari, A; Gambhir, SS; Iagaru, A; Jackson, T; Jamali, M; Loening, A; Minamimoto, R; Mosci, C; Obara, P; Taviani, V; Vasanawala, S, 2015) |
"A 43-year-old woman with breast cancer underwent Tc-hydroxymethylene diphosphonate bone scintigraphy for preoperative workup." | 1.42 | 18F-NaF PET/CT Findings in Fibrous Dysplasia. ( Lee, H; Lee, KS; Lee, WW, 2015) |
"Type I microcalcifications are associated mainly with benign tumors, whereas type II microcalcifications are produced internally by malignant cells." | 1.40 | An Approach to Breast Cancer Diagnosis via PET Imaging of Microcalcifications Using (18)F-NaF. ( Abramson, V; Barnes, S; Gore, JC; Mahadevan-Jansen, A; McIntyre, JO; Ngyuen, TQ; Peterson, TE; Sanders, M; Shokouhi, S; Tantawy, MN; True, JM; Wilson, GH; Yankeelov, TE, 2014) |
"A 73-year-old woman with breast cancer presented for restaging FDG PET/CT, which showed intense activity throughout almost the entire axial skeleton and no osseous metastases." | 1.39 | 18F sodium fluoride PET/CT detects osseous metastases from breast cancer missed on FDG PET/CT with marrow rebound. ( Avery, R; Kuo, PH, 2013) |
"Slices of more than 200 breast tumors were used." | 1.33 | A new method to assess drug sensitivity on breast tumor acute slices preparation. ( Kob, A; Mestres, P; Morguet, A; Schmidt, W; Thedinga, E, 2006) |
"In the human breast carcinoma cell line MDA-468 addition of epidermal growth factor (EGF) is growth inhibitory." | 1.28 | A novel calcium signalling response in the breast cancer cell line MDA-468. ( Kremer, S; Margolis, B; Skorecki, K, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (11.54) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (7.69) | 29.6817 |
2010's | 14 (53.85) | 24.3611 |
2020's | 7 (26.92) | 2.80 |
Authors | Studies |
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Bénard, F | 1 |
Harsini, S | 1 |
Wilson, D | 1 |
Zukotynski, K | 1 |
Abikhzer, G | 2 |
Turcotte, E | 1 |
Cossette, M | 1 |
Metser, U | 1 |
Romsa, J | 1 |
Martin, M | 1 |
Mar, C | 1 |
Saad, F | 1 |
Soucy, JP | 1 |
Eigl, BJ | 1 |
Black, P | 1 |
Krauze, A | 1 |
Burrell, S | 1 |
Nichol, A | 1 |
Tardif, JC | 1 |
Panagiotidis, E | 1 |
Pant, V | 1 |
Vinjamuri, S | 1 |
Sinha, P | 1 |
Lamonica, DM | 1 |
Liu, H | 2 |
Liu, L | 3 |
Fu, W | 1 |
Chen, Y | 5 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 4 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Song, J | 3 |
Bascuñán, J | 2 |
Chu, Y | 1 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Li, X | 10 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
Alias, A | 1 |
Zakaria, Y | 1 |
Abu-Bakar, N | 1 |
Naveed, A | 1 |
Jilani, K | 1 |
Siddique, AB | 1 |
Akbar, M | 1 |
Riaz, M | 1 |
Mushtaq, Z | 1 |
Sikandar, M | 1 |
Ilyas, S | 1 |
Bibi, I | 1 |
Asghar, A | 1 |
Rasool, G | 1 |
Irfan, M | 1 |
Li, XY | 1 |
Zhao, S | 1 |
Fan, XH | 1 |
Chen, KP | 1 |
Hua, W | 1 |
Liu, ZM | 1 |
Xue, XD | 1 |
Zhou, B | 1 |
Zhang, S | 2 |
Xing, YL | 1 |
Chen, MA | 1 |
Sun, Y | 1 |
Neradilek, MB | 1 |
Wu, XT | 1 |
Zhang, D | 2 |
Huang, W | 1 |
Cui, Y | 1 |
Yang, QQ | 1 |
Li, HW | 1 |
Zhao, XQ | 1 |
Hossein Rashidi, B | 1 |
Tarafdari, A | 1 |
Ghazimirsaeed, ST | 1 |
Shahrokh Tehraninezhad, E | 1 |
Keikha, F | 1 |
Eslami, B | 1 |
Ghazimirsaeed, SM | 1 |
Jafarabadi, M | 1 |
Silvani, Y | 1 |
Lovita, AND | 1 |
Maharani, A | 1 |
Wiyasa, IWA | 1 |
Sujuti, H | 1 |
Ratnawati, R | 1 |
Raras, TYM | 1 |
Lemin, AS | 1 |
Rahman, MM | 1 |
Pangarah, CA | 1 |
Kiyu, A | 1 |
Zeng, C | 2 |
Du, H | 1 |
Lin, D | 1 |
Jalan, D | 1 |
Rubagumya, F | 1 |
Hopman, WM | 1 |
Vanderpuye, V | 1 |
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Okunade, KS | 1 |
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Rabiu, KA | 1 |
Anorlu, RI | 1 |
Xu, C | 2 |
Xiang, Y | 1 |
Xu, X | 1 |
Zhou, L | 2 |
Dong, X | 1 |
Tang, S | 1 |
Gao, XC | 1 |
Wei, CH | 1 |
Zhang, RG | 1 |
Cai, Q | 1 |
He, Y | 1 |
Tong, F | 1 |
Dong, JH | 1 |
Wu, G | 1 |
Dong, XR | 1 |
Tang, X | 1 |
Tao, F | 1 |
Xiang, W | 1 |
Zhao, Y | 2 |
Jin, L | 1 |
Tao, H | 1 |
Lei, Y | 1 |
Gan, H | 1 |
Huang, Y | 1 |
Chen, L | 4 |
Shan, A | 1 |
Zhao, H | 2 |
Wu, M | 2 |
Ma, Q | 1 |
Wang, J | 4 |
Zhang, E | 1 |
Zhang, J | 3 |
Li, Y | 5 |
Xue, F | 1 |
Deng, L | 1 |
Yan, Z | 2 |
Wang, Y | 2 |
Meng, J | 1 |
Chen, G | 2 |
Anastassiadou, M | 1 |
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Carrasco Cabrera, L | 1 |
Greco, L | 1 |
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Theobald, A | 1 |
Vagenende, B | 1 |
Verani, A | 1 |
Du, L | 1 |
Liu, X | 1 |
Ren, Y | 1 |
Li, J | 7 |
Li, P | 1 |
Jiao, Q | 1 |
Meng, P | 1 |
Wang, F | 2 |
Wang, YS | 1 |
Wang, C | 3 |
Zhou, X | 2 |
Wang, W | 1 |
Wang, S | 2 |
Hou, J | 1 |
Zhang, A | 1 |
Lv, B | 1 |
Gao, C | 1 |
Pang, D | 1 |
Lu, K | 1 |
Ahmad, NH | 1 |
Wang, L | 1 |
Zhu, J | 2 |
Zhang, L | 2 |
Zhuang, T | 1 |
Tu, J | 1 |
Zhao, Z | 1 |
Qu, Y | 1 |
Yao, H | 1 |
Wang, X | 5 |
Lee, DF | 1 |
Shen, J | 3 |
Wen, L | 1 |
Huang, G | 2 |
Xie, X | 1 |
Zhao, Q | 1 |
Hu, W | 1 |
Zhang, Y | 4 |
Wu, X | 1 |
Lu, J | 2 |
Li, M | 1 |
Li, W | 2 |
Wu, W | 1 |
Du, F | 1 |
Ji, H | 1 |
Yang, X | 2 |
Xu, Z | 1 |
Wan, L | 1 |
Wen, Q | 1 |
Cho, CH | 1 |
Zou, C | 1 |
Xiao, Z | 1 |
Liao, J | 1 |
Su, X | 1 |
Bi, Z | 1 |
Su, Q | 1 |
Huang, H | 2 |
Wei, Y | 2 |
Gao, Y | 2 |
Na, KJ | 1 |
Choi, H | 1 |
Oh, HR | 1 |
Kim, YH | 1 |
Lee, SB | 1 |
Jung, YJ | 1 |
Koh, J | 1 |
Park, S | 1 |
Lee, HJ | 1 |
Jeon, YK | 1 |
Chung, DH | 1 |
Paeng, JC | 1 |
Park, IK | 1 |
Kang, CH | 1 |
Cheon, GJ | 1 |
Kang, KW | 1 |
Lee, DS | 1 |
Kim, YT | 1 |
Pajuelo-Lozano, N | 1 |
Alcalá, S | 1 |
Sainz, B | 1 |
Perona, R | 1 |
Sanchez-Perez, I | 1 |
Logotheti, S | 1 |
Marquardt, S | 1 |
Gupta, SK | 1 |
Richter, C | 1 |
Edelhäuser, BAH | 1 |
Engelmann, D | 1 |
Brenmoehl, J | 1 |
Söhnchen, C | 1 |
Murr, N | 1 |
Alpers, M | 1 |
Singh, KP | 1 |
Wolkenhauer, O | 1 |
Heckl, D | 1 |
Spitschak, A | 1 |
Pützer, BM | 1 |
Liao, Y | 1 |
Cheng, J | 1 |
Kong, X | 1 |
Li, S | 1 |
Zhang, M | 4 |
Zhang, H | 1 |
Yang, T | 2 |
Dong, Y | 1 |
Xu, Y | 1 |
Yuan, Z | 1 |
Cao, J | 1 |
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Luo, Z | 1 |
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Yao, Y | 1 |
Liu, Z | 2 |
Liang, C | 1 |
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Huang, Z | 2 |
Qian, J | 1 |
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Hu, J | 2 |
Wang, H | 2 |
Liu, Y | 4 |
Mi, Y | 1 |
Kong, H | 1 |
Xi, D | 1 |
Yan, W | 1 |
Luo, X | 1 |
Ning, Q | 1 |
Chang, X | 2 |
Zhang, T | 2 |
Wang, Q | 2 |
Rathore, MG | 1 |
Reddy, K | 1 |
Chen, H | 1 |
Shin, SH | 1 |
Ma, WY | 1 |
Bode, AM | 1 |
Dong, Z | 1 |
Mu, W | 1 |
Liu, C | 3 |
Gao, F | 1 |
Qi, Y | 1 |
Lu, H | 1 |
Zhang, X | 4 |
Cai, X | 1 |
Ji, RY | 1 |
Hou, Y | 3 |
Tian, J | 2 |
Shi, Y | 1 |
Ying, S | 1 |
Tan, M | 1 |
Feng, G | 1 |
Kuang, Y | 1 |
Chen, D | 1 |
Wu, D | 3 |
Zhu, ZQ | 1 |
Tang, HX | 1 |
Shi, ZE | 1 |
Kang, J | 1 |
Liu, Q | 1 |
Qi, J | 2 |
Mu, J | 1 |
Cong, Z | 1 |
Chen, S | 2 |
Fu, D | 1 |
Li, Z | 2 |
Celestrin, CP | 1 |
Rocha, GZ | 1 |
Stein, AM | 1 |
Guadagnini, D | 1 |
Tadelle, RM | 1 |
Saad, MJA | 1 |
Oliveira, AG | 1 |
Bianconi, V | 1 |
Bronzo, P | 1 |
Banach, M | 1 |
Sahebkar, A | 1 |
Mannarino, MR | 1 |
Pirro, M | 1 |
Patsourakos, NG | 1 |
Kouvari, M | 1 |
Kotidis, A | 1 |
Kalantzi, KI | 1 |
Tsoumani, ME | 1 |
Anastasiadis, F | 1 |
Andronikos, P | 1 |
Aslanidou, T | 1 |
Efraimidis, P | 1 |
Georgiopoulos, A | 1 |
Gerakiou, K | 1 |
Grigoriadou-Skouta, E | 1 |
Grigoropoulos, P | 1 |
Hatzopoulos, D | 1 |
Kartalis, A | 1 |
Lyras, A | 1 |
Markatos, G | 1 |
Mikrogeorgiou, A | 1 |
Myroforou, I | 1 |
Orkopoulos, A | 1 |
Pavlidis, P | 1 |
Petras, C | 1 |
Riga, M | 1 |
Skouloudi, M | 1 |
Smyrnioudis, N | 1 |
Thomaidis, K | 1 |
Tsikouri, GE | 1 |
Tsikouris, EI | 1 |
Zisimos, K | 1 |
Vavoulis, P | 1 |
Vitali, MG | 1 |
Vitsas, G | 1 |
Vogiatzidis, C | 1 |
Chantanis, S | 1 |
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Panagiotakos, DB | 1 |
Tselepis, AD | 1 |
Jungen, C | 1 |
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Eickholt, C | 1 |
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Kuklik, P | 1 |
Klatt, N | 1 |
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Akbulak, RO | 1 |
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Szczepanik, M | 1 |
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Grytczuk, M | 1 |
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Wójciak, R | 1 |
Walkowiak, J | 1 |
Lu, Y | 1 |
Xi, J | 1 |
Li, C | 1 |
Chen, W | 2 |
Hu, X | 1 |
Zhang, F | 1 |
Wei, H | 1 |
Wang, Z | 1 |
Gurzu, S | 1 |
Jung, I | 1 |
Sugimura, H | 2 |
Stefan-van Staden, RI | 1 |
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Iwashita, Y | 1 |
Szodorai, R | 1 |
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Culquichicón, C | 1 |
Solis Condor, R | 1 |
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Sebayang, SK | 1 |
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Kuswanto, H | 1 |
Foroutan, T | 1 |
Ahmadi, F | 1 |
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Khalvati, S | 1 |
Zhang, Q | 2 |
Lyu, Y | 1 |
Huang, J | 1 |
Yu, N | 1 |
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Hou, H | 1 |
Zhao, T | 1 |
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Govindasamy, V | 1 |
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Dhakate, SR | 1 |
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Chandgude, AL | 1 |
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Valle, J | 1 |
Flores, K | 1 |
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Valdes, C | 1 |
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Padilla, V | 1 |
Alcoutlabi, M | 1 |
Parsons, J | 1 |
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Hamed, M | 1 |
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Thevenot, P | 1 |
Cohen, A | 1 |
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Menezes, AMB | 1 |
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Perez-Padilla, R | 1 |
Jarvis, D | 1 |
de Oliveira, PD | 1 |
Wehrmeister, FC | 1 |
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Wong, J | 1 |
Ryan, CM | 1 |
Bellingham, G | 1 |
Singh, M | 2 |
Waseem, R | 1 |
Eckert, DJ | 1 |
Chung, F | 1 |
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Shimpi, N | 1 |
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Glurich, I | 1 |
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Buxton, R | 1 |
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Ploutz-Snyder, R | 1 |
Guilliams, M | 1 |
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Ploutz-Snyder, LL | 1 |
Martens, C | 1 |
Goplen, FK | 1 |
Aasen, T | 1 |
Gjestad, R | 1 |
Nordfalk, KF | 1 |
Nordahl, SHG | 1 |
Inoue, T | 1 |
Soshi, S | 1 |
Kubota, M | 1 |
Marumo, K | 1 |
Mortensen, NP | 1 |
Caffaro, MM | 1 |
Patel, PR | 2 |
Uddin, MJ | 1 |
Aravamudhan, S | 1 |
Sumner, SJ | 1 |
Fennell, TR | 1 |
Gal, RL | 1 |
Cohen, NJ | 1 |
Kruger, D | 1 |
Beck, RW | 1 |
Bergenstal, RM | 1 |
Calhoun, P | 1 |
Cushman, T | 1 |
Haban, A | 1 |
Hood, K | 1 |
Johnson, ML | 1 |
McArthur, T | 1 |
Olson, BA | 1 |
Weinstock, RS | 1 |
Oser, SM | 1 |
Oser, TK | 1 |
Bugielski, B | 1 |
Strayer, H | 1 |
Aleppo, G | 1 |
Maruyama, H | 1 |
Hirayama, K | 1 |
Yamashita, M | 1 |
Ohgi, K | 1 |
Tsujimoto, R | 1 |
Takayasu, M | 1 |
Shimohata, H | 1 |
Kobayashi, M | 1 |
Buscagan, TM | 1 |
Rees, DC | 1 |
Jaborek, JR | 1 |
Zerby, HN | 1 |
Wick, MP | 1 |
Fluharty, FL | 1 |
Moeller, SJ | 1 |
Razavi, P | 1 |
Dickler, MN | 1 |
Shah, PD | 1 |
Toy, W | 1 |
Brown, DN | 1 |
Won, HH | 1 |
Li, BT | 1 |
Shen, R | 1 |
Vasan, N | 1 |
Modi, S | 1 |
Jhaveri, K | 1 |
Caravella, BA | 1 |
Patil, S | 1 |
Selenica, P | 1 |
Zamora, S | 1 |
Cowan, AM | 1 |
Comen, E | 1 |
Singh, A | 1 |
Covey, A | 1 |
Berger, MF | 1 |
Hudis, CA | 1 |
Norton, L | 1 |
Nagy, RJ | 1 |
Odegaard, JI | 1 |
Lanman, RB | 1 |
Solit, DB | 1 |
Robson, ME | 1 |
Lacouture, ME | 1 |
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Reis-Filho, JS | 1 |
Moynahan, ME | 1 |
Scaltriti, M | 1 |
Chandarlapaty, S | 1 |
Papouskova, K | 1 |
Moravcova, M | 1 |
Masrati, G | 1 |
Ben-Tal, N | 1 |
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Zimmermannova, O | 1 |
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Fan, Y | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
18F- Sodium Fluoride PET Imaging as a Replacement for Bone Scintigraphy[NCT01930812] | Phase 3 | 286 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
The National Oncologic PET Registry[NCT00868582] | 333,000 participants (Anticipated) | Observational | 2006-05-31 | Active, not recruiting | |||
Combined 18F-NaF/18F-FDG PET/MRI for Detection of Skeletal Metastases[NCT00375830] | Phase 2 | 114 participants (Actual) | Interventional | 2006-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Participants in Cohort 3 received 99mTc-methylene diphosphonate (MDP) whole-body bone scintigraphy (WBBS) and 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / magnetic imaging resonance (PET/MRI) scans. On the basis of the scans, participants with skeletal lesions were identified. The outcome is reported as the number of Cohort 3 participants for whom skeletal lesions were identified by each scan methodology, a number without dispersion. (NCT00375830)
Timeframe: 30 days
Intervention | Participants (Count of Participants) |
---|---|
Cohort 3 - 99mTc-methyl Diphosphonate (MDP) Bone Scan | 37 |
Cohort 3 - 18F-NaF / 18F-FDG PET/MRI | 45 |
Participants in Cohort 3 received 99mTc-methylene diphosphonate (MDP) whole-body bone scintigraphy (WBBS) and 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / magnetic imaging resonance (PET/MRI) scans. On the basis of the scans, the total number skeletal lesions identified in the participants was determined. The outcome is reported as the total number skeletal lesions identified by each scan methodology, a number without dispersion. (NCT00375830)
Timeframe: 30 days
Intervention | lesions (Number) |
---|---|
Cohort 3 - 99mTc-methyl Diphosphonate (MDP) Bone Scan | 81 |
Cohort 3 - 18F-NaF / 18F-FDG PET/MRI | 140 |
The medical value of 18F-sodium fluoride (NaF) positron emission tomography / computed tomography (PET/CT) vs 18F-fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) was assessed on the basis of the radiation oncologist's medical assessment of image quality and detected extent of disease, for each participant diagnosed with osseous (skeletal) metastases. Per protocol, the data were collected and the outcome is reported for Cohort 1 only. The outcome is reported as the number of participants for whom the medical value of the image was superior for 18-NaF PET/CT compared to 18F-FDG PET/CT, the same between both scans, or inferior for 18-NaF PET/CT compared to 18F-FDG PET/CT. The outcome result is represented as a number without dispersion. (NCT00375830)
Timeframe: 30 days
Intervention | Participants (Count of Participants) | ||
---|---|---|---|
18F-NaF > 18F-FDG | 18F-NaF = 18F-FDG | 18F-NaF < 18F-FDG | |
Cohort 1 Pilot-WB-MRI & Combined 18F-NaF-CT/18F-FDG-PET Scans | 3 | 0 | 0 |
"The medical value of 18F-sodium fluoride (NaF) positron emission tomography / computed tomography (PET/CT) vs 99mTc-methylene diphosphonate (MDP) bone scintigraphy was assessed on the basis of the radiation oncologist's medical assessment of image quality and detected extent of disease, for each participant. Per protocol, the data were collected and the outcome is reported for Cohort 1 only. The outcome is reported as the number of participants for whom the medical value of the image was superior for 18F-NaF vs 99mTc-MDP bone scintigraphy (18F-NaF > 99mTc-MDP), the same between both scans (18F-NaF = 99mTc-MDP), or inferior for 18F-NaF vs 99mTc-MDP bone scintigraphy (18F-NaF < 99mTc-MDP)." (NCT00375830)
Timeframe: 30 days
Intervention | Participants (Count of Participants) | ||
---|---|---|---|
18F-NaF > 99mTc-MDP | 18F-NaF = 99mTc-MDP | 18F-NaF < 99mTc-MDP | |
Cohort 1 Pilot-WB-MRI & Combined 18F-NaF-CT/18F-FDG-PET Scans | 10 | 0 | 0 |
"Sensitivity; positive predictive value (PPV); and accuracy for the detection of extraskeletal lesions was assessed for 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) and for whole body magnetic imaging resonance (WB-MRI).~Sensitivity is a percentage that defines the proportion of true positive participants with the disease in a total group of participants.~PPV is the probability that participants with a positive screening test truly have the disease.~Accuracy is the proportion of true results (both true positives and true negatives) among the total number of cases examined.~Per protocol, the data were collected and the outcome is reported for Cohort 2 only. Sensitivity, PPV, and accuracy are reported as a percentage, a number without dispersion. Higher numbers represent better detection." (NCT00375830)
Timeframe: 30 days
Intervention | percentage of particpants (Number) | ||
---|---|---|---|
Sensitivity | Positive predictive value | Accuracy | |
Cohort 2 - Combined 18F-NaF-CT/18F-FDG-PET Scan | 92.9 | 81.3 | 76.5 |
Cohort 2 - Whole Body-MRI Scan | 92.9 | 86.7 | 82.4 |
Sensitivity and accuracy for the detection of skeletal lesions was assessed for 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) and for 99mTc-methylene diphosphonate (MDP) bone scintigraphy. Per protocol, the data were collected and the outcome is reported for Cohort 2 only. Sensitivity and accuracy are reported as a percentage, a number without dispersion. Higher numbers represent better detection. (NCT00375830)
Timeframe: 30 days
Intervention | percentage of participants (Number) | |
---|---|---|
Sensitivity | Accuracy | |
Cohort 2 - 99mTc-MDP Bone Scintigraphy Scan | 64.6 | 65.9 |
Cohort 2 Combined 18F-NaF-CT/18F-FDG-PET Scan | 96.2 | 89.8 |
Sensitivity and accuracy for the detection of skeletal lesions was assessed for 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) and for whole body magnetic imaging resonance (WB-MRI). Per protocol, the data were collected and the outcome is reported for Cohort 2 only. Sensitivity and accuracy are reported as a percentage, a number without dispersion. Higher numbers represent better detection. (NCT00375830)
Timeframe: 30 days
Intervention | percentage of particpants (Number) | |
---|---|---|
Sensitivity | Accuracy | |
Cohort 2 - Combined 18F-NaF-CT/18F-FDG-PET Scan | 96.2 | 89.8 |
Cohort 2 - WB-MRI Scan | 81.4 | 74.7 |
Overall sensitivity and accuracy for the detection of tumor lesions was assessed for 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) and for whole body magnetic imaging resonance (WB-MRI). Per protocol, the data were collected and the outcome is reported for Cohort 2 only. Sensitivity and accuracy are reported as a percentage, a number without dispersion. Higher numbers represent better detection. (NCT00375830)
Timeframe: 30 days
Intervention | percentage of participants (Number) | |
---|---|---|
Sensitivity | Accuracy | |
Cohort 2 - Combined 18F-NaF-CT/18F-FDG-PET Scan | 95.7 | 87.6 |
Cohort 2 - Whole Body Magnetic Resonance Imaging (WB-MRI) Scan | 83.3 | 76.0 |
Overall sensitivity and accuracy for the detection of tumor lesions was assessed for 18F-sodium fluoride (NaF) / 18F-fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) and for 99mTc-methylene diphosphonate (MDP) bone scintigraphy. Per protocol, the data were collected and the outcome is reported for Cohort 2 only. Sensitivity and accuracy are reported as a percentage, a number without dispersion. Higher numbers represent better detection. (NCT00375830)
Timeframe: 30 days
Intervention | percentage of participants (Number) | |
---|---|---|
Sensitivity | Accuracy | |
Cohort 2 Combined 18F-NaF-CT/18F-FDG-PET Scan | 95.7 | 87.6 |
Cohort 2 WB-MRI & 99mTc-MDP Bone Scintigraphy | 91.6 | 83.0 |
4 reviews available for sodium fluoride and Breast Neoplasms
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
[State of the art in nuclear imaging for the diagnosis of bone metastases].
Topics: Bone Neoplasms; Breast Neoplasms; Female; Fluorodeoxyglucose F18; Humans; Kidney Neoplasms; Lung Neo | 2013 |
[PET/CT in breast cancer: an update].
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Dideoxynucleosides; Estradiol; Female; Fluorodeoxygluco | 2009 |
Diagnosis of bone disease by core biopsies.
Topics: Adult; Aged; Biopsy; Bone and Bones; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Female; Humans | 1981 |
4 trials available for sodium fluoride and Breast Neoplasms
Article | Year |
---|---|
Intra-individual comparison of
Topics: Bone Neoplasms; Breast Neoplasms; Canada; Fluorodeoxyglucose F18; Humans; Male; Multimodal Imaging; | 2022 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
18F-fluoride PET used for treatment monitoring of systemic cancer therapy: results from the National Oncologic PET Registry.
Topics: Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Databases, Factual; Female; Fluorodeoxygl | 2015 |
Incremental Value of Cocktail 18F-FDG and 18F-NaF PET/CT Over 18F-FDG PET/CT Alone for Characterization of Skeletal Metastases in Breast Cancer.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F1 | 2017 |
19 other studies available for sodium fluoride and Breast Neoplasms
Article | Year |
---|---|
Review of the role of MRI and 18 F-sodium fluoride PET/computed tomography in the characterisation of spinal bone metastases in a cohort of patients with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Hu | 2023 |
Beyond the
Topics: Breast Neoplasms; Humans; Male; Positron Emission Tomography Computed Tomography; Prostatic Neoplasm | 2023 |
18F-NaF Uptake in Breast Cancer.
Topics: Biological Transport; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Humans; Midd | 2020 |
Rare Thyroid Cartilage Metastasis From Breast Cancer Visualized on 18F-NaF PET/CT.
Topics: Aged; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Humans; Laryngeal Neoplasms; | 2021 |
Incidental brain metastasis of breast cancer detected on 18F-Sodium Fluoride (NaF) PET-CT.
Topics: Adult; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Humans; Po | 2020 |
Accuracy of 18F-NaF PET/CT in bone metastasis detection and its effect on patient management in patients with breast carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Fo | 2018 |
Breast Tumor Microcalcification Induced by Bone Morphogenetic Protein-2: A New Murine Model for Human Breast Tumor Diagnosis.
Topics: Animals; Bone Morphogenetic Protein 2; Breast Neoplasms; Calcinosis; Cell Line; Female; Fluorine Rad | 2018 |
18F sodium fluoride PET/CT detects osseous metastases from breast cancer missed on FDG PET/CT with marrow rebound.
Topics: Aged; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Huma | 2013 |
An Approach to Breast Cancer Diagnosis via PET Imaging of Microcalcifications Using (18)F-NaF.
Topics: Animals; Breast Neoplasms; Calcinosis; Cell Line, Tumor; Durapatite; Female; Fluorine Radioisotopes; | 2014 |
Added value of using a cocktail of F-18 sodium fluoride and F-18 fluorodeoxyglucose in positron emission tomography/computed tomography for detecting bony metastasis: a case report.
Topics: Bone Neoplasms; Breast Neoplasms; Female; Fluorodeoxyglucose F18; Humans; Middle Aged; Multimodal Im | 2015 |
18F-FDG PET/CT is a prognostic biomarker in patients affected by bone metastases from breast cancer in comparison with 18F-NaF PET/CT.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Neoplasms; Breast Neoplasms; Female; Fluorodeoxyglu | 2015 |
Prospective Comparison of 99mTc-MDP Scintigraphy, Combined 18F-NaF and 18F-FDG PET/CT, and Whole-Body MRI in Patients with Breast and Prostate Cancer.
Topics: Adult; Aged; Bone and Bones; Breast Neoplasms; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F1 | 2015 |
18F-NaF PET/CT Findings in Fibrous Dysplasia.
Topics: Adult; Breast Neoplasms; Diagnosis, Differential; Female; Fibrous Dysplasia of Bone; Fluorine Radioi | 2015 |
Intense 99mTc-MDP and 18F-NaF Activity in Long-standing Subcutaneous Implants.
Topics: Breast Implants; Breast Neoplasms; Female; Fluorodeoxyglucose F18; Humans; Middle Aged; Positron Emi | 2016 |
Prospective comparison of whole-body bone SPECT and sodium 18F-fluoride PET in the detection of bone metastases from breast cancer.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radioisotopes; Humans; Middle Aged; | 2016 |
Assessment of skeletal tumour burden on 18F-NaF PET/CT using a new quantitative method.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Neoplasms; Breast Neoplasms; Female; Fluorine Radio | 2017 |
EFFECT OF SODIUM FLUORIDE ON TUMOR GROWTH.
Topics: Animals; Breast Neoplasms; Bromides; Carcinogens; Fluorides; Humans; Mammary Neoplasms, Animal; Mamm | 1965 |
A new method to assess drug sensitivity on breast tumor acute slices preparation.
Topics: Breast Neoplasms; Diffusion Chambers, Culture; Drug Resistance, Neoplasm; Drug Screening Assays, Ant | 2006 |
A novel calcium signalling response in the breast cancer cell line MDA-468.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Breast Neoplasms; Calcium; Cell Line; Chlorides; Ep | 1989 |