sodium-ethylxanthate and Hodgkin-Disease

Topics: Hodgkin Disease; Humans; Neoplasms; Pathology; Prognosis; Radiotherapy, High-Energy; Sex

Although the sex of an individual confers one of the greatest of the known risks for contracting leukaemia and lymphomas, very little attention is paid to these risks. It is the purpose of this paper to stimulate further research in this area. The sex rate ratios are presented for the commoner haematological malignancies. The male excess in the lymphoid cancers is most marked in the youngest age group in non-Hodgkin's lymphoma and Hodgkin's disease, while acute lymphoblastic leukaemia shows equal sex ratios in the childhood peak. Both chronic lymphocytic leukaemia and lymphocytic lymphoma display an unusual pattern, hitherto undescribed, with a large male excess specific to the 40s and 60s age groups. The myeloid sex ratios are all characterized by slight female excess in early adulthood followed by marked male excess. The reasons for these patterns are discussed.

Topics: Acute Disease; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Hematologic Neoplasms; Hodgkin Disease; Humans; Incidence; Infant; Infant, Newborn; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk; Sex; Sex Distribution

Topics: Adult; Body Image; Counseling; Female; Gender Identity; Hodgkin Disease; Humans; Models, Theoretical; Role; Self Concept; Sex

Topics: Female; HLA Antigens; Hodgkin Disease; Humans; Male; Sex

Serum copper determinations were routinely performed in 141 men and 100 women with histologically verified Hodgkin's disease, admitted to the Radium Centre for Jutland over a 10-year-period from January 1, 1963, to January 1, 1973. The previously described variations in serum copper with the activity of the disease, increasing with progression and decreasing with improvement, were amply substantiated. Furthermore, the present study showed that the serum copper value at the first admission, before treatment, is statistically significantly correlated to the stage of the disease and consequently probably to the amount of tumor tissue. In men there was also a statistically significant correlation of se Cu to the histologic grade of the bioptic material (classification according to Lukes 1966). In women the correlation was blurred by the effect on serum copper of estrogen, mainly from contraceptive pills and pregnancy. The serum copper is regularly reduced to within normal limits at complete remission; thus, it is proposed that this parameter be included in the criteria for complete remission.

Topics: Adolescent; Adult; Aged; Ceruloplasmin; Child; Copper; Estrogens; Female; Hodgkin Disease; Humans; Liver; Male; Middle Aged; Pregnancy; Remission, Spontaneous; Retrospective Studies; Sex

Topics: Adult; Aged; Celiac Disease; Female; Hodgkin Disease; Humans; Intestine, Small; Lymphoma; Male; Middle Aged; Prognosis; Sex

Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Czechoslovakia; Female; Hodgkin Disease; Humans; Longevity; Male; Middle Aged; Neoplasm Recurrence, Local; Sex

Topics: Aging; Biometry; Drug Therapy; Geriatrics; Hodgkin Disease; Neoplasms; Pathology; Prognosis; Sex

Topics: Adolescent; Antineoplastic Agents; Child; Hodgkin Disease; Humans; Neoplasms; Palliative Care; Sex