sodium-ethylxanthate and Stomach-Neoplasms

Topics: Age Factors; Animals; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Precancerous Conditions; Sex; Stomach Neoplasms

Correlation coefficients for age-standardized incidence rates between cancers of the stomach, colon, rectum and lung over place (worldwide) and time (in Connecticut) vary from positive to negative values, indicating that these cancers are not caused by common environmental agents. Correlation coefficients for age-incidence patterns (the variation in age-specific rates with age) between these cancers, on the other hand, are all highly positive for both sexes. We conclude that the carcinogenic determinants that vary with age are common to the cancers studied and to both sexes, and distinct from the carcinogenic determinants that vary with place and time. For the cancers studied, incidence rates are negligible until age 30, at which time they increase dramatically and continue to increase at least until age 75. The rate of increase, however, diminishes continuously with advancing age after 30. We suggest that the role of aging in cancer incidence is determined by two components, one responsible for the dramatic rate increase beginning near age 30 and one responsible for the gradual diminution in that rate increase. The former may correspond to the activation of quiescent cells with damaged DNA or to the deactivation of DNA surveillance or repair or to impaired apoptosis, while the latter may correspond to the loss of cell division potential.

Topics: Adult; Aged; Aging; Colonic Neoplasms; Environment; Female; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Rectal Neoplasms; Registries; Sex; Sex Factors; Stomach Neoplasms; Time Factors

Topics: Adolescent; Adult; Aged; Aging; Female; Humans; Israel; Jews; Male; Middle Aged; Sex; Stomach Neoplasms

Topics: Adult; Aged; Colonic Neoplasms; Esophageal Neoplasms; Ethnology; Female; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Rectal Neoplasms; Sex; Stomach Neoplasms

Topics: Adolescent; Adult; Aged; Amebiasis; Diet; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; Ghana; Humans; Intestinal Neoplasms; Lymphatic Diseases; Male; Middle Aged; Nigeria; Religion; Schistosomiasis; Sex; Stomach Neoplasms

Topics: Adult; Aged; Blood Group Antigens; Colonic Neoplasms; Denmark; Esophageal Neoplasms; Female; Finland; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Norway; Rectal Neoplasms; Sex; Smoking; Stomach Neoplasms; Sweden

Topics: Adult; Aged; Colonic Neoplasms; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Iceland; Male; Middle Aged; Rectal Neoplasms; Sex; Stomach Neoplasms

Topics: Adolescent; Adult; Aged; Child; Colonic Neoplasms; Egypt; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Intestine, Small; Male; Middle Aged; Mouth Neoplasms; Rectal Neoplasms; Sex; Stomach Neoplasms

Topics: Adolescent; Adult; Aged; Bolivia; Brazil; California; Chile; Colombia; Colonic Neoplasms; England; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Male; Middle Aged; Rectal Neoplasms; Sampling Studies; Sex; Stomach Neoplasms; Venezuela

Topics: Adolescent; Adult; Aged; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Male; Middle Aged; Rwanda; Schistosomiasis; Sex; Stomach Neoplasms; Uganda

Topics: Adolescent; Adult; Aged; Black or African American; Black People; Child; Child, Preschool; Esophageal Neoplasms; Ethnology; Female; Gastrointestinal Neoplasms; Humans; Infant; Intestinal Neoplasms; Male; Middle Aged; Sex; Social Conditions; Stomach Neoplasms; Zimbabwe

Topics: Adenocarcinoma, Mucinous; Adult; Aged; Black or African American; Black People; Colonic Neoplasms; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Nitrosamines; Rectal Neoplasms; Sex; South Africa; Stomach Neoplasms

Topics: Adenocarcinoma; Adult; Aged; Aging; Alcoholic Beverages; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Radiography; Retrospective Studies; Sex; Smoking; Social Conditions; Stomach Neoplasms

Topics: Biliary Tract; Bronchial Neoplasms; Esophageal Neoplasms; Ethnology; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Rectal Neoplasms; Sex; Stomach Neoplasms

Topics: Adult; Aged; Aging; Ethnology; Female; Humans; Male; Middle Aged; Sex; Stomach Neoplasms; Stomach Ulcer; United States; White People

Topics: ABO Blood-Group System; Adenocarcinoma; Adenocarcinoma, Scirrhous; Blood Group Antigens; Carcinoma; Genetics, Medical; Geriatrics; Neoplasms; Sex; Stomach Neoplasms

Topics: Aging; Arteriosclerosis; Asthma; Blindness; Dementia; Emphysema; Geriatrics; Hexosamines; Humans; Hypertension; Leukemia; Lung Neoplasms; Lymphogranuloma Venereum; Male; Neoplasms; Prostatic Hyperplasia; Psychotic Disorders; Scoliosis; Sex; Stomach Neoplasms; Stomach Ulcer; Urine

Topics: Adolescent; Altitude; Female; Geriatrics; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Peru; Sex; Stomach Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms

Topics: Adolescent; Chronic Disease; Gastric Acidity Determination; Gastritis; Gastroscopy; Geriatrics; Humans; Occult Blood; Pathology; Polyps; Radiography; Sex; Stomach Neoplasms; Stomach Ulcer

Topics: Aging; Gastrectomy; Gastroscopy; Japan; Neoplasms; Pathology; Photography; Polyps; Prognosis; Sex; Stomach Neoplasms

Topics: Aging; Gastrectomy; Gastroscopy; Japan; Neoplasms; Pathology; Photography; Polyps; Prognosis; Sex; Stomach Neoplasms

Topics: Connecticut; Denmark; England; Finland; France; Geriatrics; Neoplasms; Norway; Sex; Stomach Neoplasms; Surgical Procedures, Operative; United States; Wales

Topics: Aging; Betazole; Digestion; Gastric Juice; Humans; Peptic Ulcer; Sex; Stomach Neoplasms

Topics: Aging; Neoplasms; Pathology; Peptic Ulcer; Sex; Statistics as Topic; Stomach Neoplasms; Stomach Ulcer

Topics: Adenocarcinoma; Aging; Carcinoma; Carcinoma, Squamous Cell; Classification; Gastrectomy; Geriatrics; Humans; Japan; Neoplasm Metastasis; Neoplasms, Second Primary; Pathology; Sex; Stomach Neoplasms