sodium-dodecyl-sulfate has been researched along with Osteosarcoma* in 2 studies
2 other study(ies) available for sodium-dodecyl-sulfate and Osteosarcoma
| Article | Year |
|---|---|
Composition and posttranslational modification of individual collagen chains from osteosarcomas and osteofibrous dysplasias.
The composition of collagen was analyzed and the degree of lysyl hydroxylation of individual collagen chains was determined in four osteosarcomas and two osteofibrous dysplasias. In addition, the tumor proliferation (number of mitoses, proliferating-nuclear-antigen-positive cells, MIB) as well as the response to chemotherapy (morphological regression grade) were checked. All tumors contained a high proportion of collagen III and, in all but one osteosarcoma, pepsin-extracted collagens I and III were overmodified. Furthermore, the proportion of diglycosides in collagen I was about four times higher than in controls. The collagen composition and modification resembled those of bones at early stages of human development. One osteosarcoma and both osteofibrous dysplasias were in the normal range of lysyl hydroxylation. There was no correlation between the collagen properties and the histopathological marker of tumor proliferation. Topics: Adolescent; Adult; Bone Neoplasms; Cell Division; Child; Collagen; Electrophoresis, Polyacrylamide Gel; Fibrous Dysplasia of Bone; Glycosylation; Humans; Hydroxylation; Hydroxylysine; Lysine; Osteosarcoma; Proline; Protein Processing, Post-Translational; Sodium Dodecyl Sulfate | 1995 |
Antiviral and cell multiplication inhibitory activities of mouse interferon poreparations tested on an interferon sensitive murine sarcoma cell line.
The cell multiplication inhibitory effect of SDS-treated mouse interferon separated into antiviral (AV) and cell multiplication inhibitory (CMI) fractions was compared to that of untreated similar interferon on a line of murine osteosarcoma cells. The untreated interferon poreparatin and the CMI fractions dose-dependently inhibited the multiplication of the cells as measured by cell count and incorporation of 3H-thymidine into the cultures. The AV fractions, containing comparable antiviral activites as the untreated interferon preparations, had only a minor effect on cell multiplication. The biochemical properties of the fractions studied remain unknown. Topics: Animals; Bone Neoplasms; Cell Count; Cell Division; Cell Line; Chromatography, Gel; Interferons; Mice; Mice, Inbred C57BL; Osteosarcoma; Sarcoma, Experimental; Sodium Dodecyl Sulfate; Virus Replication | 1980 |