sodium-ethylxanthate and Peptic-Ulcer-Perforation

Because no large series of perforated peptic ulcers has been reported from Canada, 402 cases from the Ottawa Civic Hospital were reviewed to study this dramatic disorder.The incidence was 15 per 100,000 population annually, or one in every 1000 hospital admissions.The incidence in females and the elderly in this series was higher than reported elsewhere. The risk of perforation increased with age, being greatest after 55; this was not due to an excess of chronic ulcers in older patients, indicating that ageing is an etiological factor.As the mortality of perforated peptic ulcer-20%-had remained unchanged over the years, fatal cases were studied to see if changes should be made in the management of this condition. The mortality for patients undergoing operation was 7.5%. Patients treated conservatively because their general condition was poor, died. Fifteen patients, in whom an incorrect diagnosis was made, died. More aggressive therapy and greater efforts at diagnosis might have saved some of these patients.

Topics: Adult; Aged; Aging; Female; Humans; Male; Middle Aged; Ontario; Peptic Ulcer Perforation; Seasons; Sex

Topics: ABO Blood-Group System; Adult; Aging; Duodenal Ulcer; England; Female; Humans; Male; Middle Aged; Peptic Ulcer Perforation; Sex; Stomach Ulcer

Topics: Adolescent; Adult; Aged; Aging; Child; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Peptic Ulcer Perforation; Pylorus; Scotland; Seasons; Sex; Stomach Ulcer

Topics: Adolescent; Aging; Alcoholism; Black People; Child; Cortisone; Duodenal Ulcer; Geriatrics; Humans; Infant; Mortality; Peptic Ulcer Perforation; Peritonitis; Seasons; Sex; Smoking; Surgical Procedures, Operative; Toxicology; White People

Topics: Black People; Drug Therapy; Duodenal Ulcer; Gastrectomy; Humans; Peptic Ulcer Perforation; Prognosis; Sex; Statistics as Topic; Stomach Ulcer; Vagotomy

Topics: Aged; Aspirin; Duodenal Ulcer; Dyspepsia; Female; Humans; Male; Middle Aged; Peptic Ulcer Perforation; Pylorus; Sex; Stomach Ulcer

Topics: Aging; Humans; Incidence; Peptic Ulcer Perforation; Scotland; Seasons; Sex; Statistics as Topic

Big differences in the prevalence of peptic ulcer are known to exist in different parts of India. This paper reports a high incidence in Assam and records certain differences with peptic ulcers found in south India.

Topics: Aging; Epidemiology; Hematemesis; Humans; Humidity; India; Melena; Occupational Medicine; Peptic Ulcer; Peptic Ulcer Hemorrhage; Peptic Ulcer Perforation; Prevalence; Railroads; Sex; Statistics as Topic

Topics: Abdominal Injuries; Duodenal Ulcer; Humans; Peptic Ulcer Perforation; Sex; Sex Characteristics; Stomach Diseases; Thoracic Injuries