sodium-ethylxanthate and Aphasia

Two experiments investigated phonological, derivational-morphological and semantic aspects of grammatical gender assignment in a perception and a production task in German aphasic patients and age-matched controls. The agreement of a gender indicating adjective (feminine, masculine or neuter) and a noun was evaluated during perception in Experiment 1 (grammaticality judgment). In Experiment 2 the same participants had to produce the matching definite article to a noun. In the perception task patients with left frontal lesions (LF) made more errors during phonological gender assignment as compared to derivational-morphological and semantic gender assignment, while patients with lesions of the posterior superior temporal gyrus (pSTG) made more errors in derivational-morphological gender assignment as compared to phonological and semantic gender assignment. In the production task no differences between patient groups were found. These data support previous evidence that left frontal brain areas are critically involved in phonological processing. The pSTG on the other hand may be critically engaged in the integration of phonological and lexical information essential for phonological and derivational-morphological gender assignment.

Topics: Adult; Aged; Analysis of Variance; Aphasia; Case-Control Studies; Decision Making; Frontal Lobe; Functional Laterality; Humans; Male; Mental Processes; Middle Aged; Reaction Time; Recognition, Psychology; Reference Values; Semantics; Sex; Temporal Lobe; Verbal Behavior; Vocabulary

Topics: Aging; Aphasia; Carotid Artery Thrombosis; Cerebral Angiography; Diagnosis, Differential; Headache; Humans; Infarction, Middle Cerebral Artery; Intracranial Embolism; Intracranial Embolism and Thrombosis; Seizures; Sex; Thrombosis