sodium-ethylxanthate and Coronary-Disease

It has been recognized over the past years that women form a distinct subpopulation within patients with coronary heart disease. This phenomenon should be acknowledged in the management and in the assessment of coronary heart disease. Over the past years remarkable progress has been made concerning our knowledge of cardiovascular risk factors related to gender. For instance, diabetes, high density lipoproteins and triglycerides levels have been found to have a greater impact on coronary heart disease risk in women compared to men. On the other hand, evidence showing that lipoprotein (a) is a cardiovascular risk factor seems to be stronger in men than in women. For optimal treatment and prevention of coronary heart disease it is necessary to acknowledge that it is not self-evident that women and men show similar responses to risk factors or to treatment. This review article addresses the role of cardiovascular risk factors focusing on the differential impact they might have on men and women.

Topics: Aged; Bacterial Infections; Biomarkers; C-Reactive Protein; Coronary Disease; Diabetes Complications; Estrogens; Female; Fibrinogen; Homocysteine; Humans; Hypertension; Inflammation; Lipid Metabolism; Male; Middle Aged; Obesity; Psychosocial Deprivation; Risk Factors; Sex; Smoking; Triglycerides

Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Death, Sudden, Cardiac; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Patient Selection; Sex

In the effort to explain gender-related differences of the cardiovascular system, the renin-angiotensin system experienced intensive exploration. Indeed, the development of hypertension as well as the progression of coronary artery disease and heart failure have two factors in common: (1) display distinct gender specific characteristics and (2) are enhanced by the renin-angiotensin system. It is therefore interesting to note that data from experimental animals, epidemiological surveys, and clinical investigations suggest that the components of the circulating as well as tissue-based renin-angiotensin system are markedly affected by gender. However, the issue is complicated by counter-regulatory effects of estrogen on the system with the substrate, on one hand, and the processing enzymes as well as the chief receptor, on the other hand. In fact, angiotensinogen is up-regulated particularly by oral administration of estrogen, whereas renin, angiotensin-converting enzyme (ACE), and AT-1 receptor are down-regulated by the hormone. While under well-defined experimental conditions the net effect of estrogen appears to result in suppression of the renin-angiotensin system, the clinical situation may be more complex. The judgment is further complicated by the difficulty in precisely measuring the activity of the system at the tissue level. Moreover, clinically relevant read-outs for the activity of the renin-angiotensin system may be regulated multifactorially or only indirectly affected by the system. Nevertheless, the undisputable, profound biochemical changes in the renin-angiotensin system related to the estrogen status allow speculation that such interaction explains some of the differences in the cardiovascular system of men and women.

Topics: Angiotensin I; Cardiovascular Physiological Phenomena; Coronary Disease; Estrogens; Female; Genotype; Heart Failure; Humans; Hypertension; Male; Renin; Renin-Angiotensin System; Sex

Topics: Adult; Aged; Coronary Disease; Decision Making; Female; Humans; Information Systems; Male; Middle Aged; Patient Selection; Prejudice; Sex

Topics: Adrenergic beta-Antagonists; Aging; Anti-Anxiety Agents; Anxiety; Coronary Disease; Heart; Hemodynamics; Humans; Hypertension; Life Change Events; Risk Factors; Sex; Sleep; Social Adjustment; Stress, Physiological

Topics: Body Constitution; Coronary Disease; Diabetes Mellitus; Dietary Fats; Genetics, Medical; Glycerides; Humans; Hypercholesterolemia; Hypertension; Lipids; Lipoproteins; Obesity; Peptic Ulcer; Physical Exertion; Sex; Smoking; Stress, Physiological; Thyroid Diseases

To examine the relation between social behaviour and vagal activity, the communal behaviour of healthy college men (N = 33) and women (N = 33) was manipulated while monitoring heart rate (HR) and respiratory sinus arrhythmia (RSA). The subjects were classified as low or high on communal trait. Communal behaviour was manipulated by having the subjects behave in an agreeable or quarrelsome manner in scripted role-plays. HR, RSA and self-report arousal were obtained during or immediately following baseline, experimental and relaxation periods. 2 (Gender) x 2 (Communal Trait; low/high) x 2 (Condition; agreeable/quarrelsome) ANCOVAs were performed. Men had lower RSA values when behaving in a quarrelsome fashion than agreeable and lower RSA values than women in the quarrelsome condition. In the latter condition, low communal men reported more arousal than other groups. Strong but opposite associations between RSA and affect arousal were observed in low communal men and woman. Men, especially more quarrelsome (less communal) men exhibited weaker vagal control during arousing social situations.

Topics: Adolescent; Adult; Arousal; Arrhythmia, Sinus; Cardiovascular Physiological Phenomena; Coronary Disease; Emotions; Female; Heart Rate; Hostility; Humans; Interpersonal Relations; Male; Multivariate Analysis; Regression Analysis; Respiration; Sex; Social Behavior; Stress, Psychological

The author presents studies suggesting that anticoagulants are not indicated in completed stroke except when it is caused by an embolus from a well-defined cardiac source. Preferred and alternate treatment and therapy for stroke and threatened stroke is discussed.

Topics: Anticoagulants; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Humans; Ischemic Attack, Transient; Platelet Aggregation; Random Allocation; Risk; Sex; Tomography, X-Ray Computed

Osteoprotegerin (OPG), a key factor in bone remodeling and vascular calcification, has been suggested to be associated with cardiovascular events. This study sought to assess the relationship between plasma OPG, anthropometric, metabolic status, severity and extent of coronary artery calcification, and the two-year recurrence risk of coronary event in patients with coronary heart disease (CHD).. A total of 155 consecutive patients with symptoms suggestive of CHD were enrolled in this cross-sectional study. Blood samples were taken for laboratory tests. Coronary angiography and cardiac CT scan were performed to assess the severity and extent of involved vessels. Two-year risk of subsequent CHD was estimated based on the computational Framingham risk prediction model.. OPG level was in direct linear association with age (β = 0.38, p < 0.001), waist to hip ratio (β = 0.17, p < 0.05), hs-CRP (β = 0.17, p < 0.05), systolic and diastolic blood pressure (β = 0.17, p < 0.05; β = 0.23, p < 0.01), and HbA1c (β = 0.17, p < 0.05). After age-sex adjustment, only HbA1c (β = 0.15, p < 0.05) was a significant indicator of serum OPG. OPG showed significant linear association with the coronary calcium score (CCS), and the number of involved vessels even after adjustment for age, sex, diabetes, blood pressure, and markers of bone-calcium metabolism (β = 0.27, P < 0.05; β = 29, P < 0.01). There is a significant positive association between two-year risk of subsequent CHD and serum OPG in females (β = 0.45, P < 0.01) but not in males.. Increased OPG is independently associated with the severity and extent of CHD. This study also proposes OPG as a potential marker in predicting the risk of subsequent CHD, in females.

Topics: Coronary Angiography; Coronary Disease; Cross-Sectional Studies; Female; Heart; Humans; Male; Middle Aged; Osteoprotegerin; Risk Factors; Severity of Illness Index; Sex; Tomography, X-Ray Computed; Waist-Hip Ratio

Topics: Coronary Disease; Feeding Behavior; Female; Humans; Male; Risk Factors; Sex; Sex Factors; Terminology as Topic

Topics: Aged; Angina Pectoris; Attitude of Health Personnel; Cardiac Catheterization; Chest Pain; Coronary Disease; Female; Humans; Male; Middle Aged; Patient Simulation; Physicians; Racial Groups; Sex

We analyzed potential gender differences in the use and prognostic value of stress technetium 99m sestamibi tomography, image results, and cardiac event rates over a period of 15 +/- 8 months in 1226 men and 1151 women. Men had more abnormal tomographic images, but referral for catheterization and revascularization similarly increased in relation to the number of defects. Men and women with abnormal images had similar event rates, 19.6% and 18.2%, respectively, although men more often had myocardial infarction or cardiac death (7.6% vs 4.1 %, p < 0.05), whereas women had an increased likelihood of unstable angina or congestive heart failure (11.5% vs 7.6%, p < 0.05). Normal images predicted a low yearly rate of myocardial infarction or death: 1.7% for men and 0.8% for women. Image findings, particularly defect extent, were independent predictors of events in both groups. Thus, after stress Tc-99m sestamibi single-photon emission computed tomography perfusion imaging, there was no gender bias in referral for invasive procedures, and for both men and women image findings were strongly associated with prognostic outcome.

Topics: Angina Pectoris; Angina, Unstable; Cardiac Catheterization; Coronary Disease; Death, Sudden, Cardiac; Dipyridamole; Exercise Test; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Physician-Patient Relations; Predictive Value of Tests; Prognosis; Radiopharmaceuticals; Referral and Consultation; Regression Analysis; Selection Bias; Sex; Sex Factors; Stress, Physiological; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

To determine the relative risks of nonfatal myocardial infarction (MI) triggered by sexual activity among the general population and in patients with prior coronary heart disease.. Relative risks and effect modification were calculated by the case-crossover method, a new epidemiologic technique designed to quantify the transient change in risk following exposure to a potential disease trigger.. A total of 1774 patients with MI were interviewed in 45 hospitals throughout the United States. Data were gathered on potential triggers of MI occurring immediately prior to the event and during the previous year. Results are presented for the 858 patients who were sexually active in the year prior to the MI, with attention to the 273 patients who had coronary artery disease prior to their index MI, and the effect of regular exertion on risk.. The relative risk of nonfatal MI following sexual activity.. Of the 858 patients, 79(9%) reported sexual activity in the 24 hours preceding MI, and 27(3%) reported sexual activity in the 2 hours preceding onset of symptoms of MI. The relative risk of MI occurring in the 2 hours after sexual activity was 2.5(95% confidence interval [CI], 1.7-3.7). The relative risk of triggering onset of MI among patients with a history of prior angina (2.1 [95% CI, 0.8-5.8]) or prior MI (2.9 [95% CI, 1.3-6.5]) was not greater than that observed in those without prior cardiac disease. Sexual activity was a likely contributor to the onset of MI in only 0.9% of cases and regular exertion was associated with decreasing risk.. Sexual activity can trigger the onset of MI. However, the relative risk is low, and since the absolute hourly risk of MI is extremely low, the absolute risk increase caused by sexual activity also is extremely low (1 chance in a million for a healthy individual). Moreover, the relative risk is not increased in patients with a prior history of cardiac disease and regular exercise appears to prevent triggering. These findings should be useful for counseling patients and decreasing the fear of sexual activity that often prevents complete rehabilitation from cardiovascular disease.

Topics: Adult; Aged; Confidence Intervals; Coronary Disease; Epidemiologic Methods; Exercise; Female; Humans; Male; Middle Aged; Myocardial Infarction; Physical Exertion; Risk; Sex

A descriptive, correlational approach was used to examine the relationship between success with a recommended cardiac lifestyle and satisfaction with a cardiac rehabilitation programme 1 year following completion. The Cardiac Lifestyle Questionnaire (CLQ) and the Programme Satisfaction Questionnaire (PSQ) evaluated success in eight lifestyle dimensions and four satisfaction areas. Seventy-two participants (85.7%) returned questionnaires. Successful lifestyle dimensions included exercise, tobacco, alcohol and weight; diet, stress and hypertension were unsuccessful. Two open-ended programme satisfaction questions revealed that 'caring' and 'individualized' approaches were most favoured by participants. These provide direction for high-quality care in cardiac rehabilitation programmes. Discriminant analysis did not yield a statistically significant separation of groups relative to cardiac lifestyle on the basis of programme satisfaction areas.

Topics: Adult; Aged; Angina Pectoris; Coronary Artery Bypass; Coronary Disease; Discriminant Analysis; Education; Female; Follow-Up Studies; Humans; Life Style; Male; Marital Status; Middle Aged; Myocardial Infarction; Patient Satisfaction; Sex; Surveys and Questionnaires; Time Factors

Topics: Aging; Angina Pectoris; Coronary Disease; Energy Metabolism; Humans; Sex

Topics: Coronary Disease; Coronary Thrombosis; Female; Humans; Male; Sex

Topics: Coronary Disease; Diseases in Twins; Down Syndrome; Environment; Female; Genetic Diseases, Inborn; Humans; Hypertrophy; Male; Models, Genetic; Neural Tube Defects; Pregnancy; Pyloric Stenosis; Random Allocation; Schizophrenia; Sex; Twins, Dizygotic; Twins, Monozygotic

Topics: Coronary Disease; Family Characteristics; Female; Heart Diseases; Humans; Male; Menstruation; Pregnancy; Sex

Topics: Coronary Disease; Humans; Myocardial Infarction; Sex; Uric Acid

Topics: Aged; Cholesterol; Coronary Disease; Diet; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Sex; Smoking

The object of this study was to investigate the relationship between residence, occupation and smoking habits, and mortality from chronic diseases, particularly lung cancer. It was a prospective study, initiated by a questionnaire sent to Canadian veteran pension recipients. The study was based on the replies of 78,000 males and 14,000 females, together with data on the deaths occurring among these respondents over a six-year follow-up period-July 1, 1956 to January 30, 1962.The outstanding finding of this study was that cigarette smokers compared to non-smokers had excessive mortality, particularly from heart and circulatory diseases, lung cancer, and bronchitis and emphysema. The mortality ratios for heart and circulatory diseases were elevated even for those who smoked cigarettes less than five years, and remained relatively constant as the duration of smoking increased. The mortality ratios for lung cancer increased markedly as the duration of smoking increased. A small excess in mortality was noted among urban residents. An association between cause of death and occupation was not evident in this study.Findings based on the data on smoking collected in this study were incorporated into the Report of the U.S. Surgeon-General's Advisory Committee on Smoking and Health.

Topics: Adult; Bronchitis; Canada; Cardiovascular Diseases; Coronary Disease; Female; Humans; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Pulmonary Emphysema; Sex; Smoking

Topics: Adult; Angina Pectoris; Blood Pressure; Body Weight; Cholesterol; Coronary Disease; Death, Sudden; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Obesity; Sex

Topics: Adolescent; Adult; Black or African American; Black People; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Electrocardiography; Ethnology; Female; Glucose Tolerance Test; Glycosuria; Humans; Hypertension; Male; Middle Aged; Potassium; Religion; Sex; South Africa; Urea

Topics: Animals; Arteriosclerosis; Behavior, Animal; Coronary Disease; Diazepam; Female; Male; Myocardium; Necrosis; Poultry; Sex

Topics: Adult; Aged; Aging; Biometry; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Humans; Male; Middle Aged; Myocardial Infarction; Occupations; Sex

Topics: Aging; Coronary Disease; Education; Ethnology; Humans; Models, Theoretical; Occupations; Population; Religion; Sex; Social Conditions; Statistics as Topic; Stress, Physiological

Topics: Coronary Disease; Female; Humans; Male; Poland; Sex

Topics: Adult; Aged; Aging; Cardiomyopathies; Coronary Disease; Electrocardiography; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Myocardium; Myxedema; Organ Size; Pericardial Effusion; Sex

Topics: Adolescent; Adult; Aged; Aging; Aorta; Aortic Diseases; Arteriosclerosis; Brachiocephalic Trunk; Carotid Arteries; Child; Child, Preschool; Coronary Disease; Coronary Vessels; Female; Humans; Iliac Artery; India; Male; Middle Aged; Sex

Topics: Cerebrovascular Disorders; Coronary Disease; Female; Humans; Italy; Male; Sex; Social Conditions

Topics: Coronary Disease; Ethnology; Female; Humans; Hypertension; Male; Mortality; Sex; United States

Topics: Adolescent; Adult; Aged; Aging; Angina Pectoris; Aortic Diseases; Arteries; Arteriosclerosis; Cholesterol; Coronary Disease; Female; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Myocardial Infarction; Phospholipids; Sex; Thrombosis

Topics: Adult; Aging; Coronary Disease; Female; Humans; In Vitro Techniques; Lipids; Male; Middle Aged; Poland; Sampling Studies; Sex

Topics: Adult; Aging; Calcinosis; Cineangiography; Coronary Disease; Female; Humans; Male; Middle Aged; Radiography, Thoracic; Sex

Topics: Animals; Blood Pressure; Cholesterol; Coronary Disease; Diet, Atherogenic; Female; Hypercholesterolemia; Hypertension, Renal; Lipid Metabolism; Male; Nephrectomy; Rats; Sex

A retrospective study was designed to determine the background characteristics of 9562 patients hospitalized in Saskatchewan during the calendar years 1958-1959-1960 with a discharge diagnosis of heart disease specified as involving the coronary arteries. The study illustrates the limitations of retrospective analyses, but points out that such analyses may highlight presumptive relevant variables in the search for causes of diseases with multiple possible interacting origins. Single persons, and in particular single females, were significantly much less susceptible than were persons who were married or who had been married. This is a previously unreported finding, to the authors' knowledge. Residents of farms and hamlets were hospitalized significantly less often than were village, town or city residents; it is suggested that this may corroborate the findings of Morris and others who feel that the physical activity of work may be a relevant variable in the etiology of coronary heart disease.

Topics: Adolescent; Aging; Canada; Child; Coronary Artery Disease; Coronary Disease; Diet; Environment; Geriatrics; Hospitalization; Humans; Infant; Infant, Newborn; Marriage; Mortality; Occupations; Retrospective Studies; Saskatchewan; Sex; Statistics as Topic

Topics: Aging; Cholesterol; Coronary Disease; Geriatrics; Lipid Metabolism; Lipids; Sex; Statistics as Topic

Topics: Aging; Blood Pressure; Blood Pressure Determination; Cholesterol; Coronary Artery Disease; Coronary Disease; Dietary Fats; Humans; Lipids; Sex; Sri Lanka; Statistics as Topic

Topics: Aging; Body Weight; Cardiomegaly; Coronary Disease; Electrocardiography; Humans; Hypertrophy, Left Ventricular; Sensitivity and Specificity; Sex

Topics: Chemistry Techniques, Analytical; Cholesterol; Coronary Disease; Dietary Fats; Fats, Unsaturated; Fatty Acids; Feeding Behavior; Humans; Mortality; Sex

Topics: Aortic Diseases; Arteriosclerosis; Atherosclerosis; Coronary Disease; Geriatrics; Neoplasms; Sex; Statistics as Topic; Syndrome

Topics: Black People; Cholesterol; Coronary Artery Disease; Coronary Disease; Diet; Epidemiology; Georgia; Geriatrics; Humans; Occupations; Physical Exertion; Sex; Sociology; White People

Topics: Adolescent; Aging; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cholesterol; Coronary Disease; Epidemiologic Studies; Epidemiology; Geriatrics; Heart Defects, Congenital; Heart Failure; Humans; Hypertension; Michigan; Obesity; Rheumatic Heart Disease; Sex; Smoking

Topics: Adolescent; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Epidemiology; Geriatrics; Humans; Hyperglycemia; Hypertension; Michigan; Sex; Vascular Diseases

Topics: Coronary Disease; Diagnosis; Electrocardiography; Epidemiologic Studies; Epidemiology; Humans; Morbidity; Mortality; Reproducibility of Results; Sex

Topics: Aging; Aortic Diseases; Arteriosclerosis; Atherosclerosis; Coronary Disease; Geriatrics; Lipid Metabolism; Nutrition Disorders; Sex; Statistics as Topic

Topics: Adult; Coronary Disease; Female; Humans; Male; Middle Aged; Pelvimetry; Sex; Somatotypes; United States; White People

Topics: Adult; Aged; Arteriosclerosis; Coronary Disease; Epidemiologic Methods; Epidemiology; Female; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Mortality; Sex

Topics: Aging; Animals; Behavior, Animal; Coronary Disease; Poultry; Sex; Social Conditions; Stress, Physiological

Topics: Adult; Aged; Aging; Arteriosclerosis; Black or African American; Calcinosis; Coronary Disease; Female; Geography; Humans; Louisiana; Male; Middle Aged; Sex

Topics: Adolescent; Adult; Aged; Aging; Arteriosclerosis; Cholesterol; Coronary Disease; Female; Histocytochemistry; Humans; Male; Middle Aged; Phospholipids; Sex; Statistics as Topic

Topics: Adolescent; Adult; Aged; Aging; Aortic Diseases; Child; Coronary Disease; Female; Humans; In Vitro Techniques; Intracranial Arteriosclerosis; Male; Middle Aged; Sex

Topics: Aging; Arteriosclerosis; Brazil; Centrifugation; Chemistry Techniques, Analytical; Cholesterol; Coronary Disease; Epidemiology; Geriatrics; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lipoproteins, LDL; Sex; Spectrophotometry

Topics: Adolescent; Arteriosclerosis; Body Weight; Cholesterol; Coronary Disease; Epidemiology; Ethnology; Geriatrics; New York; Sex

Topics: Arteriosclerosis; Atherosclerosis; Autopsy; Coronary Artery Disease; Coronary Disease; Death, Sudden; Death, Sudden, Cardiac; Humans; Poland; Sclerosis; Sex; Statistics as Topic

Topics: Arrhythmias, Cardiac; Arteriosclerosis; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Cardiomegaly; Coronary Disease; Geriatrics; Heart Block; Heart Diseases; Heart Failure; Hypertension; Myocardial Infarction; Obesity; Sex; Statistics as Topic

Topics: Absorption; Achlorhydria; Aging; Arteriosclerosis; Blood Chemical Analysis; Cholesterol; Coronary Disease; Dietary Fats; Fats, Unsaturated; Geriatrics; Humans; Lipids; Obesity; Physical Exertion; Sex; Stress, Physiological

Topics: Aged; Arteriosclerosis; Bundle-Branch Block; Calcinosis; Cardiac Conduction System Disease; Coronary Disease; Electrocardiography; Geriatrics; Heart; Heart Block; Humans; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Stenosis; Pathology; Radiography, Thoracic; Rheumatic Heart Disease; Sex

Topics: Aorta, Abdominal; Aortic Diseases; Black People; Calcinosis; Coronary Artery Disease; Coronary Disease; Geriatrics; Humans; Pathology; Sex; White People

Topics: Angina Pectoris; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus; Digitalis Glycosides; Drug Therapy; Electrocardiography; Epidemiology; Female; Geriatrics; Heart Block; Humans; Incidence; Myocardial Infarction; Sex

Topics: Aging; Angina Pectoris; Body Weight; California; Cholesterol; Coronary Disease; Ethnology; Follow-Up Studies; Geriatrics; Humans; Hypertension; Los Angeles; Myocardial Infarction; Sex; Statistics as Topic

Topics: Aging; Cardiovascular Diseases; Coronary Disease; Humans; Kidney Diseases; Life Expectancy; Mortality; Public Health; Sex; Statistics as Topic; United States

Topics: Coronary Artery Disease; Coronary Disease; England; Epidemiology; Geriatrics; Humans; Male; Mortality; Prevalence; Sex; Wales

Topics: Adolescent; Aging; Cholesterol; Coronary Disease; Geriatrics; Hypercholesterolemia; Hyperlipidemias; Lipid Metabolism; Myocardial Infarction; Sex; Statistics as Topic; Triglycerides

Viscosity of whole blood and plasma was measured in 258 apparently healthy subjects of both sexes from 5 to 60 years of age, and in 86 patients with unequivocal evidence of chronic coronary heart disease. Children and young healthy females had the lowest viscosity readings. Healthy young and middle-aged males had significantly higher blood viscosity than females. Patients with coronary heart disease had significantly higher blood viscosity values than healthy groups of the same sex. It is suggested that the higher viscosity of whole blood and of plasma is a contributory factor in development of clinical manifestations of coronary heart disease and possibly of the basic vascular lesion itself.

Topics: Adolescent; Aging; Arteriosclerosis; Blood Viscosity; Child; Coitus; Coronary Artery Disease; Coronary Disease; Female; Geriatrics; Healthy Volunteers; Humans; Infant; Male; Middle Aged; Plasma; Sex; Statistics as Topic

Topics: Adolescent; Aging; Arteriosclerosis; Biomedical Research; Cholesterol; Coronary Disease; Geriatrics; Hungary; Hypercholesterolemia; Hyperlipidemias; Lipid Metabolism; Lipids; Serum; Sex; Statistics as Topic

Topics: Adipose Tissue; Alopecia; Aortic Diseases; Atrophy; Calcinosis; Cockayne Syndrome; Coronary Disease; Dihydrotachysterol; Emaciation; Kidney Diseases; Kyphosis; Muscular Atrophy; Osteosclerosis; Pathology; Pharmacology; Progeria; Rats; Research; Sex; Sex Characteristics; Skin Diseases; Tooth Abnormalities; Toxicology

Topics: Aging; Autopsy; Coronary Artery Disease; Coronary Disease; Geriatrics; Humans; Mast Cells; Myocardial Infarction; Myocardium; Pathology; Sex; Statistics as Topic

Topics: Adolescent; Black People; Cholesterol; Coronary Disease; Ethnology; Geriatrics; Humans; Myocardial Infarction; New York; Sex; Statistics as Topic; White People

Topics: Adolescent; Aging; Angiography; Arm; Arteries; Arteriosclerosis Obliterans; Coronary Disease; Electronic Data Processing; Epidemiology; Femoral Artery; Humans; Iliac Artery; Leg; Mass Screening; Palpation; Pulse; Sex; Switzerland; Vascular Diseases

Topics: Aging; Blood Pressure; Body Weight; Cholesterol; Coronary Disease; Dietary Fats; Epidemiologic Studies; Humans; Hypertension; Japan; Rural Population; Sex

Topics: Aortic Diseases; Arteriosclerosis; Atherosclerosis; Black People; Coronary Disease; Humans; Louisiana; New Orleans; Pathology; Sex; White People

Topics: Adolescent; Aging; Angiography; Child; Coronary Disease; Coronary Vessels; Geriatrics; Heart Defects, Congenital; Histology; Humans; Hypertension; Infant; Infant, Newborn; Pulmonary Heart Disease; Sex