sodium-dodecyl-sulfate and Vaginitis

sodium-dodecyl-sulfate has been researched along with Vaginitis* in 4 studies

Trials

2 trial(s) available for sodium-dodecyl-sulfate and Vaginitis

Article	Year
A double-blind comparison of active and inert douches in vaginitis. Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:11 Topics: Adult; Age Factors; Borates; Candida albicans; Clinical Trials as Topic; Female; Humans; Methods; Placebos; Sampling Studies; Sodium Dodecyl Sulfate; Solutions; Trichomonas vaginalis; Vaginitis	1973
[Clinical experiences with a new vaginal drug]. Medizinische Monatsschrift, 1972, Volume: 26, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Benzoates; Chlorine; Clinical Trials as Topic; Drug Combinations; Female; Hexestrol; Humans; Lactose; Leukorrhea; Middle Aged; Sodium Dodecyl Sulfate; Sulfonamides; Vagina; Vaginitis	1972

Other Studies

2 other study(ies) available for sodium-dodecyl-sulfate and Vaginitis

Article	Year
Entry of inflammatory cells into the mouse vagina following application of candidate microbicides: comparison of detergent-based and sulfated polymer-based agents. Sexually transmitted diseases, 2002, Volume: 29, Issue:10 Because topical microbicides designed to prevent the spread of sexually transmitted diseases may be applied frequently, it is important to ensure product safety as well as efficacy. A murine model was developed to test for induction of inflammatory responses following application of candidate microbicides.. A comparison was made of the induction of inflammation following vaginal application of detergent-based and sulfated polymer-based microbicides.. Vaginal leukocytes were collected, identified, and quantified following microbicide application to detect the entry of inflammatory leukocytes into the vaginal lumen.. Large numbers of neutrophils and macrophages entered the vaginal lumen following a single application of detergent-based microbicides. No significant increase in vaginal leukocytes was detected following a single or repeated application of sulfated polymer-based microbicides.. Application of sulfated polymer-based microbicides was less likely to result in inflammatory responses than was application of detergent-based compounds. This murine model should prove useful as part of a screening process to prioritize candidate microbicides before clinical trial. Topics: Administration, Intravaginal; Animals; Anti-Infective Agents, Local; Cell Count; Drug Evaluation, Preclinical; Female; Flow Cytometry; Macrophages; Mice; Models, Animal; Neutrophils; Nonoxynol; Sodium Dodecyl Sulfate; Vagina; Vaginal Creams, Foams, and Jellies; Vaginitis	2002
[Etiologic therapy of fluor vaginalis]. ZFA. Zeitschrift fur Allgemeinmedizin, 1981, Feb-20, Volume: 57, Issue:5 Topics: Adolescent; Adult; Aged; Drug Combinations; Drug Therapy, Combination; Estradiol; Female; Humans; Lactose; Leukorrhea; Middle Aged; Sodium Dodecyl Sulfate; Sulfonamides; Vaginitis	1981

Article

Year

Entry of inflammatory cells into the mouse vagina following application of candidate microbicides: comparison of detergent-based and sulfated polymer-based agents.

Sexually transmitted diseases, 2002, Volume: 29, Issue:10

Because topical microbicides designed to prevent the spread of sexually transmitted diseases may be applied frequently, it is important to ensure product safety as well as efficacy. A murine model was developed to test for induction of inflammatory responses following application of candidate microbicides.. A comparison was made of the induction of inflammation following vaginal application of detergent-based and sulfated polymer-based microbicides.. Vaginal leukocytes were collected, identified, and quantified following microbicide application to detect the entry of inflammatory leukocytes into the vaginal lumen.. Large numbers of neutrophils and macrophages entered the vaginal lumen following a single application of detergent-based microbicides. No significant increase in vaginal leukocytes was detected following a single or repeated application of sulfated polymer-based microbicides.. Application of sulfated polymer-based microbicides was less likely to result in inflammatory responses than was application of detergent-based compounds. This murine model should prove useful as part of a screening process to prioritize candidate microbicides before clinical trial.

Topics: Administration, Intravaginal; Animals; Anti-Infective Agents, Local; Cell Count; Drug Evaluation, Preclinical; Female; Flow Cytometry; Macrophages; Mice; Models, Animal; Neutrophils; Nonoxynol; Sodium Dodecyl Sulfate; Vagina; Vaginal Creams, Foams, and Jellies; Vaginitis

2002

[Etiologic therapy of fluor vaginalis].

ZFA. Zeitschrift fur Allgemeinmedizin, 1981, Feb-20, Volume: 57, Issue:5

Topics: Adolescent; Adult; Aged; Drug Combinations; Drug Therapy, Combination; Estradiol; Female; Humans; Lactose; Leukorrhea; Middle Aged; Sodium Dodecyl Sulfate; Sulfonamides; Vaginitis

1981