sodium fluoride has been researched along with Abnormalities, Autosome in 25 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The US National Toxicology Program has shown equivocal evidence of carcinogenic activity of sodium fluoride (NaF) in male F344/N rats based on the occurrence of five osteosarcomas in treated animals." | 3.69 | Clastogenic activity of sodium fluoride to rat vertebral body-derived cells in culture. ( Mihashi, M; Tsutsui, T, 1996) |
| " The present study was intended to determine whether the fluoride (F)-induced genotoxicity could be reduced by substituting high F-containing water after 30 days with safe drinking water, containing 0." | 1.37 | Reduction in fluoride-induced genotoxicity in mouse bone marrow cells after substituting high fluoride-containing water with safe drinking water. ( Bhattacharya, S; Chattopadhyay, A; Podder, S, 2011) |
| " Results revealed that curcumin efficiently ameliorates the toxic effect of As and F by reducing the frequency of structural aberrations (>60%), hypoploidy (>50%) and primary DNA damage." | 1.36 | Curcumin supplementation protects from genotoxic effects of arsenic and fluoride. ( Rao, MV; Tiwari, H, 2010) |
| "No increase in the frequency of chromosome aberrations was elicited in cultures treated for 1-3 weeks with NaF over the range of doses examined." | 1.29 | No increases in chromosome aberrations in human diploid fibroblasts following exposure to low concentrations of sodium fluoride for long times. ( Hamaguchi, F; Matsudo, Y; Someya, T; Takahashi, M; Tanaka, Y; Tsutsui, T; Uehama, A; Yamamoto, H, 1995) |
| "NaF is known to induce chromosome aberrations at these concentrations in human cells, but not in most rodent cells." | 1.29 | Clastogenic activity of sodium fluoride in great ape cells. ( Ishida, T; Kishi, K, 1993) |
| "Inducibility of chromosome aberrations of the cells following treatment with NaF was also dependent upon the phase of the cell cycle." | 1.29 | Cell cycle dependence of cytotoxicity and clastogenicity induced by treatment of synchronized human diploid fibroblasts with sodium fluoride. ( Hayashi, N; Tsutsui, T, 1993) |
| "Inducibility of chromosome aberrations of the cells following treatment with sodium fluoride was also dependent upon the phase of cell cycle." | 1.28 | [Dependence of lethality and incidence of chromosome aberrations induced by treatment of synchronized human diploid fibroblasts with sodium fluoride on different periods of the cell cycle]. ( Suzuki, N; Tsutsui, T, 1989) |
| "Furthermore, a significant increase in chromosome aberrations at the chromatid level, sister chromatid exchanges, and unscheduled DNA synthesis was induced by NaF in a dose- and time-dependent manner." | 1.27 | Sodium fluoride-induced morphological and neoplastic transformation, chromosome aberrations, sister chromatid exchanges, and unscheduled DNA synthesis in cultured syrian hamster embryo cells. ( Ohmori, M; Suzuki, N; Tsutsui, T, 1984) |
| "Sodium fluoride (NaF) has previously been shown to be clastogenic in vitro in Syrian hamster cells and human fibroblasts." | 1.27 | Extrapolation from in vitro tests to human risk: experience with sodium fluoride clastogenicity. ( Roberts, SA; Scott, D, 1987) |
| " However, the incidence of micronucleated polychromatic erythrocytes in male AP rats dosed 1000 mg/kg NaF (the maximum tolerated dose over 24 h) or 500 mg/kg NaF was similar to that in the animals dosed distilled water (vehicle control)." | 1.27 | Sodium fluoride and chromosome damage (in vitro human lymphocyte and in vivo micronucleus assays). ( Albanese, R, 1987) |
| "Chromosomal aberrations were analysed in metaphase cells of the first mitosis." | 1.27 | [Effect of cell respiration inhibitors on the formation of structural mutations in human lymphocytes irradiated at different stages of the mitotic cycle]. ( Izmaĭlova, NN; Luchnik, NV; Poriadkova, NA, 1985) |
| "Analysis of the effect of NaF on chromosome aberrations induced by Trenimon revealed that pre-, simultaneous and post-treatments significantly enhanced the frequency of undamaged mitoses." | 1.26 | The effect of sodium fluoride on DNA synthesis, mitotic indices and chromosomal aberrations in human leukocytes treated with trenimon in vitro. ( Obe, G; Slacik-Erbn, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (44.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tiwari, H | 1 |
| Rao, MV | 1 |
| Podder, S | 2 |
| Chattopadhyay, A | 2 |
| Bhattacharya, S | 2 |
| Ray, MR | 1 |
| Chakraborty, A | 1 |
| J, M | 1 |
| Sinha, S | 1 |
| Ghosh, M | 1 |
| Mukherjee, A | 1 |
| Luchnik, NV | 2 |
| Tsutsui, T | 7 |
| Suzuki, N | 3 |
| Ohmori, M | 2 |
| Maizumi, H | 1 |
| Matsuda, A | 1 |
| Tanaka, Y | 1 |
| Matsudo, Y | 1 |
| Uehama, A | 1 |
| Someya, T | 1 |
| Hamaguchi, F | 1 |
| Yamamoto, H | 1 |
| Takahashi, M | 1 |
| Oguro, A | 1 |
| Cervenka, J | 1 |
| Horii, K | 1 |
| Aardema, MJ | 2 |
| Kishi, K | 1 |
| Ishida, T | 1 |
| Hayashi, N | 1 |
| Khalil, AM | 1 |
| Zeiger, E | 1 |
| Gulati, DK | 1 |
| Kaur, P | 1 |
| Mohamed, AH | 1 |
| Revazova, J | 1 |
| Deaton, TG | 1 |
| Mihashi, M | 1 |
| Martin, GR | 1 |
| Brown, KS | 1 |
| Matheson, DW | 1 |
| Lebowitz, H | 1 |
| Singer, L | 1 |
| Ophaug, R | 1 |
| Slacik-Erbn, R | 1 |
| Obe, G | 1 |
| Srb, V | 1 |
| Mracková, G | 1 |
| Kubzová, E | 1 |
| Vanícková, H | 1 |
| Michalcová, I | 1 |
| Gibson, DP | 1 |
| LeBoeuf, RA | 1 |
| Scott, D | 1 |
| Roberts, SA | 1 |
| Albanese, R | 1 |
| Thomson, EJ | 1 |
| Kilanowski, FM | 1 |
| Perry, PE | 1 |
| Poriadkova, NA | 1 |
| Izmaĭlova, NN | 1 |
25 other studies available for sodium fluoride and Abnormalities, Autosome
| Article | Year |
|---|---|
Curcumin supplementation protects from genotoxic effects of arsenic and fluoride.
Topics: Adult; Aneuploidy; Antimutagenic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Cells, Cultured | 2010 |
Fluoride-induced genotoxicity in mouse bone marrow cells: effect of buthionine sulfoximine and N-acetyl-L-cysteine.
Topics: Acetylcysteine; Animals; Annexin A5; Apoptosis; Bone Marrow Cells; Buthionine Sulfoximine; Cell Cycl | 2011 |
Reduction in fluoride-induced genotoxicity in mouse bone marrow cells after substituting high fluoride-containing water with safe drinking water.
Topics: Animals; Bone Marrow Cells; Chromosome Aberrations; DNA Damage; Drinking Water; Male; Mice; Sodium F | 2011 |
Evaluation of multi-endpoint assay to detect genotoxicity and oxidative stress in mice exposed to sodium fluoride.
Topics: Animals; Chromosome Aberrations; Comet Assay; DNA Breaks; DNA Damage; Endpoint Determination; Liver; | 2013 |
[Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes].
Topics: 2,4-Dinitrophenol; Adenosine Diphosphate; Chromosome Aberrations; DNA Repair; Floxuridine; Genetic V | 2002 |
Sodium fluoride-induced morphological and neoplastic transformation, chromosome aberrations, sister chromatid exchanges, and unscheduled DNA synthesis in cultured syrian hamster embryo cells.
Topics: Animals; Carcinogens; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; C | 1984 |
Cytotoxicity, chromosome aberrations and unscheduled DNA synthesis in cultured human diploid fibroblasts induced by sodium fluoride.
Topics: Cell Survival; Cells, Cultured; Chromosome Aberrations; DNA; DNA Repair; Humans; Hydroxyurea; Mutati | 1984 |
[Cytogenetic effects of fluoride on human lymphocytes in vitro].
Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Fluorides; Humans; Lymphocytes; | 1980 |
No increases in chromosome aberrations in human diploid fibroblasts following exposure to low concentrations of sodium fluoride for long times.
Topics: Cells, Cultured; Chromosome Aberrations; Diploidy; Fibroblasts; Humans; Sodium Fluoride; Time Factor | 1995 |
Effect of sodium fluoride on chromosomal ploidy and breakage in cultured human diploid cells (IMR-90): an evaluation of continuous and short-time treatment.
Topics: Cell Cycle; Cell Division; Cell Line; Chromosome Aberrations; Chromosome Disorders; Diploidy; Fibrob | 1995 |
Sodium fluoride-induced chromosome aberrations in different cell cycle stages.
Topics: Chromosome Aberrations; G2 Phase; Humans; S Phase; Sodium Fluoride | 1995 |
Clastogenic activity of sodium fluoride in great ape cells.
Topics: Animals; Cell Line; Chi-Square Distribution; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetul | 1993 |
Cell cycle dependence of cytotoxicity and clastogenicity induced by treatment of synchronized human diploid fibroblasts with sodium fluoride.
Topics: Cell Cycle; Chi-Square Distribution; Chromosome Aberrations; Cytological Techniques; Fibroblasts; Hu | 1993 |
Chromosome aberrations in cultured rat bone marrow cells treated with inorganic fluorides.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Female; Fluorides; Male; Methyl | 1995 |
Cytogenetic studies of sodium fluoride in mice.
Topics: Anaphase; Animals; Bone Marrow; Chromosome Aberrations; Cyclophosphamide; Erythrocytes; Male; Metaph | 1994 |
Clastogenic activity of sodium fluoride to rat vertebral body-derived cells in culture.
Topics: Animals; Carcinogens; Cell Survival; Cells, Cultured; Chromosome Aberrations; Male; Mutagens; Osteos | 1996 |
Lack of cytogenetic effects in mice or mutations in Salmonella receiving sodium fluoride.
Topics: Animals; Bone Marrow; Chromosome Aberrations; Chromosomes; Diet; Drug Evaluation, Preclinical; Fluor | 1979 |
The effect of sodium fluoride on DNA synthesis, mitotic indices and chromosomal aberrations in human leukocytes treated with trenimon in vitro.
Topics: Chromosome Aberrations; DNA Replication; Fluorides; Humans; Leukocytes; Mitosis; Mitotic Index; Sodi | 1976 |
[Genotoxic activity test of sodium fluoride in vitro].
Topics: Chromosome Aberrations; Humans; Lymphocytes; Mutagenicity Tests; Sodium Fluoride | 1992 |
[Dependence of lethality and incidence of chromosome aberrations induced by treatment of synchronized human diploid fibroblasts with sodium fluoride on different periods of the cell cycle].
Topics: Cell Cycle; Cells, Cultured; Chromosome Aberrations; Fibroblasts; Humans; Sodium Fluoride | 1989 |
Sodium fluoride-induced chromosome aberrations in different stages of the cell cycle: a proposed mechanism.
Topics: Animals; Aphidicolin; Autoradiography; Biotransformation; Cell Cycle; Cell Line; Chromosome Aberrati | 1989 |
Extrapolation from in vitro tests to human risk: experience with sodium fluoride clastogenicity.
Topics: Cell Line; Cell Survival; Chromosome Aberrations; Dose-Response Relationship, Drug; Humans; Mitomyci | 1987 |
Sodium fluoride and chromosome damage (in vitro human lymphocyte and in vivo micronucleus assays).
Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cyclophosphamide; Humans; Lymphocytes; | 1987 |
The effect of fluoride on chromosome aberration and sister-chromatid exchange frequencies in cultured human lymphocytes.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes; Fluorides; Humans; Lymphocytes; Mitomycin; Mit | 1985 |
[Effect of cell respiration inhibitors on the formation of structural mutations in human lymphocytes irradiated at different stages of the mitotic cycle].
Topics: Chromosome Aberrations; Gamma Rays; Humans; Iodoacetates; Iodoacetic Acid; Lymphocytes; Mitosis; Mut | 1985 |