sodium-ethylxanthate and Papilloma

We assessed the prevalence of human papillomavirus (HPV) by cervicovaginal lavage and Southern blot and inquired about behavioral risk factors for cervical disease and sexually transmitted diseases by interview in 114 female detainees at a large New York City jail. Of the women screened, 8% had abnormal Pap smears, 35% had HPV, 7% had gonorrhea, and 22% had serologic syphilis. Given the high rates of HPV infection and cervical cytology, Pap smears should be a routine intake procedure for incarcerated women.

Topics: Adult; Contraceptive Devices, Male; Cross-Sectional Studies; Female; Humans; New York City; Papanicolaou Test; Papilloma; Prisoners; Sex; Sexually Transmitted Diseases, Bacterial; Tumor Virus Infections; Uterine Cervical Dysplasia; Vaginal Smears

Topics: Adolescent; Adult; Child; Humans; Male; Papilloma; Penile Diseases; Penile Neoplasms; Sex

Hibernating European hamsters reacted differently to sc injections of N-nitrosodiethylamine (DEN) than did European hamsters that were not hibernating. Hibernating animals tolerated higher dose levels but developed fewer neoplasms. In contrast, hibernating males had more pulmonary tumors than did the respective nonhibernators. However, the hibernating females of the low dosage group developed fewer lung tumors. The survival times were longer for the male hibernators than for the male nonhibernators. The organ specificity of DEN, as well as the morphology and histogenesis of the neoplasms, showed no differences between the hibernating and nonhibernating groups.

Topics: Adenocarcinoma; Animals; Basement Membrane; Carcinoma, Squamous Cell; Cricetinae; Diethylnitrosamine; Female; Hibernation; Lethal Dose 50; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Papilloma; Sex; Species Specificity